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Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers reported. The study results are significant because until now, the most important marker for kidney disease has been protein (or albumin) in the urine. Up to half of diabetes patients who develop kidney failure never have much protein in their urine. As 90% of patients with diabetes (more than 37 million patients in the U.S.) remain at increased risk despite low levels of albumin...

Story at-a-glance: * A carnivore or meat-only diet can be uniquely beneficial for some people, especially those struggling with autoimmune diseases, Crohn’s disease, ulcerative colitis, chronic pain and mental health disorders * It can also be used as a detox strategy for three to 12 months * One of the primary benefits of a carnivore diet — as long as you focus on red meat and limit chicken and pork — is that it’s a really low in omega-6 fat, which is the most harmful type of fat and a primary driver of chronic disease * You’re also removing most...

Scientists have discovered that certain metals found in people's urine, could be potentially useful clinical biomarkers for the early detection of acute kidney injury (AKI). Acute Kidney Injury (AKI) is a rapid deterioration in kidney function over hours or days. It is common, occurring in 10–20% of patients admitted to hospital and about 50% of patients admitted to intensive care. It is widely accepted by clinicians that one of the main ongoing problems in managing AKI is the inability to detect it at a very early stage. Currently AKI is defined by a rise in a blood test, serum creatinine,...