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Triple-negative breast cancer (TNBC) is among the most aggressive types of breast cancer. Despite initial responsiveness, many patients experience rapid relapse driven by cancer stem-like cells that survive chemotherapy and seed metastasis. Addressing this unmet need, researchers have discovered that pitavastatin, a widely prescribed cholesterol-lowering drug, can directly inhibit the anti-apoptotic protein Mcl-1, a key driver of survival, stemness, and paclitaxel resistance in TNBC cells, thereby preventing distant metastasis. The team found that pitavastatin binds specifically to the BH3-binding groove of Mcl-1, disrupting its stability and inducing mitochondrial dysfunction. This inhibition triggered a cascade of mitochondrial damage, leading to ROS...

The technique, known as IORT, has numerous benefits, surgeons say, but it generates less money for hospitals and radiation oncologists.It’s not uncommon for breast cancer patients in the rural South to travel hundreds of miles to reach the medical practice run by Dr. Phillip Ley, a cancer surgeon in Jackson, Mississippi. For those who are good candidates, Ley recommends a therapy that delivers a single, targeted radiation dose to a patient’s breast tissue immediately after surgery to remove a tumor. Known as intraoperative radiation therapy, or IORT, it costs patients less in both time and money than traditional radiation treatments,...

A Chinese doctor was busted at a Texas airport for allegedly attempting to smuggle US-funded cancer research back to his home country – and could face federal charges for the brazen theft. Yunhai Li, 35, was nabbed at George Bush Intercontinental Airport in Houston on July 9 after border patrol discovered the sensitive confidential medical records on his laptop during an inspection ahead of his flight to China, the Harris County District Attorney’s Office announced Monday. The Chinese national, who was employed as a researcher at MD Anderson Cancer Center since 2022, was reportedly working on a vaccine to prevent...

A new study has found that a commonly prescribed anti-nausea medication is associated with a better prognosis for women with early-stage breast cancer, particularly triple-negative breast cancer. The research team evaluated Cancer Registry of Norway data of 13,811 women diagnosed with early-stage breast cancer between 2008 and 2020 who received both chemotherapy and anti-nausea medications that are used to prevent chemotherapy-induced nausea and vomiting. In women with breast cancer, the use of the anti-nausea medication aprepitant during chemotherapy treatment was linked to an overall 11% lower risk of developing cancer recurrence and 17% lower risk of breast cancer-related death in...

The most common cancer in women — and one of the deadliest — may have finally met its match. Development of a breakthrough vaccine researchers say could eradicate breast cancer by 2030 wrapped up phase one of its clinical trial this week, with more than 75% of women showing a strong immune response, as measured by antibodies on their white blood cells. The vaccine is aimed at both preventing and treating breast cancer — which affects one in eight women. “It’s very exciting,” said Dr. Amit Kumar, CEO of Anixa Biosciences, which is designing the vaccine along with the Cleveland...

My friend, the late Anna Rumaderun, was a young Indonesian woman totally dedicated to friendship with The West based on the bonds of history forged in World War Two. Like me she had huge respect for General Douglas MacArthur. She trusted traditional medicine and died from breast cancer. She was terrified of modern medicine because two of her friends died post mastectomy. She leaves behind a husband with movie star good looks and a six year old little boy named after me. Rest In Peace, Anna. We miss you deeply. We know you ARE WITH GOD.

Presented at ESTRO 2025 in Vienna, Austria, a 10-year study involving over 4,000 UK patients confirms that a one-week course of post-surgery radiotherapy is just as safe and effective as the traditional three-week regimen for early-stage breast cancer patients. These long-term results from the FAST-Forward trial could further reduce the burden on breast cancer patients worldwide, and expand access to life-saving radiotherapy. The phase III randomized trial followed up patients for ten years and showed that a shorter, five-day radiotherapy schedule provides a similar level of cancer control as the standard 3-week treatment, without additional long-term side effects. This builds...

Fox host Kat Timpf reveals shock cancer diagnosis after giving birth to first baby By RACHEL BOWMAN FOR DAILYMAIL.COM Published: 16:43 EST, 25 February 2025 | Updated: 17:32 EST, 25 February 2025 e-mail 59 shares 90 View comments Fox News star Kat Timpf revealed she was diagnosed with breast cancer just hours before giving birth to her first child. The 36-year-old remained on the air well into her third trimester, and recently shared some of the most sickening comments she's received from viewers about her baby bump. Timpf announced she delivered her son last week in a shocking Instagram post...

A clinical trial has shown adding an immunotherapy drug to the chemotherapy that patients receive ahead of surgery can dramatically improve breast cancer cure rates. The Phase III CheckMate-7FL trial involved 510 people with the "ER+/HER2-"sub-type which accounts for around 70% of all breast cancers. These patients receive chemotherapy to shrink their tumor, making it easier to surgically remove. This trial assessed adding an infusion of the drug nivolumab—or a placebo—to the pre-surgery phase and then assessing how patients respond overall, and the practice changing results have been published. Professor Sherene Loi said adding nivolumab led to around a doubling...

Virologist Beata Halassy says self-treatment worked and was a positive experience — but researchers warn that it is not something others should try.Viruses such as measles (pictured here) can be used to attack cancerous cells. Credit: Eye Of Science/Science Photo Library A scientist who successfully treated her own breast cancer by injecting the tumour with lab-grown viruses has sparked discussion about the ethics of self-experimentation. Beata Halassy discovered in 2020, aged 49, that she had breast cancer at the site of a previous mastectomy. It was the second recurrence there since her left breast had been removed, and she...

Breast cancer is one of the most common cancers in women, with high rates of mortality and morbidity. According to a study, scientists have revealed a new function of ganoderic acids from Ganoderma lucidum (G. lucidum) for treating breast cancer. This is the first time scientists identified potential targets of ganoderic acids for breast cancer treatment using bioinformatics techniques. G. lucidum, also called as Lingzhi in Chinese, is a popular medicinal fungus. It has a unique therapeutic and pharmacological reputation in suppressing cancer/tumor progression, especially breast cancer, due to its embedded rich bioactive chemical constituents, mainly triterpenoids (ganoderic acids). In...

In the past 10 years breast cancer has risen 1.4 percent in white under-50s, compared to 0.7 percent in over-50s, or double the rate. Olivia Munn is among the women in their 40s to have been diagnosed with the disease, after revealing in March that she was diagnosed with the cancer last year at the age of 43 years — just two months after a mammogram said she was all clear. The report, published this week, found that about 310,700 women are diagnosed with breast cancer every year. Of these, an estimated 13,180, about four percent, are under 40 years...

A study led by investigators found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment—particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70–80% of all breast cancer cases. In preclinical experiments, researchers found: —Manuka honey significantly reduced tumor growth in mice with ER-positive breast cancer cells by 84% without affecting normal breast cells or causing major side effects. —Higher concentrations of Manuka honey led to a greater reduction in cancer cell growth. —Manuka honey reduced levels of signaling pathways that are upregulated in...

WASHINGTON — Sheila Jackson Lee, a Houston Democrat who was one of the longest serving members of Texas’ Congressional delegation and a longtime advocate for progressive causes, died on Friday amid her battle with pancreatic cancer. She was 74. Jackson Lee began her congressional career as an underdog, defeating four-term U.S. Rep. Craig Washingtonin the 1994 Democratic primary, before establishing herself as a fixture in Congress and Houston with ties to the highest reaches of the Democratic Party. Jackson Lee was a progressive fixture on Capitol Hill for decades. She was an early opponent of the Iraq War and advocate...

U.S. Representative Sheila Jackson Lee, a long-serving Democrat from Texas, has passed away at the age of 74. * * * The Gateway Pundit reported in June that Jackson Lee had been diagnosed with pancreatic cancer.

Rep. Sheila Jackson Lee, D-Texas, has died at the age of 74 after a battle with cancer, her family announced on Friday. "Today, with incredible grief for our loss yet deep gratitude for the life she shared with us, we announce the passing of United States Representative Sheila Jackson Lee of the 18th Congressional District of Texas," her family said in a statement. “A local, national, and international humanitarian, she was acknowledged worldwide for her courageous fights for racial justice, criminal justice, and human rights, with a special emphasis on women and children,” the statement said. Jackson Lee announced in...

Rep. Sheila Jackson Lee (D-Texas), who served in Congress for nearly three decades, has died at the age of 74, her family announced Friday evening. “Today, with incredible grief for our loss yet deep gratitude for the life she shared with us, we announce the passing of United States Representative Sheila Jackson Lee of the 18th Congressional District of Texas,” her family wrote in a statement shared to her account on X. Her family did not specify a cause of death, but the news comes just over one month after the Congresswoman revealed that she had been diagnosed with pancreatic...

BREAKING 🚨🚨 Representative Sheila Jackson Lee has died.

Shannen Doherty, best known for her iconic roles in “Beverly Hills, 90210” and “Charmed,” has passed away at 53 after a prolonged battle with breast cancer. Doherty’s publicist, Leslie Sloane, confirmed the sad news in a statement to PEOPLE on Sunday, expressing, “It is with a heavy heart that I confirm the passing of actress Shannen Doherty.”

Metformin is a widely prescribed drug for managing type 2 diabetes. In recent years, indications of its potential anticancer properties have emerged in research. A study has found that metformin activates the body's immune cells. The effect was particularly observed in what are known as dendritic cells, which are the most effective in helping the immune system identify cancer cells as foreign entities. "Our study found that metformin contributed to the metabolism of dendritic cells so that they became active and enhanced the immune response against cancer cells," says Rita Turpin. Identifying this effect can help to develop anticancer therapies...