Dialogues Health. 2022 Dec; 1: 100074.Published online 2022 Nov 10. doi: 10.1016/j.dialog.2022.100074PMCID: PMC9647013PMID: 36785641 Associated DataData Availability StatementData for Pfzier/BioNTech BNT162b2: https://doi.org/10.1056/nejmoa2034577; data for Moderna mRNA-1273: https://doi.org/10.1056/NEJMoa2035389 (accessed on 10 January 2021).Go to:AbstractTreatment and vaccine efficacy in clinical trials are often reported in the media and medical journals as the relative risk reduction. The present article explains why the relative risk reduction is a misinformative measure that promotes disinformation when reporting efficacy in clinical research studies such as randomized controlled trials for COVID-19 vaccines. The relative risk reduction is based on the relative risk, a proportional measure or ratio used...