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New research suggests that patients who have insufficient levels of vitamin D before starting paclitaxel treatment are more likely to experience peripheral neuropathy. According to an analysis of 1,191 patients with early-stage breast cancer—using data collected in the SWOG S0221 study—20.7% of patients with vitamin D deficiency experienced at least a grade 3 level of chemotherapy-induced peripheral neuropathy (CIPN), compared to 14.2% of those with sufficient vitamin D levels. The researchers also found that inducing vitamin D deficiency in an accompanying mice model study caused neurotoxicity-like symptoms. "These results suggest that vitamin D supplementation in patients with lower levels of...

THOSE of us who knew from the beginning that the sequence of CoV-SARS-2 contained inserts which could not have possibly occurred naturally, and were similar to ones that had already been published from the Wuhan laboratory, have had to endure unbelievable scorn, scientific ostracism and the ignominy of being ‘cancelled’ by the MSM as well as by professional colleagues for nearly three years now. In the summer of 2020 a paper I co-authored, describing the findings of an Anglo-Norwegian team of scientists who had demonstrated unique ‘fingerprints’ of laboratory manipulation in the Covid virus, was suppressed in both the US...

Oncologist: “I’ve Never Seen Cancers Behaving Like This” So strange they’ve given it a brand new name: “Turbo Cancer”. How terrible is that? The name is exactly what it sounds like — cancers so extreme and so aggressive that you’re often dead within months. Unlike anything doctors have seen before in their careers. Now gee, I wonder what could have caused that? Did we embark on any massive exploratory new drug or inoculation recently with no prior safety testing? Anything like that come to mind? Crimes Against Humanity. Just watch this if you can stomach it: VIDEO AT LINK............... It’s...

Investigators have found that dasatinib, a drug commonly used to treat chronic myeloid leukemia, is strongly associated with kidney injury. The study team strongly believes this study will impact clinical practice significantly, changing standard of care and possibly introducing new black box warnings for dasatinib. Furthermore, the researchers point out that the incidence of kidney injury is a previously unknown severe side effect for this drug. This side effect, they report, is advertised to be rare; however, they observed it in 10% of all participants taking dasatinib. Of concern, they say, is that patients taking dasatinib are currently not screened...

Back in the 1920s, researchers discovered that cancer patients had sweet-smelling urine. First, the doctors were puzzled, but they soon realized that it was a result of elevated blood sugar levels. "In cancer patients, the cells do not respond well to the hormone insulin. It therefore takes more insulin to create the same effect in cancer patients. If you suffer from insulin resistance, your body has to produce more insulin than usual to be able to regulate the blood sugar," says Lykke Sylow. The body's ability to respond to insulin is impaired in both cancer patients and people with type...

The FDA-approved lung cancer drug osimertinib (sold under the brand name Tagrisso) slashes the risk of death by 51% for certain patients whose cancer is caught early, according to new trial data. “This should be the new standard of care for these patients,” Nathan Pennell, co-director of the Cleveland Clinic Lung Cancer Program, who wasn’t involved in the drug’s development, said in a statement for the American Society of Clinical Oncology. The drug: Lung cancer is the second-most common cancer in the world, with 2.2 million new diagnoses every year. The vast majority fall into a category called “non-small cell...

A little-noticed provision of the omnibus spending bill could give the agency power to ban off-label use of approved therapies.. Secreted within the 2023 omnibus appropriations bill—4,155 pages, spending $1.7 trillion—is a 19-line section that could change the way medicine is practiced. Physicians routinely prescribe drugs and employ medical devices that are approved and labeled by the Food and Drug Administration for a particular use. Yet sometimes physicians discern other beneficial uses for these technologies, which they prescribe for their patients without specific official sanction. The new legislation amends the Food, Drug and Cosmetic Act, or FDCA, to give the...

Continued treatment for patients with cancer near end-of-life escalates costs and may adversely affect the quality of care patients receive. Accordingly, over the last decade, major professional societies have recommended that clinicians decrease the use of systemic anti-cancer therapies at the end-of-life stage. Researchers revealed that despite these recommendations, aggressive cancer care at the end-of-life persists and there has been a substantial transition from the use of chemotherapy to immunotherapy. "Systemic anti-cancer therapy has changed dramatically following the approvals of multiple new targeted therapies," said Kerin Adelson, MD. Researchers used the nationwide Flatiron Health electronic health record (EHR)-derived database to...

Study finds certain immune cells sometimes ‘switch sides’ and actually help tumors grow; finding has implications for improving immunotherapyWhen working correctly, your immune system detects and responds to pathogens ranging from viruses to parasitic worms, as well as cancer cells and foreign objects such as wood splinters. Researchers at Tel Aviv University recently discovered that the cells in certain cancer patients can act as “double agents,” helping cancerous tumors grow rather than eradicate them. The study, published in the Cell Reports, found that immune cells called neutrophils play a critical role in interacting with cancerous growth. Neutrophils are continuously recruited...

A team of researchers working at the Indiana University School of Medicine, has developed a compound that can degrade the cancer-promoting protein SUMO1. In their paper published in the journal Science Translational Medicine, the group describes their work in attempting to find a degrader for what has been described as an undruggable cancer-related protein. Prior research has shown that there are some proteins that change cancer proteins in ways that help it form and spread, but which are considered to be undruggable, meaning that it appears unlikely that a drug could be developed that would prevent it from doing its...

Ingredients found in hair dye and anti-ageing cream could delay breast cancer progression by two years, scientists believe. Early research suggests they boost the effectiveness of radiotherapy when injected into a tumour before treatment. The cocktail of hydrogen peroxide, which bleaches hair, and hyaluronic acid, which moisturises skin, costs less than £100....

Using CT scans, researchers discovered a malignant bone cancer in the fibula of a horned dinosaur that lived 75 million years ago. Photo by Royal Ontario Museum/McMaster University =========================================================================== Aug. 4 (UPI) -- For the first time, scientists have diagnosed a dinosaur with osteosarcoma, an aggressive, malignant bone cancer, according to a study published in The Lancet Oncology. The tumor was found on the fibula, or lower leg bone, of a Centrosaurus apertus specimen, a plant-eating, horned dinosaur that lived 75 million years ago. Shortly after its original discovery in Dinosaur Provincial Park in Alberta in 1989, paleontologists misdiagnosed the...

A newly discovered network of fluid-filled channels in the human body may be a previously-unknown organ, and it seems to help transport cancer cells around the body. This discovery was made by chance, from routine endoscopies – a procedure that involves inserting a thin camera into a person’s gastrointestinal tract. Newer approaches enable doctors to use this procedure to get a microscopic look at the tissue inside a person’s gut at the same time, with some surprising results. {snip} This organ was likely never seen before because standard approaches for processing and visualising human tissue causes the channels to drain,...

Doctors using a treatment called nivolumab on a lung cancer patient with Aids noticed a “drastic and persistent” decrease in infected white blood cells A new cancer drug could “cure” HIV, a revolutionary study suggests. Doctors using a treatment called nivolumab on a lung cancer patient with Aids noticed a “drastic and persistent” decrease in infected white blood cells. The findings have raised hopes that drugs could one day eradicate the HIV virus, which attacks the immune system and cur­­rently has no cure. At present, those infected must take anti-HIV drugs for the rest of their lives to stop the...

Researchers at Case Western Reserve University School of Medicine have discovered a mutant form of the gene, Chk1, that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without the addition of any chemotherapeutic drugs. This study illustrates an unprecedented finding, that artificially activating Chk1 alone is sufficient to kill cancer cells. "We have identified a new direction for cancer therapy and the new direction is leading us to a reduction in toxicity in cancer therapy, compared with chemotherapy or radiation therapy," said Dr. Zhang, assistant professor, Department of Pharmacology at the School of Medicine, and...

NEW YORK (Reuters) - In a move that threatens to further inflame concerns about the rationing of medical care, the nation's leading association of cancer physicians issued a list on Wednesday of five common tests and treatments that doctors should stop offering to cancer patients. The list emerged from a two-year effort, similar to a project other medical specialties are undertaking, to identify procedures that do not help patients live longer or better or that may even be harmful, yet are routinely prescribed

Doctors have treated only three leukemia patients, but the sensational results from a single shot could be one of the most significant advances in cancer research in decades. And it almost never happened. In the research published Wednesday, doctors at the University of Pennsylvania say the treatment made the most common type of leukemia completely disappear in two of the patients and reduced it by 70 percent in the third. In each of the patients as much as five pounds of cancerous tissue completely melted away in a few weeks, and a year later it is still gone

Hello Everybody, Over the past 7 ½ years I have written a couple of times to tell you stories about my son’s battle with cancer. I now have one last story to tell. And I want you to hear it. This last story begins with a boat. The boat is not much to look at anymore because it has aged a lot since the day it was built. I am sure a boat of this size had a name but I can’t find it anywhere, and it has been painted so many times that the original color is no longer...

There's a new da Vinci in town -- but this one is devoted to the surgeon's art. Newark Beth Israel Medical Center is opening its Robotic Training Center, featuring the new $1.5 million da Vinci S Surgical System. The new system allows for greater precision in performing minimally invasive operations. Doctors from all over the world are expected to train at the center -- one of only three sites in the country to have the latest da Vinci robot. The other two are The Methodist Hospital in Houston, affiliated with the Weill Medical College of Cornell University, and the Sunnyvale,...

On Feb. 3, Joyce Elkins filled a prescription for a two-week supply of nitrogen mustard . . . The cost was $77.50. On Feb. 17, Ms. Elkins, a 64-year-old retiree . . . returned to her pharmacy for a refill. This time . . . the cost was $548.01. Ms. Elkins's insurance does not cover nitrogen mustard, which she must take for at least the next six months at a cost that will now total nearly $7,000. She and her husband . . . are paying for the medicine by spending less on utilities and food, she said. The medicine...