A new study by Texas A&M University scientists offers fresh clues to a long-standing puzzle: why people who drink coffee tend to live longer and develop fewer chronic diseases. Their results suggest brewed coffee contains compounds that interact with a little-understood protein in the body, potentially influencing inflammation, aging and cancer-related processes. Hailemariam et al. demonstrate that brewed coffee and its major polyphenolics and polyhydroxy constituents are NR4A1 ligands and that NR4A1 may play an important role in the health-protective effects of coffee. Image credit: Sci.News. “Coffee is the most highly consumed beverage worldwide,” said Texas A&M University’s Professor Stephen...