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I remember being a kid and seeing my grandmother without her dentures for the first time. It was a harrowing experience. Now my dad has dentures so, genetically speaking, I’m several decades out from needing some myself. However, it’s possible that modern medicine will solve the issue of lost teeth by then, thanks to a new drug that's about to enter human trials. The medicine quite literally regrows teeth and was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital....

The world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030. The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar. The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side...

The world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030. The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar. The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side...

Researchers in Japan are currently working on a medication that would allow people to grow a new set of teeth, with a clinical trial slated for July 2024.

he mRNA vaccines were released globally in early 2021 with the slogan ‘safe and effective.’ Unusually for a new class of medicine, they were soon recommended by public health authorities for pregnant women. By late 2021, working-age women, including those who were pregnant, were being thrown out of employment for not agreeing to be injected. Those who took the mRNA vaccines did so based on trust in health authorities – the assumption being that they would not have been approved if the evidence was not absolutely clear. The role of regulatory agencies was to protect the public and, therefore, if...

The Food and Drug Administration on Monday significantly restricted the use of a pair of monoclonal antibody treatments for COVID-19 because they are ineffective against the omicron. The agency said the therapies made by Eli Lilly and Regeneron should only be used in patients that have been infected with or exposed to a variant that is susceptible to the treatments.

In case you doubted my original report of the Utah Department of Health survey re. eligibility for monoclonal antibody treatment favoring minorities, I submit this:In New York, racial minorities are automatically eligible for scarce COVID-19 therapeutics, regardless of age or underlying conditions. In Utah, "Latinx ethnicity" counts for more points than "congestive heart failure" in a patient’s "COVID-19 risk score"—the state’s framework for allocating monoclonal antibodies. And in Minnesota, health officials have devised their own "ethical framework" that prioritizes black 18-year-olds over white 64-year-olds—even though the latter are at much higher risk of severe disease. – Washington Free BeaconI recall...

“Monoclonal Antibody Treatments Save Lives,” announced the New York City Department of Health in an October 26 public notice. These treatments “are available and lifesaving,” the agency said, noting that they “have averted at least 1,100 hospitalizations and at least 500 deaths among people treated in New York City.” The agency urged the public to seek out these monoclonal antibody treatments as soon as possible: “When given early after symptom onset, mAb treatments can decrease the risk of hospitalization and death due to COVID-19, which is why it is crucial to get tested for COVID-19 as soon as symptoms begin...

Dr. Ron Elfenbein called the pause in some antibody treatments the 'height of bureaucratic arrogance'.. A doctor in Maryland said he had to cancel potentially life-saving monoclonal antibody infusions for about 250 people over the last week after the federal government stopped distributing treatments made by Regeneron and Eli Lilly because they aren't effective against omicron, even though the delta variant, which the drugs are effective at treating, was still dominant at the time. The Office of the Assistant Secretary for Preparedness and Response halted the allocation of those two antibody treatments last Thursday amid the rise of omicron, which...

Dec 8 (Reuters) - The U.S. Food and Drug Administration on Wednesday authorized the use of AstraZeneca's (AZN.L) antibody cocktail to prevent COVID-19 infections in individuals with weak immune systems or a history of severe side effects from coronavirus vaccines.

Chinese scientists claim to have isolated an antibody which can effectively neutralize all strains of Covid-19, referencing both lab experiments and those performed on a living organism. In a study published on Tuesday, Chinese scientists from a variety of institutions, including Sun Yat-sen University in Guangzhou and Zhejiang University in Hangzhou, suggested that they may have the panacea to the Covid-19 pandemic.

Scientists have identified an antibody that can protect people from COVID-19, its variants and other types of coronaviruses.... It is effective at both preventing infection and at helping treat a person that has already contracted Covid. The research team at the University of North Carolina - Chapel Hill (UNC) and Duke University, in Durham, says it believes it has found a key piece that can help combat the current pandemic and future virus outbreaks.

AstraZeneca, the drugmaker that developed one of the first COVID-19 vaccines, has asked the U.S. Food and Drug Administration to authorize the emergency use of a first-of-a-kind antibody treatment to prevent the disease. The Anglo-Swedish company said Tuesday that the treatment, known as AZD7442, would be the first long-acting antibody combination to receive an emergency authorization for COVID-19 prevention. If authorized, the drug would likely be limited to people with compromised immune systems who don’t get sufficient protection from vaccination. “First and foremost we want to protect those vulnerable populations that haven’t been adequately protected by the vaccine,” said Menelas...

What this study finds is exactly what vaccine developer Geert Vanden Bossche (Belgium) has been predicting. The predominance of antibody-resistant SARS-CoV-2 variants in vaccine breakthrough cases from the San Francisco Bay Area, California. [DATA LINK HERE]The California study finds that vaccinated individuals are more susceptible to COVID variant infections than unvaccinated. Geer Vanden Bossche has been warning that vaccine antibodies would suppress natural antibody responses. The vaccine antibodies take control of the immune system and defend only against a targeted virus.Among vaccinated individuals, a COVID variant virus is not recognized by the specialized antibodies provided by the vaccine, and the...

I recently had a COVID19 antibody test performed by Labcorp. The result was positive for SARS-CoV-2 antibodies with a "Semi-Quant Total Ab" of 506.8 U/ml. And there's the rub...what does this mean? Is it good, bad or indifferent? The report doesn't say and my PCP says there no data available yet that would allow him to grade the result. I am hoping that someone out there in Freeper land can explain how this number (506.8) correlates to protection. Thanks in advance.

It neutralized the coronavirus behind the first SARS outbreak, too. newly discovered antibody was able to neutralize not only all strains of COVID-19, but other coronaviruses known to cause respiratory infections in humans — a potential silver bullet for a whole class of deadly, flu-like viruses. Mutant viruses: As viruses spread, they undergo tiny genetic mutations, and when we find a unique version of the virus, we call it a new strain. Occasionally, new strains appear that can spread more easily, evade the immune system, or cause more severe disease. Several worrisome strains of COVID-19 have already appeared during the...

Sotrovimab, the newest antibody therapy, was developed by GlaxoSmithKline and Vir Biotechnology after a large collaborative study by scientists from across the nation discovered a natural antibody (in the blood of a SARS survivor, back in 2003) that has remarkable breadth and efficacy. Experiments showed that this antibody, called S309, neutralizes all known SARS-CoV-2 strains – including newly emerged mutants that can now “escape” from previous antibody therapies – as well as the closely related original SARS-CoV virus. Jay Nix, leader of the Molecular Biology Consortium based at Berkeley Lab’s Advanced Light Source (ALS), used beamlines at the ALS and...

A George Mason University law professor with naturally acquired immunity from COVID is fighting against his employer’s strict COVID vaccine mandate. Antonin Scalia Law School Professor Todd Zywicki, who recovered from a bout with COVID and has blood tests showing antibodies to the virus, said he will not agree to the university’s policy that employees get the vaccine or face numerous sanctions. “George Mason is forcing me to choose between serving my students on one hand and undergoing an unnecessary and potentially risky medical procedure on the other,” Zywicki said in a statement. “Multiple clinical studies have shown that natural...

Note: link is to the general descrption of the test, not my results. My results follow: COVID-19 Antibody Test (SARS-CoV-2 AB IgG), Semi-Quantitative POSITIVE Current Result 1.25 index <1.00 Negative > or = 1.00 Positive I took this IgG test at the end of April and it was negative, took it 16 days after the J&J shot and it was still negative https://freerepublic.com/focus/f-chat/3965215/posts Took it again 14 days later (30 days after J&J) and it is finally positive. That means a detectable level of antibodies to the spike protein.

The UK RECOVERY trial investigators recently disclosed that Regeneron’s REGEN-COV, a pair of monoclonal antibodies, actually reduced the risk of death by 20% in patients hospitalized with COVID-19 who failed to sustain their own immune response. According to the company’s press release, this monoclonal antibody cocktail represents the first antibody treatment that improved survival in patients hospitalized with COVID-19. The company will not only share this data with regulatory authorities immediately but will also seek to expand its U.S. EUA to include appropriate hospitalized patients.TrialSite provides a brief summary breakdown of this most recent information generated by the UK RECOVERY...