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A study has explored whether adding branched-chain amino acids (BCAAs) to an exercise program could improve outcomes for older adults. In a small, randomized, double-blind, placebo-controlled trial, the team found that BCAA supplementation improved performance, reduced fatigue, and alleviated depression symptoms for many participants. His research focuses on how inflammation impairs central nervous system function. BCAAs—leucine, isoleucine, and valine—are essential amino acids that not only serve as the building blocks of protein and muscle but also appear to play specific roles in inflammation and brain health. "Through supplementation, we thought perhaps we could restore balance and reduce the burden of...

Research in mice shows limited intakes of one particular essential amino acid can slow the impacts of aging and even lengthen their lifespan. Scientists are now wondering if these findings could help people improve their longevity and quality of life. Isoleucine is one of three branched-chain amino acids we use to build proteins in our bodies. It is essential for our survival, but since our cells can't produce it from scratch, we have to get it from sources like eggs, dairy, soy protein and meats. But there can always be too much of a good thing. Earlier research using data...

Scientists have identified a less stringent and more manageable alternative to traditional intermittent fasting, offering new possibilities for extending lifespan and promoting healthy aging. This novel method, involving short-term isoleucine deprivation, has shown remarkable results in fruit flies (Drosophila melanogaster). The research found that intermittent, short-term omission of only the essential amino acid isoleucine from the diet significantly increases stress resistance and extends lifespan in fruit flies. "Unlike conventional intermittent fasting, this approach does not require drastic reductions in overall food intake, making it a more practical and feasible strategy," said Tahila Fulton. Previous research has shown that moderate restriction...