I went 12-2 straight up last week, and 10-4 against the spread. What follows are my picks for the NFL's Week 10: *Thursday, November 8* Indianapolis (5-3) at Jacksonville (1-7) - 8:20 p.m. (Line: Colts by 3) The Colts have won three in a row. The Jaguars have dropped five straight. They are winless at home this season and have the most inept offense in the league in terms of points per game, passing yards per game, and total yards per game. - RJ's Pick: Indianapolis by 7