A large segment of white middle-aged Americans has suffered a startling rise in its death rate since 1999, reversing decades of progress, according to a new review of statistics published Monday. The mortality rate for white men and women between the ages of 45 and 54 with less than a college education increased by half a percent per year between 1999 and 2013, most likely because of problems with legal and illegal drugs, alcohol, and suicide, according to the study released in the Proceedings of the National Academy of Sciences.... The rising death rate was accompanied by a parallel increase...