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Keyword: amodiaquine

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  • Human Organ Chips Shift Amodiaquine from Old Antimalarial to Promising COVID-19 Treatment

    05/04/2021 1:55:19 PM PDT · by RC one · 23 replies
    As the COVID-19 pandemic continues, the pace of vaccine development has surpassed anyone’s wildest expectations. Unfortunately, drug development for treatments has not kept the same pace. Indeed, there are still very few effective treatments for COVID-19. Now, a collaboration between four research institutes has identified the antimalarial drug amodiaquine as a potent inhibitor of SARS-CoV-2 infection in human lung cells and in living preclinical models. This breakthrough helped secure the inclusion of amodiaquine in a COVID-19 clinical trial that is currently underway in 13 different countries in Africa where this drug is inexpensive and widely available.The research is published in...