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Aerobic exercise reprograms the immune system to reduce pancreatic tumor growth and amplify the effects of immunotherapy, a study finds. The study provides new insight into how the mammalian immune system, designed to attack foreign invaders like bacteria, can also recognize cancer cells as abnormal. Exercise-induced increases in levels of the hormone adrenalin cause changes to the immune system, say the study authors, including in the activity of cells that respond to signaling protein interleukin-15 (IL-15). Biological systems that fight disease and repair tissue are intertwined, the researchers say, with IL-15 signaling, based on the context, either encouraging the recovery...

When should I fit exercise within my schedule? For most, the answer depends on our family's schedule and working hours. Recent findings suggest that the effectiveness of exercise depends on the time of day (Exercise Time Of Day, ETOD). Now, a randomized controlled trial not only confirms convincingly that ETOD affects the effectiveness of exercise, but also shows that these effects differ between types of exercise, and between women and men. Investigator Dr. Paul J Arciero, said: "Here we show for the first time that for women, exercise during the morning reduces belly fat and blood pressure, whereas evening exercise...

Exercise increases levels of a chemical involved in brain cell growth, which bolsters the release of the "feel good" hormone dopamine, a new study shows. Dopamine is known to play a key role in movement, motivation, and learning. Experts have long understood that regular running raises dopamine activity in the brain and may protect nerve cells from damage. In addition, past research has tied exercise-driven boosts in the dopamine-triggering chemical called brain-derived neurotrophic factor (BDNF) and in dopamine levels to improvements in learning and memory. Researchers showed that mice running on a wheel for 30 days had a 40% increase...

Structured aerobic exercise training over 12 weeks improves blood vessel function in people with stage 3 and 4 chronic kidney disease (CKD), according to a new study by physiologists at Emory University School of Medicine in Atlanta. Researchers also found that exercise reduced blood pressure reactivity in this population. The article is published ahead of print in the Journal of Applied Physiology. This study was conducted in 38 men—primarily Black men—and 10 women with CKD who were randomly split among a structured and a supervised group. The aerobic "spin" group rode stationary bikes and the non-aerobic group participated in stretching...

A diet involving short-term, severe calorie restriction was safe, feasible, and resulted in a decrease of blood glucose and growth factor concentration, reduction in peripheral blood immunosuppressive cells, and enhanced intratumor T-cell infiltration in cancer patients receiving standard-of-care therapy, according to a trial. Preclinical research has demonstrated that severe calorie restriction in the form of cyclic fasting or fasting-mimicking diet (FMD) has potent anticancer effects when combined with standard pharmacological treatments. The researchers administered an FMD regimen to the study participants that consisted of a five-day, low-carbohydrate, low-protein, plant-derived diet, which provided up to 600 Kcal on day 1 and...

Scientists at Newcastle University have shown that physical activity causes the cancer-fighting protein, interleukin-6 (IL-6), to be released into the bloodstream which helps repair the DNA of damaged cells. The findings, published in the International Journal of Cancer, sheds new light on the importance of moderate activity in the fight against the life-threatening illness and could help develop treatments in the future. Repairing DNA Dr. Sam Orange, Lecturer in Exercise Physiology at Newcastle University, said: "Previous scientific evidence suggests that more exercise is better for reducing bowel cancer risk as the more physical activity people do, the lower their chances...

Talmud-ist Maimonides (1138-1204) urges to make exercise: One should work or exert himself in some other way. The rule is that he should engage his body and exert himself in a sweat-producing task each morning. Afterwards, he should rest slightly until he regains composure and [then, he should] eat. If he were to bathe in hot water after exerting himself, it would be beneficial. Afterwards, he should wait a short while and eat.

There are a ton of misinformation-peddlers out there, lurking in the shadows, trying to kill you with misinformation. Here at the Babylon Bee, we care deeply about your safety, so we told our best researchers to compile a list of COVID treatments the CDC has NOT approved. Avoid these at all costs! 1) Drinking plenty of water: Please. Do you know what else drinks water? A horse. 2) Spending some time in the warm, pleasant Sun: This sun imbues us with Vitamin D, which the CDC has not approved for protection against COVID. Get inside now!!! 3) Getting a nice...

More than 100,000 Americans died from diabetes in 2021, marking the second consecutive year for that grim milestone and spurring a call for a federal mobilization similar to the fight against HIV/AIDS. The new figures come as an expert panel urges Congress to overhaul diabetes care and prevention, including recommendations to move beyond a reliance on medical interventions alone. The nation’s toll from diabetes has increased sharply, surpassing 100,000 deaths in each of the last two years and representing a new record. Diabetes-related deaths surged 17% in 2020 and 15% in 2021 compared to the prepandemic level in 2019. …"Type...

If everyone between 40 and 85 years of age were active just 10 minutes more a day, it could save more than 110,000 U.S. lives a year, a large study reports. "Our projections are based on an additional 10 minutes of moderate to vigorous physical activity," said lead researcher Pedro Saint-Maurice of the Metabolic Epidemiology Branch at the U.S. National Cancer Institute in Bethesda, Md. "If the walk is brisk, it counts." And added exercise benefits everyone—white, Black, Asian and Hispanic, men and women, the investigators found. For the study, the researchers examined data from more than 4,800 middle-aged and...

An oral supplement intended to stimulate a natural body process appears to promote muscle endurance and mitochondrial health in humans. New research suggests that the supplement, urolithin A, may help improve or prolong muscle activity in people who are aging or who have diseases that make exercise difficult. Urolithin A is a byproduct of a person's gut bacteria and a diet comprising polyphenols found in pomegranates, berries and nuts. The compound also is produced and sold by dietary supplement companies. Supplemental urolithin A has been shown in animal tests and molecular studies of humans to stimulate mitophagy, a process that...

"The purpose of this drill is to strengthen security and its foundations in the region, and to expand multilateral cooperation between the three countries to jointly support world peace, maritime security and create a maritime community with a common future," the Iranian official told ISNA. Both navies from Iran's armed forces and Revolutionary Guards will take part in the drills, which include various tactical exercises such as rescuing a burning vessel, releasing a hijacked vessel, and shooting at air targets at night.

Our sedentary lives really hit home for many people over the last year. Did you gain the COVID-19, or was it 20 pounds?......If you’re a gardener, you know gardening is exercise. Experts say the various activities and tasks of gardening ultimately use all of the major muscle groups. In addition, strenuous gardening activities such as raking, hoeing, and digging are both aerobic and muscle strengthening.Need to pick something up? Do your squats. Carrying something? Do some curls. Reaching for something? Calf raises. Do your rows while weeding. You get the picture. You’re incorporating typical gym exercises while you garden. No...

CHARLOTTE, N.C. — A “realistic” guerrilla war will be fought across two dozen North Carolina counties in the coming weeks, with young soldiers battling seasoned “freedom fighters,” according to the U.S. Army. The two-week “unconventional warfare exercise” will be staged Jan. 22-Feb. 4 on privately owned land. And it will be realistic enough to include the sounds of gunfire (blanks) and flares, the U.S. Army John F. Kennedy Special Warfare Center and School said in a news release. Exact times, locations and exercise specifics were not provided. However, advance publicity is intended to make sure civilians — including law enforcement...

* Researchers at the University of California-Riverside published results of a study that analyzed donated brain samples.* They focused on the form of tau proteins, which can be either right-handed or left-handed.* Researchers discovered that those who had a “different handed” form of tau proteins along with brain plaque and tangles also had dementia. Scientists in California tried to study Alzheimer’s disease from a different perspective and the results may have led them to the cause of the disease. Researchers at the University of California- Riverside (UCR) recently published results from a study that looked at a protein called...

New research published in the journal Proceedings of the National Academy of Sciences found that humans evolved to maintain a high degree of activity as we age. Some people think they need to rest more as they get older, but the opposite is actually true: cycling, strength training, yoga, hiking, and swimming are among activities that are ideal for seniors.Although humans might be tens of thousands of years past the hunter-gatherer days, the forces that shaped health for them are just as valid now, according to new research in the journal Proceedings of the National Academy of Sciences. One major...

Forget bedrest, research from Edith Cowan University (ECU) has shown exercise may be a key weapon in cancer patients' battle against the disease. Exercise causes muscles to secrete proteins called myokines into our blood—and researchers from ECU's Exercise Medicine Research Institute have learned these myokines can suppress tumor growth and even help actively fight cancerous cells. A clinical trial saw obese prostate cancer patients undergo regular exercise training for 12 weeks, giving blood samples before and after the exercise program. Researchers then took the samples and applied them directly onto living prostate cancer cells. Study supervisor Professor Robert Newton said...

New research has found that fruit and vegetable consumption and exercise can increase levels of happiness. While the link between lifestyle and wellbeing has been previously documented and often used in public health campaigns to encourage healthier diets and exercise, new findings published by the Journal of Happiness Studies show that there is also a positive causation from lifestyle to life satisfaction. This research is the first of its kind to unravel the causation of how happiness, the consumption of fruit and vegetables and exercising are related, rather than generalizing a correlation. The researchers used an instrumental variable approach to...

FDA approves drug to treat smallpoxDisease considered eradicated in 1980 but drug development for smallpox is an important component for medical countermeasure response [6/4/2021] The U.S. Food and Drug Administration today approved Tembexa (brincidofovir) to treat smallpox. Although the World Health Organization declared smallpox, a contagious and sometimes fatal infectious disease, eradicated in 1980, there have been longstanding concerns that the virus that causes smallpox, the variola virus, could be used as a bioweapon. Before its eradication in 1980, the variola virus mainly spread by direct contact among people. Symptoms typically began 10 to 14 days after infection and included...

Dr. Anthony Fauci, the White House’s chief medical adviser, said Wednesday (April 28) that the new outdoor mask recommendations from the Centers for Disease Control and Prevention (CDC) should motivate people to get vaccinated. The CDC said Tuesday that fully vaccinated Americans did not need to cover their faces outdoors unless they were in crowds, and that they could enjoy activities such as exercising outside and eating outdoors at restaurants without masks.