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Study: Nighttime Eating Affects Body Clock, Can Lead to Glucose Intolerance
UPI ^ | DEC. 3, 2021 | Brian P. Dunleavy

Posted on 12/09/2021 4:08:30 PM PST by nickcarraway

Eating at night may increase a person's risk for glucose intolerance, or prediabetes, a study published Friday by the journal Science Advances found.

Confining meals to daytime can help maintain healthy blood glucose levels, allowing the body to more effectively process sugars, the researchers said.

After assessing the effects of nighttime eating on night shift workers, it appears that food consumption during the overnight hours causes a misalignment between the body's central and peripheral circadian "clocks," they said.

Circadian clocks are the body's natural timekeepers that regulate physical, mental and behavioral changes throughout the day.

In addition to applying to night shift workers, the findings could have implications for others who eat meals at atypical times, such as those experiencing jet lag or sleep disorders, or people who tend to sleep late on weekends, the researchers said.

"Of the participants studied, those with the biggest disruption of their circadian system ... showed the largest impairment of glucose tolerance," study co-author Frank A.J.L. Scheer said in a statement provided by Brigham & Women's Hospital in Boston, at which he works.

These participants had evidence of "misalignment between their central circadian clock and their endogenous circadian glucose rhythms," said Scheer, director of the Medical Chronobiology Program in the hospital's sleep and circadian disorders division.

Glucose intolerance results in high levels of the sugar in the bloodstream, a precursor for Type 2 diabetes, a condition that affects 30 million people in the United States, according to the Centers for Disease Control and Prevention.

In people with Type 2 diabetes, the body is less able to absorb sugar from the bloodstream into its tissues, causing dangerously high levels that can lead to serious health complications.

Night shift workers, who typically sleep during daytime and eat in the evening, have as much as a 60% higher risk for developing Type 2 diabetes compared with day-shift workers, research suggests. That is perhaps because of the body's reduced ability to process sugars overnight.

Such metabolic processes are governed by the body's circadian rhythms, which rise and fall during the 24-hour day, according to the CDC.

The brain's circadian clock sets the timing for many circadian rhythms, which regulate processes such as sleep and wake cycles, hormonal activity and eating and digesting.

For this study, Scheer and his colleagues assessed the effects of nighttime eating in 19 healthy young participants who stayed awake for 32 hours in a highly controlled, dimly lit environment, where they kept constant body posture and consumed identical snacks every hour.

Following this period, the participants engaged in a simulated night work schedule and followed one of two eating schedules, the researchers said.

One group ate during the nighttime to simulate a schedule typical among night shift workers, while the other ate during daytime, thus aligning the meal schedule to that of the central circadian clock.

Then, participants followed a second, 40-hour constant routine schedule to assess the effects of the meal schedules on their circadian rhythms.

Participants who ate during nighttime had increased blood glucose levels, while those who ate only during daytime experienced no significant changes, the data showed.

In addition, nighttime eating reduced pancreatic beta-cell function, which impacted affected participants' ability to process sugars, the researchers said.

Beta cells produce insulin, a hormone that helps the body process sugar.

Nighttime eating also caused a misalignment in participants' central circadian clocks, as estimated from changes in body temperature and blood glucose levels, according to the researchers.

Meanwhile, circadian rhythms that govern body temperature and glucose levels remained aligned when participants ate meals during the daytime, even with mistimed sleep.

"These results indicate that meal timing was primarily responsible for the reported effects on glucose tolerance and beta cell function," Scheer said.

"While the central circadian clock still was on Boston time, the endogenous circadian glucose rhythms suggest that some peripheral clocks, perhaps those in the liver, had shifted dramatically to a time zone in Asia," he said.


TOPICS: Food; Health/Medicine; Science
KEYWORDS: diabetes; glucose; metabolic
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1 posted on 12/09/2021 4:08:30 PM PST by nickcarraway
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To: nickcarraway
19 healthy young participants who stayed awake for 32 hours in a highly controlled, dimly lit environment, where they kept constant body posture and consumed identical snacks every hour.

I don't know about you, but I think it might be a challenge to maintain constant body posture for 32 hours. Unless they strapped me to a gurney.

2 posted on 12/09/2021 4:11:39 PM PST by ProtectOurFreedom (“…in any great disaster, there's a Harvard man in the middle of it.” ~ Thomas Sowell)
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To: ProtectOurFreedom

I’m not sure what such a bizarre test is supposed to prove. I guess if you stay awake in one position for 32 hours regularly you shouldn’t eat at night.


3 posted on 12/09/2021 4:16:37 PM PST by Seruzawa ("The Political left is the Garden of Eden of incompetence" - Marx the Smarter (Groucho))
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To: nickcarraway

No nightime eating/snacking for me! Food just fills me up so I can’t drink as much. Bourbon over broccoli any night of the week.


4 posted on 12/09/2021 4:17:09 PM PST by BipolarBob (WHY are there no Democrats on Mt. Rushmore?)
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To: nickcarraway

Our cat didn’t turn her clock back and she’s driving us nuts , Food Late


5 posted on 12/09/2021 4:17:50 PM PST by butlerweave
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To: BipolarBob
Bourbon over broccoli any night of the week.

That is disgusting!

Bourbon should be over ice not broccoli.

If you must you can have pickled cauliflower as a snack but not IN the bourbon.

What kind of monster are you?

6 posted on 12/09/2021 4:20:41 PM PST by Harmless Teddy Bear (add a dab of lavender in milk, leave town with an orange and pretend you're laughing with it)
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To: Harmless Teddy Bear
many apologies my good sir. Darn my poor typing skills. No I would never pour bourbon over broccoli. I meant I chose drinkin' bourbon over the choice of eating broccoli.
7 posted on 12/09/2021 4:24:29 PM PST by BipolarBob (WHY are there no Democrats on Mt. Rushmore?)
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To: Harmless Teddy Bear

LOL!


8 posted on 12/09/2021 4:24:37 PM PST by Obadiah (Fauci is the golden calf of science.)
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To: nickcarraway

pick 8 hours a day to eat your meals. Intermittent fasting is the answer.


9 posted on 12/09/2021 4:24:54 PM PST by devane617 (RUN FOR LOCAL ELECTED OFFICE! COUNCIL,SCHOOL BOARD, ETC.)
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To: nickcarraway

Circadian rhythm theme day I see.


10 posted on 12/09/2021 4:26:02 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: ifinnegan

Hopefully.


11 posted on 12/09/2021 4:26:40 PM PST by nickcarraway
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To: BipolarBob
Well any sane person would make that choice.

I am glad it was just a typo. The idea of pouring bourbon over broccoli!

:shutter:

So uncivilized. I could not believe a FReeper of your stature would do such a thing.

12 posted on 12/09/2021 4:27:49 PM PST by Harmless Teddy Bear (add a dab of lavender in milk, leave town with an orange and pretend you're laughing with it)
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To: nickcarraway

I never eat after 6p, or drink any liquids after 8p.


13 posted on 12/09/2021 4:28:07 PM PST by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: devane617

I only eat once a day. Have for years. Ever since an unknown stomach virus wrecked my guts.

Usually after 9 pm

But, I’m not exactly a model of health either


14 posted on 12/09/2021 4:34:44 PM PST by digger48
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To: nickcarraway

I’ll eat when I’m hungry, I’ll drink when I’m dry
If the hard times don’t kill me, I’ll lay down and die
I’ll tune up my fiddle and I ‘ll rosin my bow
I’ll make myself welcome, wherever I go.

Rye whiskey, rye whiskey, rye whiskey I cry
If I don’t get rye whiskey, I think I will die.

https://www.youtube.com/watch?v=EhhlHVsaUOA


15 posted on 12/09/2021 4:35:25 PM PST by Repeal The 17th (Get out of the matrix and get a real life.)
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To: nickcarraway

It’s also not good to eat after a certain hour at night to prevent acid reflux. My gastroenterologist told me years ago, not to eat a meal after 8 p.m., because your body produces most of the acid in your stomach while you sleep.


16 posted on 12/09/2021 4:35:54 PM PST by mass55th ("Courage is being scared to death, but saddling up anyway." ~~ John Wayne )
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To: devane617

I can go 3-4 days without eating and not think a thing about it

Used to weigh as much as 260. Now I can barely keep it over 150


17 posted on 12/09/2021 4:36:42 PM PST by digger48
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To: Seruzawa

It’s hard to get to the refrigerator if you don’t move for 32 hours. Or to the bathroom.


18 posted on 12/09/2021 4:36:50 PM PST by ProtectOurFreedom (“…in any great disaster, there's a Harvard man in the middle of it.” ~ Thomas Sowell)
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To: Harmless Teddy Bear

Sheesh. Everyone knows you’re supposed to pour aquavit over broccoli, not bourbon.


19 posted on 12/09/2021 4:41:14 PM PST by Seruzawa ("The Political left is the Garden of Eden of incompetence" - Marx the Smarter (Groucho))
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To: carriage_hill

If you eat after dark the gabooboo man will get you.


20 posted on 12/09/2021 4:44:38 PM PST by chalkfarmer
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