Posted on 08/26/2021 9:50:06 AM PDT by BenLurkin
Sotrovimab, the newest antibody therapy, was developed by GlaxoSmithKline and Vir Biotechnology after a large collaborative study by scientists from across the nation discovered a natural antibody (in the blood of a SARS survivor, back in 2003) that has remarkable breadth and efficacy.
Experiments showed that this antibody, called S309, neutralizes all known SARS-CoV-2 strains – including newly emerged mutants that can now “escape” from previous antibody therapies – as well as the closely related original SARS-CoV virus.
Jay Nix, leader of the Molecular Biology Consortium based at Berkeley Lab’s Advanced Light Source (ALS), used beamlines at the ALS and beamlines at SLAC’s Stanford Synchrotron Radiation Lightsource to perform X-ray crystallography on samples of survivor-derived antibodies during an early phase of the study. His work, alongside other crystallography and cryo-electron microscopy findings, helped generate detailed structural maps of how these antibodies bind to the SARS-CoV-2 spike protein, allowing the wider team to select the most promising contenders and advance them to cell culture- and animal-based studies. Following exciting lab results, the developers designed sotrovimab based on the structure of S309, and evaluated it in clinical trials.
The FDA granted an EUA for sotrovimab in late May after trials showed that people with mild to moderate COVID-19 infections who received an infusion of the therapy had an 85% reduction in rates of hospitalization or death, compared with placebo.
(Excerpt) Read more at scitechdaily.com ...
I hope this one works out.
The Death Gnome will not be happy ... unless he can find a way to get his fingers in the $$ pie.
Finally, some good news on the Covid front. At least it sounds like good news. Hopefully this treatment will achieve widespread use if it is as good as this article claims. But the medical and political establishments will probably find some excuse to ignore it or downplay it, maybe even ban it. They are all caught up in the “vax everyone” frenzy; it serves their lust for power and control.
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Since fully half of studies end up being complete fraud I’ll withhold judgement.
Most “miracle “ drugs end up being pulled from the market.
Anything promising will be shut down and ridiculed by the vaxx cult.
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This sounds like an alternative monoclonal treatment to Regeneron if I scanned the article correctly. Is it as good or better, I wonder.
I will believe it when I see it. Furthermore, if it actually works, doctors won’t be allowed to use it.
Cuomo Will Ban it in ny before he is fully out of his job
sotrovimab
Where do companies come up with drug names?
He’s gone I believe
The b,urban says uts used on mild to moderate infecfion tomkeep,to keep, out of hospitals, the ones you mentioned I thi k are used after someone is admitted with moderate to severe?
Coming up with unique names in the commercial space is always a chore...mostly to keep the lawyers at bay.
I’ve noticed that the suffix “mab” seems to correspond to monoclonal antibody therapies of various sorts.
Thanks for posting; ping to article!
Do they ever truly leave? (Think Susan Rice and ilk)
But since it will not further depopulation efforts, it will not see the light of day.
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