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Keyword: insulin

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  • New research challenges notion that post-meal insulin surge is a bad thing

    12/18/2023 10:15:35 AM PST · by ConservativeMind · 31 replies
    Researchers have unearthed vital information about the relationship between insulin levels after eating and long-term heart and metabolic health. The research upends the notion that insulin surge following food intake is a bad thing. Normally, insulin levels rise after eating to help manage blood sugar. However, the concern is whether a rapid increase in insulin after a meal could spell bad health. The study followed new mothers. The interpretation of insulin levels from the test can be misleading if one does not account for baseline blood sugar. "It's not just about insulin levels; it's about understanding them in relation to...
  • Study directly links high insulin levels to pancreatic cancer

    11/02/2023 8:11:37 PM PDT · by ConservativeMind · 7 replies
    A study reveals a direct link between high insulin levels, common among patients with obesity and type 2 diabetes, and pancreatic cancer. The study provides the first detailed explanation of why people with obesity and type 2 diabetes are at an increased risk of pancreatic cancer. The research demonstrates that excessive insulin levels overstimulate pancreatic acinar cells, which produce digestive juices. This overstimulation leads to inflammation that converts these cells into precancerous cells. "Alongside the rapid increase in both obesity and type 2 diabetes, we're seeing an alarming rise in pancreatic cancer rates," said Dr. James Johnson. "These findings help...
  • 10 drugs targeted for Medicare price negotiations as Biden pitches cost reductions

    08/30/2023 11:36:14 AM PDT · by Red Badger · 47 replies
    AOL ^ | August 29, 2023 at 2:26 PM | CHRIS MEGERIAN, TOM MURPHY AND AMANDA SEITZ
    WASHINGTON (AP) — President Joe Biden, struggling to convince Americans that he's improved their lives as he runs for reelection, hailed his administration's Tuesday announcement that several drugs would be targeted for Medicare's first-ever price negotiations. The drugs include the blood thinner Eliquis, diabetes treatment Jardiance and eight other medications. The negotiation process was authorized under the Inflation Reduction Act, which Biden signed last year, capping decades of debate over whether the federal government should be allowed to haggle with pharmaceutical companies. Any lower prices won't take effect for three years, and the path forward could be further complicated by...
  • New research finds deep-sleep brain waves predict blood sugar control

    07/08/2023 7:56:35 PM PDT · by ConservativeMind · 6 replies
    Researchers have known that a lack of quality sleep can increase a person's risk of diabetes. What has remained a mystery, however, is why. Now, a team of sleep scientists have uncovered a potential mechanism in humans that explains how and why deep-sleep brain waves at night are able to regulate the body's sensitivity to insulin, which in turn improves blood sugar control the next day. "These synchronized brain waves act like a finger that flicks the first domino to start an associated chain reaction from the brain, down to the heart, and then out to alter the body's regulation...
  • Meta-analysis explores the mechanism that connects cancer and diabetes (Cancer associated with insulin resistance & high insulin encourages cancer growth)

    06/22/2023 7:48:36 PM PDT · by ConservativeMind · 7 replies
    Back in the 1920s, researchers discovered that cancer patients had sweet-smelling urine. First, the doctors were puzzled, but they soon realized that it was a result of elevated blood sugar levels. "In cancer patients, the cells do not respond well to the hormone insulin. It therefore takes more insulin to create the same effect in cancer patients. If you suffer from insulin resistance, your body has to produce more insulin than usual to be able to regulate the blood sugar," says Lykke Sylow. The body's ability to respond to insulin is impaired in both cancer patients and people with type...
  • Plant-based insulin derived from lettuce, can be taken orally

    06/15/2023 1:26:31 PM PDT · by Red Badger · 3 replies
    New Atlas ^ | June 15, 2023 | By Bronwyn Thompson
    Animal cells share some qualities with plant cells, but one key feature ours lack is a rigid cell wall. While this provides structure for plants, it’s also something scientists are increasingly looking at for use in new materials, cellulose technology and, now, insulin delivery. Led by Henry Daniell from the University of Pennsylvania’s School of Dental Medicine, researchers have created a promising plant-based insulin, containing the three peptides that occur naturally in insulin, which can also be ingested orally. Just as important as the genetic material on the inside, the plant cell walls are key to the drug's efficacy. Their...
  • New research reveals how vitamin K helps protect against diabetes (Pancreatic beta cells need it)

    05/20/2023 6:45:02 PM PDT · by ConservativeMind · 28 replies
    Canadian researchers have identified a new role for vitamin K and gamma-carboxylation in beta cells and their potentially protective role in diabetes. The study explains, at least in part, how vitamin K helps prevent diabetes, and could lead to new therapeutic applications for type 2 diabetes. Vitamin K is a micronutrient known for its role in blood clotting, in particular in gamma-carboxylation, an enzymatic reaction essential to the process. It has been suspected for several years that this vitamin, and thus gamma-carboxylation, may have other functions as well. Several studies suggest a link between a reduced intake of vitamin K...
  • Sugar-powered implant produces insulin as needed...It could revolutionize diabetes management.

    04/04/2023 6:03:16 AM PDT · by Red Badger · 8 replies
    FreeThink ^ | April 2, 2023 | By Kristin Houser
    Credit: Fussenegger Lab / ETH Zurich / Annelisa Leinbach Swiss researchers have developed a sugar-powered implant that automatically produces insulin when blood glucose levels are high — potentially giving people with diabetes an easier, less-painful way to manage their condition. Diabetes management: For people with type 1 diabetes (T1D), the body doesn’t produce enough (or any) insulin, a hormone that converts blood sugar into energy. To prevent their blood glucose levels from being dangerously high, they need regular injections of synthetic insulin. People who manage their diabetes manually must give themselves these painful injections multiple times a day. Those who...
  • Pomegranates Fuel Tumor-Fighting Cells

    02/15/2023 10:57:49 AM PST · by Red Badger · 10 replies
    Epoch Times ^ | February 15, 2023 | Joseph Mercola
    Urolithin A, a metabolite of ellagitannins in pomegranates, boosts immune cells’ ability to combat tumors by inducing a process known as mitophagy. STORY AT-A-GLANCE Urolithin A (UA) has emerged as a powerhouse player in the fight against cancer, as it may naturally boost tumor-fighting immune cells. UA is a metabolite of ellagitannins in pomegranates that has anti-inflammatory and anticancer effects. UA “recycles and renews mitochondria” by inducing a biological pathway known as mitophagy—the process of cleaning out your mitochondria, allowing them to function at their best. This changes T cells’ genetic program, making them more able to fight tumors. In...
  • Artificial Pancreas Developed That Can Help Maintain Healthy Glucose Levels in Type 2 Diabetes Patients

    01/11/2023 12:44:41 PM PST · by Red Badger · 10 replies
    Scitech Daily ^ | JANUARY 11, 2023 | By UNIVERSITY OF CAMBRIDGE
    Artificial Pancreas Successfully Trialed for Use by Type 2 Diabetes Patients Scientists at the University of Cambridge have successfully trialed an artificial pancreas for use by patients living with type 2 diabetes. The device – powered by an algorithm developed at the University of Cambridge – doubled the amount of time patients were in the target range for glucose compared to standard treatment and halved the time spent experiencing high glucose levels. Around 415 million people worldwide are estimated to be living with type 2 diabetes, which costs around $760 billion in annual global health expenditure. According to Diabetes UK,...
  • Exercise can help against insulin resistance in the brain (Just eight weeks)

    11/08/2022 8:38:35 AM PST · by ConservativeMind · 5 replies
    If the brain no longer responds correctly to the hormone insulin (insulin resistance), this also has a negative effect on the metabolism in the body and the regulation of eating behavior. A recent study shows that as little as eight weeks of exercise can help restore the brain's insulin sensitivity in severely overweight adults. This opens up new therapeutic possibilities for reducing obesity and diabetes risk factors in the future. Fourteen women and seven men aged 21–59 years with a body mass index of 27.5–45.5 took part in the study. Functional magnetic resonance imaging (MRI) was used to determine insulin...
  • Biden Claims He Spoke to the Man Who ‘Invented’ Insulin, Who Died Before He Was Born

    11/02/2022 1:44:43 PM PDT · by SmokingJoe · 26 replies
    PJMedia ^ | NOVEMBER 02 2022 | Robert Spencer
    Snopes and are unlikely to tell you this, but I will: insulin wasn’t actually invented at all. Insulin is a hormone produced within the body. In 1923, Frederick Banting and J.J.R. Macleod were awarded the Nobel Prize in Physiology or Medicine for discovering insulin. So right off the bat, what Old Joe Biden says is hogwash: no one “invented” insulin, unless Joe meant that he was talking to the God whom he otherwise ignores unless he feels it necessary to flaunt his alleged Catholic piety for political purposes. But giving Joe the benefit of the doubt, maybe he meant...
  • Biden says he 'spoke to' man who 'invented' insulin, who died before president was born

    11/01/2022 4:41:30 PM PDT · by DadOfFive · 49 replies
    President Joe Biden told a room full of supporters in Hallandale Beach, Florida, on Tuesday that he spoke with the man who "invented" insulin, who said it was never patented because it was supposed to be available to everyone. The president was giving a speech to gain support for the Democratic Party going into the midterms. A Novo Nordisk employee controls a machine at an insulin production line in a plant in Kalundborg A Novo Nordisk employee controls a machine at an insulin production line in a plant in Kalundborg (Reuters) During his speech, Biden spoke about the Inflation Reduction...
  • Herschel Walker Says People Worried About High Insulin Costs Should Just 'Eat Right'

    10/15/2022 6:46:35 AM PDT · by Lower Deck · 202 replies
    Huff Po ^ | 10/15/22 | Igor Bobic
    Herschel Walker, the GOP nominee for a U.S. Senate seat in Georgia, said people who are worried about the high cost of insulin should “eat right” in his only debate against Sen. Raphael Warnock (D-Ga.) on Friday. During an exchange about the economy and the high cost of living, Warnock touted his work passing legislation lowering prescription drug prices, including a $35 cap on monthly insulin costs. He noted that Walker had opposed the law, which is called the Inflation Reduction Act. Walker responded by saying the Inflation Reduction Act had not reduced inflation. Then he argued that people who...
  • Liver protein protects against stiff arteries in obesity and diabetes (Adropin increasable by diet and weight loss)

    09/21/2022 8:18:56 AM PDT · by ConservativeMind · 9 replies
    New research identifies the importance of the protein adropin in preventing stiffness in the arteries of people with obesity and type 2 diabetes. Arterial stiffness is a condition associated with aging and insulin resistance, a chronic condition associated with obesity, and is a major contributor in the development of cardiovascular disease, including heart attack and stroke. Adropin, a protein produced by the liver and other tissues, is involved in maintaining energy balance in the body and the metabolism of fat and sugar. Previous studies have suggested that adropin also plays a role in regulating cardiovascular health. People with chronic conditions...
  • Study reverses long-held ideas about relationship among diabetes, fat and cardiovascular disease (Vascular issue causes diabetes)

    08/06/2022 9:47:06 PM PDT · by ConservativeMind · 15 replies
    Medical Xpress / Joslin Diabetes Center / Circulation Research ^ | August 5, 2022 | Jacqueline Mitchell / Kyoungmin Park et al
    A major risk factor for diabetes, insulin resistance occurs when the cells of the body do not respond to insulin and cannot make use of the glucose (sugar) in the blood stream. The condition is known to increase the risk of cardiovascular disease and atherosclerosis. George King, MD, identified a pathway in which the cells lining the blood vessels—called endothelial cells—drive the body's metabolism. In a reversal of scientific dogma, the findings suggest that vascular dysfunction may itself be the cause of undesirable metabolic changes that can lead to diabetes, not an effect as previously thought. In addition to being...
  • Protein discovery points to entirely new way to treat type 2 diabetes

    08/05/2022 9:03:59 AM PDT · by Red Badger · 15 replies
    New Atlas ^ | August 04, 2022 | By Rich Haridy & Mount Sinai
    New research points to a novel way to prevent the death of insulin-producing beta cells A study led by researchers from the Icahn School of Medicine at Mount Sinai has homed in on a newly discovered molecular mechanism that could prevent insulin resistance in type 2 diabetics. The research indicates disrupting the expression of a certain protein could protect beta cells and prevent patients from becoming insulin resistant. Type 2 diabetes can develop when insulin-producing beta cells in the pancreas become dysfunctional, often following long-term high blood glucose levels. Eventually, those crucial beta cells begin to die, with the body...
  • Western diets rich in fructose and fat cause diabetes via glycerate-mediated loss of pancreatic islet cells

    Those who are habitually inclined to consume burgers, fries and soda may think twice about their dietary choices following scientists' latest findings about high-fat, high-fructose diets. A team discovered that a high-fat diet can increase fructose metabolism in the small intestine, leading to release of a fructose-specific metabolite called glycerate into circulation. Circulating glycerate can subsequently cause damage of the insulin-producing pancreatic beta cells, increasing the risk of glucose tolerance disorders, such as Type 2 diabetes mellitus (T2DM). Past research has shown that fructose produces deleterious effects in the liver. However, additional research has shown that these effects are normally...
  • Regular blueberry consumption may reduce risk of dementia, study finds (A half cup of blueberries a day for 12 weeks: Fasting insulin improved ~20%, some cognitive/verbal issues decreased ~80%)

    05/11/2022 7:03:05 PM PDT · by ConservativeMind · 21 replies
    Medical Xpress / University of Cincinnati / Nutrients ^ | May 11, 2022 | Robert Krikorian et al
    Researchers led by UC's Robert Krikorian, Ph.D., found that adding blueberries to the daily diets of certain middle-aged populations may lower the chances of developing late-life dementia. Krikorian explained that about 50% of individuals in the U.S. develop insulin resistance, commonly referred to as prediabetes, around middle age. Prediabetes has been shown to be a factor in chronic diseases, he said. "We had observed cognitive benefits with blueberries in prior studies with older adults and thought they might be effective in younger individuals with insulin resistance," said Krikorian. "Alzheimer's disease, like all chronic diseases of aging, develops over a period...
  • Medication Shows Benefits Treating Type 1 Diabetes – Delayed Disease Progression, Lowered Insulin Requirements

    03/03/2022 7:56:36 AM PST · by Red Badger · 5 replies ^ | March 3, 2022 | By UNIVERSITY OF ALABAMA AT BIRMINGHAM
    Benefits of the blood pressure medication verapamil include delayed disease progression, lowered insulin requirements, and preservation of some beta cell function. Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications. Patients taking the oral blood pressure medication not only required less daily insulin two years after first diagnosis of the disease, but also showed evidence of surprising immunomodulatory benefits. Continuing medication was necessary. In the two-year study, subjects who stopped daily doses of verapamil at one year saw their disease at two years...