Free Republic

A team of researchers working at the Indiana University School of Medicine, has developed a compound that can degrade the cancer-promoting protein SUMO1. In their paper published in the journal Science Translational Medicine, the group describes their work in attempting to find a degrader for what has been described as an undruggable cancer-related protein. Prior research has shown that there are some proteins that change cancer proteins in ways that help it form and spread, but which are considered to be undruggable, meaning that it appears unlikely that a drug could be developed that would prevent it from doing its...

One of the great scientific achievements of recent decades was the mapping and sequencing of human DNA completed by the Human Genome Project (HGP). During roughly the same period that that vast effort began to bear fruit (a working draft of the human genome sequence was announced in June 2000), resurgent and very militant voices of atheism also began to be heard more loudly than they had been for many years -- claiming, among other things, that belief in God is a relic of the primitive past that should be discarded in our scientific age. Somewhat awkwardly, though, it turns...