Posted on 12/01/2016 2:19:03 PM PST by Red Badger
Results by Rose et al. overturn a theory that in order for short-term memories to exist, neurons that represent that memory must be constantly active. Instead, the neural activity supporting that memory need only arise when the person trying to recall it consciously focuses his or her attention on the memory. Credit: N.S. Rose et al.
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It's clear that your working memory—which holds attention on small things of short-term importance—works, or you wouldn't be able to remember a new phone number long enough to dial it.
Describing how it works, however—how the brain determines what to keep in mind, and what to set aside but keep handy for quick access—is a work in progress. Work that may sharpen our theory of the mind and even help people suffering from schizophrenia or depression.
"A lot of mental illness is associated with the inability to choose what to think about," says Brad Postle, a psychology professor at the University of Wisconsin-Madison. "What we're taking are first steps toward looking at the mechanisms that give us control over what we think about."
Postle's lab is challenging the idea that working memory remembers things through sustained brain activity. They caught brains tucking less-important information away somewhere beyond the reach of the tools that typically monitor brain activity—and then they snapped that information back into active attention with magnets.
Their latest study will be published Dec. 2 in the journal Science.
According to Postle, it's important to note that most people feel they are able to concentrate on a lot more than their working memory can actually hold. It's a bit like vision, in which it feels like we're seeing everything in our field of view, but details slip away unless you re-focus on them regularly.
"The notion that you're aware of everything all the time is a sort of illusion your consciousness creates," says Postle. "That is true for thinking, too. You have the impression that you're thinking of a lot of things at once, holding them all in your mind. But lots of research shows us you're probably only actually attending to—are conscious of in any given moment—just a very small number of things."
Postle's group conducted a series of experiments in which people were asked to remember two items representing different types of information (they used words, faces and directions of motion) because they'd be tested on their memories.
When the researchers gave their subjects a cue as to the type of question coming—a face, for example, instead of a word—the electrical activity and blood flow in the brain associated with the word memory disappeared. But if a second cue came letting the subject know they would now be asked about that word, the brain activity would jump back up to a level indicating it was the focus of attention.
"People have always thought neurons would have to keep firing to hold something in memory. Most models of the brain assume that," says Postle. "But we're watching people remember things almost perfectly without showing any of the activity that would come with a neuron firing. The fact that you're able to bring it back at all in this example proves it's not gone. It's just that we can't see evidence for its active retention in the brain."
The researchers were also able to bring the seemingly abandoned items back to mind without cueing their subjects. Using a technique called transcranial magnetic stimulation (TMS) to apply a focused electromagnetic field to a precise part of the brain involved in storing the word, they could trigger the sort of brain activity representative of focused attention.
Furthermore, if they cued their research subjects to focus on a face (causing brain activity associated with the word to drop off), a well-timed pulse of transcranial magnetic stimulation would snap the stowed memory back into attention, and prompt the subjects to incorrectly think that they had been cued to focus on the word.
"We think that memory is there, but not active," says Postle, whose work is supported by the National Institute of Mental Health. "More than just showing us it's there, the TMS can actually make that memory temporarily active again."
The study—conducted by Postle with Nathan Rose, a former UW-Madison postdoctoral researcher who is now a professor of psychology at the University of Notre Dame, and UW-Madison graduate students in psychology and neuroscience—suggests a state of memory apart from the spotlight attention of active working memory and the deep storage of more significant things in long-term memory.
"What's still unknown here is how the brain determines what falls away, and what enables you to retrieve things in the short-term if you need them," Postle says.
Studying how the brain apportions attention could eventually influence the way we understand and treat mental health disorders such as schizophrenia, in which patients focus on hallucinations instead of reality, and depression, which seems strongly related to spending an unhealthy amount of time dwelling on negative things.
"We are making some interesting progress with very basic research," says Postle. "But you can picture a point at which this work could help people control their attention, choose what they think about, and manage or overcome some very serious problems associated with a lack of control."
Explore further: Missed connections: As people age, memory-related brain activity loses cohesion
More information: "Reactivation of latent working memories with transcranial magnetic stimulation," Science, science.sciencemag.org/cgi/doi/10.1126/science.aah7011
Journal reference: Science search and more info website
Provided by: University of Wisconsin-Madison
Imagine this tool in the wrong hands, or even the right hands................
TMS is voodoo. It does not penetrate deep enough to do any real good. First they tried to market it as an alternative to ECT (elctro shock) for depression.
If true we should all emerge from the MRI having flashbacks to the womb.
I did.
Everything was black...................
For Hillary, they’d have to run it direct off a nuke power plant to generate enough juice to restore all the stuff she says she cannot recall.
LOL!
It can’t restore character, which she never had.
Even if Hillary remembered, she would claim not to.
You need a machines capable of reading memories without the person’s consent. And it needs to be able to distinguish between reality and fantasy. It must distinquish between real Arkancide and fantasy droning of wikileaks dude. Or it will get discredited.
memory tricks of professionals- wanna remember a number? Associate each number with a step you do every day (IE: Goign to your car in morning) so if you need to memorize soemthign like 47925 associate the 4 by picturing your car keys ontop of the number 4- the 7 associate with the front door (picture a big 7 on door as you reach for door knob) the 9 associate with driveway (picture big 9 with circle around it written in blue on driveway) associate the 2 with the car door- and the 5 picture it embroidered into your car seat-
It takes about 10-15 minutes to get it down- them ore ridiculous the steps/objects, the better- professionals can make these associations on the fly and remember them- but they practice every day-
None of this helps with alzheimers- but if you are havign trouble remember soemone’s phone number, SS number, house number- names or whatever- this will help
For a name- think of say Robert or Sally- Picture their face o na pumpkin, with their name carved out underneath the face or just picture the pumpkin with just the name on it- Everything you see that person, you’ll recall the pumpkin, and the name will be visible to you- You may have to keep reminding yourself for a few times a day for a few days- but it will become part of your memory if you do-
A frontal lobotomy would, in her case..............
I’m sure they are working on that angle as well...............
Many years ago an elderly female co-worker explained memory as failing in later years because we only have so many brain cells for storage and when we run out - we forget stuff.
She was absolutely correct.
I can remember being bitten by my puppy at age 2. I cannot remember what I just typed.
*&P(*^%^%*&^%&^5
I lose my glasses every day.............
There’s a remedy for that. Don’t take them off - and why do you take them off?????
wouldn’t be able to remember a new phone number long enough to dial it
When is the last time you dialed a number. I don’t remember any phone numbers. I know. Off topic.
A lot of us experienced that during the Obama regime. Thank God for Trump, our thought processes are returning to normal...
Try handwriting recollections in a notepad. You'd be surprised at what you can remember from when you were young. Sometimes it takes several goes at it over months, but details will emerge. Some stuff is lost forever, and some stuff is simply buried waiting to be revealed.
Warning. The “memories” aren’t necessarily accurate.
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