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Keyword: fluconazole

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  • Keto diet boosts lifesaving antifungal drug in mice

    05/16/2024 7:45:25 PM PDT · by ConservativeMind · 3 replies
    Medical Xpress / Keck School of Medicine of USC / Duke University / mBio ^ | May 8, 2024 | RA Smith / Julia R. Palmucci et al
    For the roughly 150,000 AIDS patients who come down with a life-threatening infection called fungal meningitis each year, there's only one treatment: a drug called fluconazole that works for less than half of patients. Now, a study suggests there may be a way to improve the odds—simply by changing what patients eat. In animal tests, the researchers found that taking fluconazole in combination with a low-carb, high-fat keto diet worked significantly better at killing the fungus than taking the medication alone. For the new study, the researchers wondered if a keto diet—which deprives the body of glucose by cutting carbohydrate...