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Keyword: doubleprion

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  • These Scientists Want to Redefine Alzheimer's as a 'Double-Prion' Disease

    05/03/2019 8:16:02 PM PDT · by BenLurkin · 16 replies
    gizmkodo ^ | Ed Cara
    Researchers this week say their work should upturn the conventional narrative of how Alzheimer’s disease happens. They argue the progression of Alzheimer’s is driven by a very specific form of two proteins that play a crucial role in the disease, and these forms should be considered prions—potentially infectious proteins that self-replicate by turning their brethren into a misfolded version of themselves. To put it simply, people with Alzheimer’s disease have brains that are filled with rigid, clumped-together deposits of the proteins amyloid beta and tau, called plaques and tangles, respectively. It’s long been assumed that if we can stop these...