Keyword: breastcancer
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The new figures come after the tragic death of Girls Aloud star Sarah HardingThree weeks after Girls Aloud singer Sarah Harding’s death, new figures have revealed how long people in Cambridgeshire are waiting for breast cancer treatment. NHS targets say most people urgently referred by their GP for suspected breast cancer should see a specialist within 14 days. Once they have been diagnosed, patients should start treatment within two months (62 days) of being referred. However, many people in England with suspected breast cancer are not being assessed and treated within these timescales – with chances of being seen quickly...
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Lack of FDA support amid "changes in the treatment landscape" cited in decisionGenentech announced that it will voluntarily withdraw its accelerated approval of the PD-L1 inhibitor atezolizumab (Tecentriq), in combination with nab-paclitaxel (Abraxane), for metastatic PD-L1-positive triple-negative breast cancer (TNBC). The decision was made despite a vote of support by an FDA advisory committee to maintain the accelerated approval in the absence of compelling data to support the results that led to the conditional approval. Since that committee meeting, the company discussed possible postmarketing research requirements (PMR) with the FDA, but "due to changes in the treatment landscape, the FDA...
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Researchers have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease. In normal breast development, estrogen stimulates and androgen inhibits growth at puberty and throughout adult life. Abnormal estrogen activity is responsible for the majority of breast cancers, but the role of androgen activity in this disease has been controversial. Androgens were historically used to treat breast cancer, but knowledge of hormone receptors in breast tissue was rudimentary at the time and the treatment's efficacy misunderstood. Androgen therapy was discontinued due to virilising side effects and...
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Vitamin D has a host of health benefits, however, new research suggests that there's another reason you should at least consider taking a supplement. According to a new study that was highlighted at the American Society of Clinical Oncology 2021 virtual annual meeting, having sufficient vitamin D levels is associated with an increased likelihood of surviving breast cancer. Researchers measured vitamin D levels at the time of breast cancer diagnosis in nearly 4,000 people and then survival outcomes a decade later. "Our study shows that patients who had sufficient vitamin D levels at the time of diagnosis—blood concentration of at...
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Ingredients found in hair dye and anti-ageing cream could delay breast cancer progression by two years, scientists believe. Early research suggests they boost the effectiveness of radiotherapy when injected into a tumour before treatment. The cocktail of hydrogen peroxide, which bleaches hair, and hyaluronic acid, which moisturises skin, costs less than £100....
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Conceptual illustration of breast cancer cells. (MedicalRF.com/Getty Images) Researchers in Australia have discovered a gene responsible for a particularly aggressive type of hormone-sensitive breast cancer which has tragically low survival rates. "Hopefully this will dramatically improve the poor outcomes these patients currently suffer," said Harry Perkins Institute of Medical Research epigeneticist Pilar Blancafort. It's hard to overstate just how different cancers can be from one another. Even under the umbrella of 'breast cancer' lie several types, such as hormone receptor sensitive, HER2 positive, or non-hormone sensitive breast cancer; within those groups, there are even more types that can respond to...
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SYDNEY (AFP) - Australian scientists have discovered pineapple molecules can act as powerful anti-cancer agents and said the research could lead to a new class of cancer-fighting drugs. Scientists at the Queensland Institute of Medical Research (QIMR) said their work centred on two molecules from bromelaine, an extract derived from crushed pineapple stems that is used to tenderise meat, clarify beers and tan hides. One of the molecules, CCZ, stimulates the body's immune system to target and kill cancer cells, the other, CCS, blocks a protein called Ras, which is defective in 30 percent of all cancers. QIMR researcher Tracey...
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On Tuesday night, during a montage of women who have served in both the Trump administration and campaigns, the anti-Trump phony conservative Lincoln Project tweeted that “Kayleigh McEnany is the first ghoul to serve as Press Secretary.” They deleted it only a minute later. This happened just the day after the group deleted another tweet claiming that an RNC audience member yelled “monkey” in reference to former President Barack Obama, which would’ve been an obvious racial slur. Even though the audio clearly said “spygate,” the phony “principled conservatives” still accused President Trump of enjoying the non-existent insult. While claiming to...
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Actress Kelly Preston has died following a two-year battle with breast cancer, husband John Travolta said in a social media post. She was 57. "It is with a very heavy heart that I inform you that my beautiful wife, Kelly, has lost her two-year battle with breast cancer," Travolta wrote Sunday in an Instagram post. "She fought a courageous fight with the love and support of so many." The actor praised doctors and nurses at MD Anderson Cancer Center in Houston as well as Preston's "many friends and loved ones who have been by her side." "Kelly's love and life...
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**Numerous companies are pursuing various COVID-19 vaccine strategies with great urgency. **At least until widespread availability and acceptance of a safe and effective vaccine, the search for a therapeutic is of critical moment. **CytoDyn's leronlimab is shaping up as a prime contender to be a preferred COVID-19 therapeutic. **To this point, leronlimab has a pristine safety profile; and CytoDyn has leronlimab's manufacturing component under control. **At this point during the start of summer 2020, the world has a huge catalog of unproven COVID-19 vaccines in early development, some in phase 2, more in phase 1, most have yet to reach...
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GREELEY, Colo. (CBS4) – A team of scientists at the University of Northern Colorado believe venom from venomous snakes could carry the cure to cancer. Dr. Stephen Mackessy, professor at UNC’s School of Biology, says studies show venoms in different snakes can attack human cancer cells in unique ways. (credit: CBS) To conduct the study, Mackessy’s students are given access to hundreds of snakes from around the world, all of which are stored in a secured facility on the campus of UNC. From rattlesnakes to vipers, the students are able to extract venom from each snake to study the compounds...
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The T-shirts read "Fight like a girl." But while October’s Breast Cancer Awareness Month brings messages of strength and familiar pink ribbons, a fight rages on for the disease's lesser-known victims: men. Though breast cancer strikes men much less often than women, a new study in the Journal of the American Medical Association [JAMA] reveals that three to five years after a breast cancer diagnosis, men are less likely to be alive.
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Researchers have been able to coax human breast cancer cells to turn into fat cells in a new proof-of-concept study in mice. To achieve this feat, the team exploited a weird pathway that metastasising cancer cells have; their results are just a first step, but it's a truly promising approach. When you cut your finger, or when a foetus grows organs, the epithelium cells begin to look less like themselves, and more 'fluid' – changing into a type of stem cell called a mesenchyme and then reforming into whatever cells the body needs. This process is called epithelial-mesenchymal transition (EMT)...
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A method for fooling breast cancer cells into fat cells has been discovered by researchers from the University of Basel. The team were able to transform EMT-derived breast cancer cells into fat cells in a mouse model of the disease – preventing the formation of metastases. The proof-of-concept study was published in the journal Cancer Cell. Malignant cells can rapidly respond and adapt to changing microenvironmental conditions, by reactivating a cellular process called epithelial-mesenchymal transition (EMT), enabling them to alter their molecular properties and transdifferentiate into a different type of cell (cellular plasticity). Senior author of the study Gerhard Christofori,...
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In February 2017, the Asia-Pacific Journal of Clinical Oncology published the “Epidemiology of breast cancer in Indian women.” Malvia, et al. found that from 1982-2005, the incidence of breast cancer had almost doubled. Breast cancer is now the leading cause of cancer deaths in women in India. India’s burden of breast cancer is ever increasing and now impacting 1.5 million women a year. Moreover women suffering from breast cancer were a decade younger than women in western countries. Most breast cancers in India occur in women in their 30s and 40s! Link to abortion In 2018, the Breast Cancer Prevention...
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Every time I work up a good sweat, I feel like my cancer cells are sweating, too. Over the past 7 years, running has been a constant for me. I ran cross country in middle school, but quit because I didn’t think I was good enough (silly me!). I’ve always been into fitness and ran casually in college, but it wasn’t until 2011 that I really buckled down and started running consistently. I ran my first marathon in 2012, and since then, I’ve run over 40 marathons and ultras. In fact, in September, I completed the Northcoast 24-Hour Endurance Run....
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Actress and director Sondra Locke, who received a supporting actress Oscar nomination in her first movie role for “The Heart is a Lonely Hunter,” died Nov. 3 at 74. The Los Angeles County Public Health Department confirmed her death. She died due to breast and bone cancer, according to Radar Online, which reported that she was laid to rest at Pierce Brothers Westwood Village Memorial Park & Mortuary. Locke had a contentious relationship of more than a decade with Clint Eastwood, who first cast her in “The Outlaw Josey Wales.”
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Link Only https://www.bloomberg.com/news/articles/2018-06-04/billions-of-fighting-cells-clear-woman-s-breast-cancer-in-study
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MIT biologists have designed a new peptide that can disrupt a key protein that many types of cancers, including some forms of lymphoma, leukemia, and breast cancer, need to survive. The new peptide targets a protein called Mcl-1, which helps cancer cells avoid the cellular suicide that is usually induced by DNA damage. By blocking Mcl-1, the peptide can force cancer cells to undergo programmed cell death. "Some cancer cells are very dependent on Mcl-1, which is the last line of defense keeping the cell from dying. It's a very attractive target," says Amy Keating, an MIT professor of biology...
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Danish researchers have found there are approximately 13 additional breast cancer cases for every 100,000 women who use hormonal contraception for one year. Women who use hormonal birth control pills and other forms of contraceptives have a small but increased risk of developing breast cancer, a new study from Denmark has found — the latest in a string of dangerous side-effects researchers have discovered about the risks of hormonal contraceptives. The study, published in the New England Journal of Medicine, followed 1.8 million Danish women for an average of more than 10 years. Of those women, researchers identified 11,517 cases...
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