Exercise shown to release protein reducing bowel cancer risk (Releases IL-6 from 30 min of moderate exercise)

Medical Xpress / Newcastle University / International Journal of Cancer ^ | Apr. 7, 2022 | Samuel T. Orange et al

[ConservativeMind]

Scientists at Newcastle University have shown that physical activity causes the cancer-fighting protein, interleukin-6 (IL-6), to be released into the bloodstream which helps repair the DNA of damaged cells.

The findings, published in the International Journal of Cancer, sheds new light on the importance of moderate activity in the fight against the life-threatening illness and could help develop treatments in the future.

Repairing DNA

Dr. Sam Orange, Lecturer in Exercise Physiology at Newcastle University, said: "Previous scientific evidence suggests that more exercise is better for reducing bowel cancer risk as the more physical activity people do, the lower their chances of getting it. Our findings support this idea.

"When exercise is repeated multiple times each week over an extended period, cancer-fighting substances—such as IL-6—released into the bloodstream have the opportunity to interact with abnormal cells, repairing their DNA and reducing growth into cancer."

The participants cycled on indoor bikes for a total of 30-minutes at a moderate intensity.

They identified that blood samples collected straight after exercise slowed the growth of the cancer cells compared with those collected at rest.

Furthermore, as well as reducing cancer growth, the exercise blood samples reduced the extent of DNA damage, suggesting that physical activity can repair cells to create a genetically stable cell type.

Dr. Orange said: "Our findings are really exciting because they reveal a newly identified mechanism underlying how physical activity reduces bowel cancer risk that is not dependent on weight loss.

It is estimated that physical activity reduces the risk by approximately 20%.

[ConservativeMind]

This works to reduce the threat of cancer and to fight cancer you already have.

[ConservativeMind]

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[BipolarBob]

NO!! Not exercise! Anything but that. Give me a pill. Something.

[icclearly]

As a cancer patient I can say I totally agree! I was diagnosed with a rare form of lymphoma (blood cancer) in early 2014. I was treated and went into remission. This type of cancer normally returns in 24 to 36 months. I was a runner before the diagnosis but was no longer able to run. But I walk 3 to 5 miles a day - every day.

So here I am over eight years from diagnosis and remain in remission. Along with other lifestyle changes I firmly believe exercise has kept me going when my remission should have ended years ago.

Keep on walking!

[jonrick46]

Approximately how much time does it take to do a three mile walk?

[icclearly]

“Approximately how much time does it take to do a three mile walk?”

I live in a fairly hilly area and my average pace is around 18 minutes per mile. Some days 17 others 19. So, it takes about an hour. Thanks to the magic of cell phones I get caught up on my phone calls and some reading so it is not dead time.