January 17, 2008 — Inadvertent and inappropriate administration of edetate disodium (Endrate, Hospira, Inc, and generics) can lead to serious adverse events, the US Food and Drug Administration (FDA) warned healthcare professionals yesterday. Inadvertent use of edetate disodium rather than edetate calcium disodium (also known as calcium disodium versenate) has led to deaths in adults and children, according to an alert sent from MedWatch, the FDA's safety information and adverse event reporting program. According to the FDA, the major risks are thought to apply only to the short period of time after edetate disodium use; onset of death and serious...