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  • Popular Sweetener Generates a Substance in the Body That Damages Human DNA

    10/28/2025 12:29:20 PM PDT · by nickcarraway · 22 replies
    Earth.com ^ | Jordan Joseph
    A lab team in North Carolina reports that a compound formed when people consume sucralose can damage DNA. The same compound also appears in trace amounts in some store bought sucralose. The team used human cells and lab grown gut tissue to probe effects of sucralose byproducts. A new study mapped DNA damage, gut barrier changes, and gene activity. “Our new work establishes that sucralose-6-acetate is genotoxic,” says Susan Schiffman, corresponding author of the study and an adjunct professor in the joint department of biomedical engineering at North Carolina State University (NCSU) and the University of North Carolina at Chapel...