https://www.medchemexpress.com/SP2509.html
https://pmc.ncbi.nlm.nih.gov/articles/PMC11450372/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8610793/
https://en.wikipedia.org/wiki/PIR_(gene)
check later
Posted on 10/29/2024 1:18:14 PM PDT by Red Badger
Researchers have discovered the mechanism linking the overconsumption of red meat with colorectal cancer, as well as identifying a means of interfering with the mechanism as a new treatment strategy for this kind of cancer.
Meat is a significant source of protein and fat, as well as essential vitamins and minerals like iron, zinc, and vitamins A and B. However, as is the case with many things, eating too much of it is bad for you. Despite the strong evidence associating red meat with some cancers, the underlying mechanism is less clear.
Now, researchers from the National Cancer Center Singapore (NCCS), together with scientists from Singapore’s Agency for Science, Technology and Research (A*STAR), have identified the mechanism linking the excessive consumption of red meat to colorectal cancer.
Worldwide, colorectal cancer, which affects the large intestine or rectum, is the third most common cancer, accounting for around 10% of cancer cases. It’s also the second leading cause of cancer-related deaths. In addition to age and family history, lifestyle factors such as diet, inactivity, obesity, smoking, and excess alcohol consumption can increase the risk of this type of cancer.
Using fresh colorectal cancer samples, the researchers discovered that the iron in red meat reactivated the enzyme telomerase via an iron-sensing protein called Pirin, which drove the progression of the cancer. Now, this requires stepping back to explain the importance of telomerase and telomeres and their relation to cancer growth.
Telomeres, the little ‘caps’ found at the end of chromosomes, are made from DNA sequences and proteins and are required for cell division. With each cell division, the telomeres get shorter and shorter until they’re so short that cells can no longer divide. When cells can no longer divide, tissues age. However, the enzyme telomerase can rebuild telomeres to restore cell division.
(Excerpt) Read more at newatlas.com ...
“Knowing our stupid electorate they’ll run in fear from eating red meat-—the rest of us will enjoy an overabundance of red meat at a lower price.”
I used to agree with that, but the problem is that the political support for allowing us to eat meat will drop along with the meat eaters.
That is why I argued with the doctor and he agreed to reduce my statins from 20mg every day to 5 mg pills only on 3 days. Have not noticed any adverse side effects.
I am a believer in MINIMUM prescription pills.
I eat lots of frozen foods and restaurant food and order pizza delivery often, my blood pressure like to stay at 140/90 without Lisinopril. I use 10 mg Lisinopril minimum dose pills daily, and that keeps my BP at 130/80.
Again, real key to remain healthy is my daily moderate exercise. Today, I pressure washed my 2 car garage driveway. It took me 4 hours because it was full of black mold. Not too bad for a 84 year old dude.
Haha, most zoo animals are over-weight, compared to those in the wild.
Not having to fight for your food, or mate or shelter or anything else frankly does that.
But the ones in the Chinese Zoos are not just a bit on the pudgy side they are on the "oh those poor things" side.
It is really sad.
Yeah, tall people have a twenty percent higher chance at getting cancer just because taller means you have more cells and having more cells means there is a greater chance something will go wonky.
Which might be why fat people tend to get cancer at a greater rate as well.
But cancer has been found in the bones of our very remote ancestors so it was always around.
Good idea using a lower dosage and staying active. I’m about 15 years behind you, but still doing 50-mile bike rides.
Don’t blame the beef for what the bun did!
Overconsumption of red meat has to be a lot better for you than the vaxx.
They tell you what is actually good for you, by trying to stop you from consuming it.
Opposite also holds true (jabs, etc).
If true, then I should be dead by now.
No telomerase activators are approved currently for anti-aging purposes specifically because they might encourage malignancy and because so little research has been conducted on the topic.
Extracts from the astragalus plant are thought to have the potential to activate telomerase but the same question exists about the potential to stimulate cancer.
Must have been very rough being a plains Indian...
Who can even afford to overconsume red meat these days?
If you cook 2 lobsters with your steak it nullifies cancer cells. But it must be smothered in butter and lemon juice to get the healing properties just right.
Seems largely non specific nonsense.
The article never states what excessive consumption looks like and it states the iron from red meat. Is that different than iron from a hundred other sources? I thought iron was iron.
Fascinating. I will indeed contact you.
I miss making a nice burger with chopped onion and celery I mix in, nice salt-free catsup from Fred Meyer/Kroger on top. No bun, I don’t eat wheat.
My parents both died younger than I am. My sister too.
I eat all the right organic fruits and veggies, weigh 112, and try to walk at least half a mile every day. Exercise, I understand, is the most important thing to increase longevity.
My maternal greatgrandparents came from Ireland, so of course I eat potatoes.My beloved grandmother, who lived in New Orleans, called then “badaydahs” I buy organic potatoes. Every grocery store in my ‘hood has them: Safeway, Trader Joe, Natural Grocer, Fred Meyer/Kroger.
No big deal to find them elsewhere. I scrub them, cut them in half and steam them. Steaming is the easiest way to cook them and it preserves the most nutritional value. I steam veggies too.
You can fine little steamer inserts for pots at many grocery stores and, of course, at AMZ. Really cheap and they last forever.
https://www.medchemexpress.com/SP2509.html
https://pmc.ncbi.nlm.nih.gov/articles/PMC11450372/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8610793/
https://en.wikipedia.org/wiki/PIR_(gene)
check later
Or having iron-deficiency anemia.
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