Keyword: regeneration
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I remember being a kid and seeing my grandmother without her dentures for the first time. It was a harrowing experience. Now my dad has dentures so, genetically speaking, I’m several decades out from needing some myself. However, it’s possible that modern medicine will solve the issue of lost teeth by then, thanks to a new drug that's about to enter human trials. The medicine quite literally regrows teeth and was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital....
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The world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030. The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar. The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side...
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The world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030. The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar. The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side...
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Researchers in Japan are currently working on a medication that would allow people to grow a new set of teeth, with a clinical trial slated for July 2024.
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Researchers report a discovery in cardiac regeneration that offers new hope for the treatment of ischemic heart failure. The study reveals a novel approach to promoting cardiomyocyte proliferation. "When the heart cannot replace injured cardiomyocytes with healthy ones, it becomes progressively weaker, a condition leading to heart failure. In this study, we investigated a new way to stimulate cardiomyocyte proliferation to help the heart heal," said Dr. Riham Abouleisa. Previous studies showed that calcium plays an important role in cardiomyocyte proliferation. In the current study, Abouleisa and her colleagues explored how modulating calcium influx in cardiomyocytes would affect their proliferation....
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CBN.com -Stephen Christo never wavered in his devotion to the array of Hindu gods and goddesses. And he wanted nothing to do with other religions, especially Christianity. “Because they were the only ones keep talking about their god. I said to people, hey, you got one. I got millions. I don't need your one." When Stephen turned 19 he left his home on the island of Trinidad, bound for the US. Naturally, his parents were worried but they also had good reason. Earlier in his teenage years, he developed a recurring illness that had been triggered by the common cold....
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Fittest Man in the World Owes His Success to a Fall CBN.com -Rich Froning has earned the title of “Fittest Man in the World” for four consecutive years. And, he’s the only competitor to ever accomplish that feat in the CrossFit Championships. But, Rich will tell you that his road to first, started with a fall. Rich was raised in a large Catholic family and had 24 male cousins. In his family, competition was the name of the game. “There's a lot of boys in that group there, so there’s a lot of testosterone at family get-togethers and it was...
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CBN.com – When John Collier was a child, his house was not a home. It was more like a battle zone. "My father had a background of violence," John tells The 700 Club. "He abused alcohol and drugs. He was a womanizer, and he pretty much terrorized our home." John’s anger toward his father grew. He stayed in trouble at school and ran away from home twice. "There was always that little boy in me that loved my dad. Then there was that other side of me that started to hate him and never want to be anything like he...
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Researchers from the University of Cologne have found a new use for cnicin, a substance produced in blessed thistle. Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae and also grows in our climate. For centuries, it has been used as a medicinal herb as an extract or tea, e.g. to aid the digestive system. Researchers at the Center for Pharmacology of University Hospital Cologne and at the Faculty of Medicine of the University of Cologne have now found a completely novel use for cnicin under the direction of Dr. Philipp Gobrecht and Professor Dr. Dietmar Fischer. Animal...
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Researchers have identified a novel macrolide–DEL-1 axis that helps in bone regeneration and new bone formation. This finding may lead to the development of therapeutic agents to treat bone loss disorders. Periodontitis is a serious gum infection that damages the soft tissue and destroys the bone that supports teeth. It is usually the result of poor oral hygiene that leads to bacterial infections. Aging may increase susceptibility to periodontitis by altering immune and regenerative functions. Development endothelial locus-1 (DEL-1), crucial for inflammation resolution and tissue repair, declines with age. The low levels of DEL-1 protein also affect bone regeneration and...
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Frogs, unlike their salamander cousins, cannot regenerate lost limbs, but a fascinating new experiment suggests it’s possible for frogs to partially regrow their missing body parts under the right conditions. A paper published today in Science Advances describes a new treatment that made it possible for African clawed frogs (Xenopus laevis) to partially grow back their amputated hind limbs. The treatment consisted of five different drugs and a wearable device, called “BioDome.” Exposure to this chemical cocktail for just 24 hours facilitated a regenerative period that last for 18 months, according to the research, led by researchers from Tufts University...
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Damage to the retina is the leading cause of blindness in humans, affecting millions of people around the world. Unfortunately, the retina is one of the few tissues we humans can't grow back. Unlike us, other animals such as zebrafish are able to regenerate this tissue that's so crucial to our power of sight. We share 70 percent of our genes with these tiny little zebrafish, and scientists have just discovered some of the shared genes include the ones that grant zebrafish the ability to grow back their retinas. "Regeneration seems to be the default status, and the loss of...
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When it comes to regeneration, some animals are capable of amazing feats. If you cut off a salamander’s leg, it will grow back. When threatened, some geckos drop their tails to distract their predator, only to regrow them later. Other animals take the process even further. Planarian worms, jellyfish, and sea anemones can actually regenerate their bodies after being cut in half. Led by Assistant Professor of Organismic and Evolutionary Biology Mansi Srivastava, a team of researchers is shedding new light on how animals pull off the feat, along the way uncovering a number of DNA switches that appear to...
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Groundbreaking surgery to regrow part of a human bone was carried out on Tuesday at HaEmek Hospital in the northern Israeli town of Afula. Danny, a resident of a nearby kibbutz who had part of his shinbone removed eight months ago after a car accident, was treated in the procedure, which was hailed by medical staff as “science fiction.” During the surgery, the first of its kind in the world, doctors took fat cells from the patient, grew them in a lab and injected them back into his body for them to generate the missing parts of the bone, the...
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For this morning, I want you to open the Word of God to the third chapter of John, back to the third chapter of John and the opening ten verses. Now, you who have been with us the last couple of weeks know how important and critical this portion of Scripture is. You know something about it now that we’ve sort of penetrated it at least as far as verse 3. The good news, we’ll finish all the way down to verse 10 this morning. I can’t exactly tell you when but we will finish verse 10. Now I’m going...
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p { margin-top: 0px; margin-bottom: 1px } <p>body { font-family: "Times New Roman", serif; font-size: 12pt; font-weight: normal; font-style: normal } Does Water Baptism Save? A Biblical Refutation of Baptismal Regeneration   Baptismal Regeneration is the teaching which says that water baptism is an essential requirement for salvation. According to this teaching, if a person desires to be born again (born into God's family) then he must be baptized in water. Those holding to this doctrine teach that apart from water baptism, a person cannot be saved, cannot be born again, cannot see the kingdom, and cannot enter heaven.   Introduction:...
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I grew up in a loving family who attended the Catholic Church regularly. Not just my immediate family, mind you(!) - but my entire family (aunts, uncles, cousins, grandparents, etc.) was Catholic! I was a regular participant and played the organ at church and also was a leader in the "folk choir" for most of my teenage years. In short - I was as "Catholic" as they come! I never doubted my faith because I was told to just believe everything the Church taught me without question. The Pope was supreme in his authority, and the priests and nuns were...
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Not long ago, it would have sounded like science fiction to discuss growing human organs in the lab or re-writing DNA. Yet today both are realities that will change the world and allow for longer and healthier lives. Already, lab-grown bladders, windpipes and blood vessels have been successfully created and implanted into humans. Most recently, tissue engineering pioneer Dr. Anthony Atala and his team at the Wake Forest Institute for Regenerative Medicine announced another breakthrough: lab-made vaginas—one of the most complex organs made to date. In four girls with MRKH syndrome, a medical condition in which the vagina and uterus...
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Fasting for as little as three days can regenerate the entire immune system, even in the elderly, scientists have found in a breakthrough described as “remarkable”. Although fasting diets have been criticized by nutritionists for being unhealthy, new research suggests starving the body kick-starts stem cells into producing new white blood cells, which fight off infection. Scientists at the University of Southern California say the discovery could be particularly beneficial for people suffering from damaged immune systems, such as cancer patients on chemotherapy. […] Scientists found that prolonged fasting also reduced the enzyme PKA, which is linked to aging and...
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LONDON (Reuters) - British scientists have for the first time used regenerative medicine to fully restore an organ in a living animal, a discovery they say may pave the way for similar techniques to be used in humans in future. The University of Edinburgh team rebuilt the thymus - an organ central to the immune system and found in front of the heart - of very old mice by reactivating a natural mechanism that gets shut down with age. The regenerated thymus was not only similar in structure and genetic detail to one in a young mouse, the scientists said,...
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