The coronavirus quarantine has contributed to a surge in the demand for prescription tranquilizers and sleep aids in the United States, as Americans continue to feel on edge about the uncertainty of the disease, according to a new research report. The largest spike was in prescriptions for anti-anxiety drugs, which rose 34.1 percent from mid-February to mid-March, per the pharmacy benefit management organization Express Scripts. From February 16 to March 15, prescriptions for antidepressants rose 18.6 percent, while sleeping medications ticked up by 14.8 percent.