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New bioarchaeological research shows malaria has threatened human communities for more than 7000 years, earlier than when the onset of farming was thought to have sparked its devastating arrival..."Until now we've believed malaria became a global threat to humans when we turned to farming, but our research shows in at least Southeast Asia this disease was a threat to human groups well before that."This research providing a new cornerstone of malaria's evolution with humans is a great achievement by the entire team," Dr Vlok says...While malaria is invisible in the archaeological record, the disease has changed the evolutionary history of...

Resistance to the gold-standard malaria treatment, the drug artemisinin, has been rising in southeast Asia for a decade — and there is evidence that artemisinin-based therapies might start to fail in Rwanda, too. In Asia, artemisinin drug resistance has been linked to various mutations in the ‘K13’ section of the genome of the most deadly malaria parasite, Plasmodium falciparum. Aline Uwimana at the Rwanda Biomedical Centre in Kigali, Didier Menard at the Pasteur Institute in Paris and their colleagues detected K13 mutations in P. falciparum parasites collected from people with malaria in Rwanda. The team genetically modified parasites to harbour...

As the world battles the novel Coronavirus pandemic, there is a surge in demand for hydroxychloroquine (HCQ), a common anti-malarial drug that, in some quarters, has been touted as a possible “miracle drug” in the fight against COVID-19. The world has knocked the doors of India to get supplies of this drug, given that it produces nearly half the world's HCQ tablets. It'll be interesting to note that the history of this "game-changer" drug goes two centuries back all the way to the British imperial expansion in India. According to a Twitter thread by a user named Primordial Kāshyap, hydroxychloroquine's...

Top Medical Body ICMR Issues Revised Advisory On Use Of Anti-Malarial Drug Hydroxychloroquine The revised advisory issued by the ICMR on Friday, however, cautioned that the intake of the medicine should not instill a sense of false security. Press Trust of India NDTV May 23, 2020 New Delhi:  A revised government advisory has recommended use of hydroxychloroquine as a preventive medication for asymptomatic healthcare workers working in non-COVID-19 hospitals, frontline staff on surveillance duty in containment zones and paramilitary/police personnel involved in coronavirus infection related activities. As was mentioned in the earlier advisory, the drug against the infection is also...

Anyone remember these? They've been off market for years. My Mom cured everything from a cold to chicken pox with this stuff. We all took it. It is QUININE.. similar to the malaria drug they are testing for the Pelosi (China) Virus. Quinine is the generic form of the brand-name drug qualaquin, a medication used to treat uncomplicated P. falciparum malaria, a specific type of malaria. SEE also: Here's a vintage commercial for 4-Way Cold Tablets, showing the difference between it and a regular cold capsule in terms of the relief that is offered - 4-Way providing relief for nasal...

A new survey from Jackson & Coker shows an overwhelming majority of doctors would prescribe hydroxychloroquine or another anti-malaria drug to a family member suffering from Wuhan coronavirus. "Sixty-five percent of physicians across the United States said they would prescribe the anti-malaria drugs chloroquine or hydroxychloroquine to treat or prevent COVID-19 in a family member," the survey, which questioned 1,271 doctors in 50 states, found. "Only 11 percent said they would not use the drug at all." In addition, a significant number of doctors said they would prescribe the drugs to those exposed to the virus as a preventative measure...

After reading the paper, https://archive.is/ONUmi, about the way COVID-19 makes people ill, it strikes me that there may be a quicker, and cheaper, way to screen for infected people. It may not be 100%, but it may be a start.

Well, that didn't take long.CNN host John Berman had hoped to talk about the – reading now from the lower third on the screen –"HEATED DISAGREEMENT IN WH SITUATION ROOM OVER UNPROVEN DRUG"! QUICK, AN ARGUMENT! SOMEONE DO SOMETHING! TRUMP WILL KILL US ALL! ORANGE MAN BAD!Instead what he got from Trade Representative Peter Navarro, who's on the Trump administration's coronavirus task force, was an education.As Real Clear Politics helpfully transcribed, Berman was trying to talk up the reported argument Navarro had with Dr. Anthony Fauci over trying the FDA approved malaria drug, hydroxychloroquine on coronavirus patients. Fauci says...

The HuffPost on Tuesday published a story claiming President Trump owned a share in a company that manufactured hydroxychloroquine, the anti-malaria drug the president and others have touted as a possible treatment for coronavirus. The story, titled “Donald Trump Has Stake In Hydroxychloroquine Drugmaker: Report,” argues that Trump “reportedly owns a stake in a company that produces hydroxychloroquine, the anti-malaria drug he has repeatedly touted as a coronavirus treatment even though his experts say there’s no strong evidence it works.” The story goes on to cite a New York Times story that Trump “has a small personal financial interest” in...

In the last 3–5 days, a mountain of anecdotal evidence has come out of NYC, Italy, Spain, etc. about COVID-19 and characteristics of patients who get seriously ill. It’s not only piling up but now leading to a general field-level consensus backed up by a few previously little-known studies that we’ve had it all wrong the whole time. Well, a few had some things eerily correct (cough Trump cough), especially with Hydroxychloroquine with Azithromicin, but we’ll get to that in a minute. There is no ‘pneumonia’ nor ARDS. At least not the ARDS with established treatment protocols and procedures we’re...

this insanity from Rep. Tavia Galonski about The Hague and charging Trump with ‘crimes against humanity’ takes the insanity cake. I can’t take it anymore. I’ve been to The Hague. I’m making a referral for crimes against humanity tomorrow. Today’s press conference was the last straw. I know the need for a prosecution referral when I see one. https://t.co/XQin24gqY4 — Rep. Tavia Galonski

Democratic state representative in Ohio said she "can't take it anymore" and vowed to refer President Trump to the International Criminal Court for "crimes against humanity" over Trump's promotion of a drug that has not been conclusively proven to fight the coronavirus. State Rep. Tavia Galonski tweeted Sunday after President Trump spoke about hydroxychloroquine at his daily press briefing. The drug, normally used to treat malaria, is one of several that the president has pointed to as showing promise in the fight against COVID-19, but its effectiveness has been a subject of debate. "I can’t take it anymore. I’ve been...

World Health Organization The Wuhan virus has shown that even during pandemics, the WHO will put politics ahead of public health. During a recent interview with Hong Kong news outlet RTHK, Bruce Aylward, a physician and senior adviser to the World Health OrganizationÂ’s director general, refused to answer a question about TaiwanÂ’s handling of the COVID-19 pandemic. A clip of the exchange has been viewed thousands of times on Twitter, and there are growing calls for Aylward to explain himself.DonÂ’t expect him to. AylwardÂ’s behavior is just the latest in a long line of instances of the WHO putting politics...

Doctors in Italy have finally began widely prescribing hydroxychloroquine in certain combinations in Rome and the wider region of Lazio with a population of around six million. According to Corriere della Sera, a well known Italian daily newspaper, Dr. Pier Luigi Bartoletti, Deputy National Secretary of the Italian Federation of General Practitioners, explains that every single person with Covid-19 that has early signs, like a cough or a fever for example, is now being treated with the anti-malaria drug. The drug “is already giving good results,” Bartoletti says while Malaysia reveals they have been using it since the very beginning....

From a disease standpoint, Shakespeare was living in arguably the worst place and time in history. Shakespeare's overcrowded, rat-infested, sexually promiscuous London, with raw sewage flowing in the Thames, was the hub for the nastiest diseases known to mankind. Here are the worst of the worst. 1. Plague It is little surprise that the plague was the most dreaded disease of Shakespeare's time. Carried by fleas living on the fur of rats, the plague swept through London in 1563, 1578-9, 1582, 1592-3, and 1603 (Singman, 52). The outbreaks in 1563 and 1603 were the most ferocious, each wiping out over...

Shares of others in the race may lose momentum Companies working on COVID-19 treatment and prevention have seen their shares soar so far this year. Moderna (NASDAQ: MRNA) gained 44%, Regeneron Pharmaceuticals (NASDAQ: REGN) rose 15%, Gilead Sciences (NASDAQ: GILD) climbed 9%, and Inovio Pharmaceuticals (NASDAQ: INO) soared 102%.These stocks may lose momentum if chloroquine becomes the "go-to" drug for COVID-19. As mentioned above, there is room for additional treatments, but if chloroquine gets the first-mover advantage, others that eventually enter probably will seize a smaller share of the market than hoped. The news also would burst the bubble of...

Bahrain and Belgium report their hospitals are successfully treating coronavirus patients with the anti-malaria drug hydroxychloroquine touted by President Trump as a possible breakthrough in the pandemic. The Kingdom of Bahrain's Supreme Council of Health chairman said his country was among the first to use the drug and that its impact has been "profound," according to the Bahrain News Agency. Dr. Shaikh Mohamed, who leads the National Taskforce for Combating COVID-19, was also quoted by the news agency as saying hydroxychloroquine was administered according to the same regimens as those used in China and South Korea. The first COVID-19 case...

Bahrain and Belgium report their hospitals are successfully treating coronavirus patients with the anti-malaria drug hydroxychloroquine touted by President Trump as a possible breakthrough in the pandemic. The Kingdom of Bahrain's Supreme Council of Health chairman said his country was among the first to use the drug and that its impact has been "profound," according to the Bahrain News Agency.

Some doctors are writing prescriptions for a drug that may help treat coronavirus for their family and friends, one pharmacist said, calling their actions "unethical and selfish." Hydroxychloroquine has not been clinically proven to be safe or successful in treating coronavirus, and yet the increased demand for it is making it harder for people who need it to control their chronic diseases to get it. Hydroxychloroquine is a less toxic derivative of chloroquine, an anti-malaria drug. It often treats autoimmune diseases, such as lupus and rheumatoid arthritis, and is sold under the brand name, Plaquenil. Recent data show chloroquine orders...

**SNIP** “I was at the point where I was barely able to speak, and breathing was very challenging,” Giardinieri said. “I really thought my end was there.” On Friday, he said goodbye to his wife and three children, thinking he would be the next victim of the COVID-19 virus. Then a friend sent him an article about hydroxychloroquine. **SNIP** Thirty minutes later, nurses administered the drug, and for two hours, he felt his heart race and experienced an episode where he couldn’t breathe. He then woke up at 4:45 the next morning and felt “like nothing ever happened." His breathing...