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Scientists package HDL with gene-silencing siRNA to target tumors, spare normal tissueHOUSTON - High-density lipoprotein's hauls excess cholesterol to the liver for disposal, but new research suggests "good cholesterol" can also act as a special delivery vehicle of destruction for cancer. Synthetic HDL nanoparticles loaded with small interfering RNA to silence cancer-promoting genes selectively shrunk or destroyed ovarian cancer tumors in mice, a research team led by scientists from The University of Texas MD Anderson Cancer Center and the University of North Texas Health Science Center reports in the April edition of Neoplasia. "RNA interference has great therapeutic potential but...

Marines Push North Along 'Ambush Alley' By ELLEN KNICKMEYER .c The Associated Press SOUTH-CENTRAL IRAQ (AP) - Thousands of Marines pushed north toward Baghdad in ``seek and destroy'' missions Sunday, trying to open the route to the Iraqi capital and stop days of attacks along a stretch that has become known as ``Ambush Alley.'' Charging into previously unsecured areas, the Marines tried to provoke attacks in order to find Iraqi fighters and defeat them. A chaplain traveling with them handed out humanitarian packages to distrustful Iraqi civilians encountered along the way. Army supply trucks appeared on the Marine route north...