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In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid. The research team studies illnesses which are caused by misfolded proteins, of which Alzheimer's disease in the brain is the most well-known example. The researchers noted that there are many similarities between COVID-19-related symptoms and those which are observed in illnesses caused by misfolded proteins. Using computer simulation, the researchers discovered that the coronavirus'...

Alzheimer’s Breakthrough: Scientists Home In On Molecule Which Halts Development of Disease Cambridge scientists raise prospect of new generation of treatments after finding technique to limit development of biggest cause of dementia By John Bingham, 16 Feb 2015 Scientists have found a method which could potentially stop the growth of Alzheimer’s disease in its tracks, raising the prospect of a wave of new treatments for the condition. A team at Cambridge University, working with partners in Sweden and Estonia, has identified a molecule which can block the progress of Alzheimer’s at a crucial stage in its development. Not only is...