An affordable and effective nutritional approach to help reduce inflammation and prevent type 2 diabetes

Medical Xpress / University of Montreal / Scientific Reports ^ | Dec. 2, 2024 | Valérie Lamantia et al

[ConservativeMind]

A team sheds new light on the role of marine-source omega-3 supplementation in treating adipose tissue inflammation and reducing the risk for cardiometabolic diseases like type 2 diabetes.

The study reveals that subjects with high numbers of blood low density lipoproteins (LDL)—commonly known as "bad cholesterol"—have higher inflammation in their adipose tissue than those with low LDL. The team also demonstrated that, in subjects with high blood LDL, adipose tissue inflammation was associated with abnormalities in carbohydrate (sugar) and fat metabolism that increase the risk for type 2 diabetes.

Furthermore, the study revealed that fish-oil omega-3 supplementation was effective in inhibiting the effects of LDL on adipose tissue inflammation and its association to risk factors for type 2 diabetes and cardiovascular disease. Omega-3 supplementation also improved the anomalies in carbohydrate and fat metabolism in all subjects.

To understand how LDL and omega-3 impact the risk of developing type 2 diabetes, Dr. Faraj's team recruited 40 healthy volunteers for a clinical study between 2013 and 2019. Of these, 33 volunteers completed a 12-week intervention with omega-3 supplementation providing 2.7 g of EPA and DHA in fish-oil per day. This dose of EPA and DHA is within the range recommended for supplementation by Health Canada.

The Faraj team found that EPA and DHA supplementation:

—Improved the body's secretion of insulin in response to increased blood glucose and its clearance of blood fat after a high-fat meal.

—Hindered subjects' LDL ability to trigger inflammation in their own adipose tissue.

—Eliminated the link between adipose tissue inflammation induced by LDL, or other metabolic and microbial inflammatory triggers, with several risk factors for type 2 diabetes and cardiovascular diseases.

—The higher were the levels of EPA and DHA in the blood, the better was the treatment of the cardiometabolic risk factors.

[ConservativeMind]

2.7 grams of combined EPA/DHA Omega-3 fats broke the ability for LDL to trigger fat inflammation, over 12 weeks. It also helped the insulin response.

Basic fish oil capsules have 300 mg of these combined fats, so you would need to eat the right fish or supplement with higher concentrations.

[ConservativeMind]

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[Jane Long]

Carlson 😉

[Valpal1]

Just eat sardines in olive oil every day.

[Veto!]

I use Carlson too.

[ProtectOurFreedom]

1. 2,700 mg combined EPA/DHA Omega-3 fats broke the ability for LDL to trigger fat inflammation

2. Basic fish oil capsules have 300 mg of these combined fats

I take Antarctic Krill Oil daily from Amazon / Vivanaturals. One serving (2 capsules) contains 165 mg EPA + 90 mg DHA = 255 mg combined. I'm WAY below that 2,700 target.

Note the "% Daily Value" numbers. If I upped my Krill Oil intake by 10.6X, I'd be ingesting 20% of my daily fat allowance and 50% of daily cholesterol allowance.

[Jane Long]

Carlson is the very best.

[JesusIsLord]

Some years back, studies came out claiming omega-3 fish oil supplements may increase, not reduce, the risk of first-time stroke and atrial fibrillation among people in good cardiovascular health.

Today, this is so much contrary information regarding supplements and other things, it's difficult to discern what's true.

[caver]

What is Carlson?

[Jane Long]

https://carlsonlabs.com/the-carlson-omega-3-difference/

[Jane Long]

One of my faves ... but, they have MANY great EPA/DHA/Omega 3 products...

https://carlsonlabs.com/cod-liver-oil/

[caver]

Thank you!

[sauropod]

.

[ckilmer]

I take about 2 grams of fish oil. I used to take 4 grams until I read reports that the higher doses might cause affib. So I lowered my dose to 500 mg. In the last month I raised the dose to the current 2 grams because, it does a better job of balancing my moods.

I have some inflammation issues in my shoulders that cause me pain.

Did you experiment with higher and lower doses of fish oil before you arrived at 2.7 grams

[AnglePark]

Ping

[jonrick46]

"33 volunteers completed a 12-week intervention with omega-3 supplementation providing 2.7 g of EPA and DHA in fish-oil per day.

Was this a combined 2.7 g of EPA and DHA or 2.7 g of EPA and 2.7 g of DHA? It spells poor writing on the crucial information on dose.

[43north]

So, 9 caps of fib oil per day? That will make for some unpleasant belches 😩

[SharpRightTurn]

I haven’t looked back to see if my memory is failing me on this point or not, but I think you may have shared a recent report that fish oil capsules may not be good for those who are concerned about prostrate cancer. Is that right?

[ConservativeMind]

It’s combined, so they add up to that.

[ConservativeMind]

It was recently found to be slightly associated with prostate cancer:

https://freerepublic.com/focus/f-chat/4278262/posts