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Research led by the German Institute of Human Nutrition (DIfE) has identified a new gene associated with diabetes, together with a mechanism that makes obese mice less susceptible to diabetes. A genomic fragment that occurs naturally in some mouse strains diminishes the activity of the risk gene Zfp69. The researchers also found that the corresponding human gene (ZNF642) is especially active in overweight individuals with diabetes. The results of the study, which also involved scientists from the University of Leipzig and the German Cancer Research Center in Heidelberg, are published July 3 in the open-access journal PLoS Genetics. According to...

Scientists in Canada and Scotland have developed a virus-free method for generating embryonic-like stem cells that does not involve destroying embryos. Scientists say the new approach to growing so-called induced pluripotent stem (iPS) cells is an important step toward creating safe and reliable populations of cells for research and therapy. To create iPS cells, researchers turn back the clock in mature cells. They do this by reactivating dormant genes associated with pluripotency--a primitive state in which a cell has the potential to become any cell type in the body. Scientists first introduced iPS cells in 2006 and since then have...