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First, my daughter came out as transgender; then my bisexual wife came out as nonbinary. As the only nonqueer person in the family, I often feel left out by their shared experience. But my queer family has taught me a lot about myself and how masculinity can be less restrictive. My 19-year-old daughter last month invited her mother to see the queer comedian Chris Fleming. My wife was thrilled. Our daughter still lives with us, but she often communicates in brief grunts as she scurries down to her basement lair, emerging only to let in friends and forage for chicken...

The Archdiocese of Portland has instructed Catholic schools in the area to rebuff what it calls “gender identity theory.” “This means that names, pronouns, facilities use, attire, and sports participation should depend upon biological sex identity, rather than self-perceived gender identity,” reads a 17-page document called “A Catholic Response to Gender Identity Theory” from Archbishop Alexander K. Sample late last month. The National Catholic Reporter wrote Feb. 2 that the Portland archdiocese is just the latest branch of the Catholic Church to enact similar policies, but it’s likely to face blowback from its schools, including those in Portland, given the...

Vladimir Putin is pulling mercenaries from Russia's notorious Wagner Group out of Ukraine over fears from the Kremlin that they are becoming 'too powerful', reports say. The squad, which consists of 50,000 troops, have been a key part of Russia's horrific invasion of Ukraine - fighting in the east of the war-torn nation. The Russian President, Putin, reportedly became more concerned about his own position before the demotion of Wagner, founded by Yevgeny Prigozhin - which recruits many convicted criminals - was ordered. Prigozhin has halted in the recruiting of prisoners and he will withdraw soldiers in the next few...

After a significant drop in student enrollment, officials from Washington's largest school district are floating the idea of shuttering some schools and cutting staff, the Seattle Times reported. School officials from Seattle Public Schools discussed the potential need to "consolidate into a system of well-resourced schools" because of significant budget shortfalls related to decreased student enrollment. The district's senior staff discussed how consolidating the district's 106 schools may provide students with improved access to specialized programs, social workers, specialists, counselors, and nurses. The district's interim deputy superintendent, Fred Podesta, argued that "consolidating into larger schools that have the resources they...

On Monday, Florida Governor Ron DeSantis announced legislation that would protect Floridians from banks from using Environmental, Social, and Governance (ESG) social credit scores in how they lend. DeSantis said ESG has become a "mechanism to inject political ideology into investment decisions, corporate governance, and really just the everyday economy," Florida's Voice reports.

Researchers found that a good fat derivative may be able to relieve symptoms in patients suffering from chronic inflammatory diseases, such as multiple sclerosis (MS). MS is a chronic, autoimmune disease of the brain and spinal cord during which the immune system attacks the cells and tissues that protect nerve fibers. There is no cure for MS. The researchers specifically looked at docosahexaenoyl ethanolamide (DHEA), a derivative of the lipids found in cold-water fish and fish oil supplements, and its impact on the immune system. Interestingly, DHEA has been shown to be anti-inflammatory and has similar properties to cannabis in...

ransomnote: Great little 2 minute 20 second video trailer on Twitter.The brilliant @0rf created a mini-documentary - entitled "The Typhoid Mary of Disinformation" - on how much @NicolleDWallace reflexively spreads lies. A million people have watched: https://rumble.com/v15xkey-nicolle-wallace-the-typhoid-mary-of-disinformation.htmlHere's the trailer. *This* is how disinformation spreads, and by whom:· Feb 12, 2023ransomnote: Full video on Rumble (26 minutes):Nicolle Wallace: "The Typhoid Mary of Disinformation"

Warning! This website contains detailed written instructions, photos, and videos about trapping, dispatching, skinning, and cooking squirrels. Content may not be appropriate for all audiences. Use discretion.

h/t to Red Badger Recently, a team of researchers from the Center for Multidimensional Carbon Materials within the Institute for Basic Science (IBS), South Korea led by Director Rodney Ruoff and his colleagues at the University of Science and Technology of China led by Professor Yanwu Zhu, reported a discovery of a new form of carbon. Zhu who led the USCT team said, “Professor Ruoff explained his interest in the triply periodic minimal surfaces that were described by the mathematician Schwartz, and how trivalently bonded carbon can in principle yield identical structures at the mathematical constructs. These are now referred...

Actor Austin Majors, a child star from the hit network cop drama “NYPD Blue” has died at the age of 27, Variety and TMZ report. Majors died Saturday night while staying at a homeless housing facility in Los Angeles. A source “with direct knowledge of the circumstances” told TMZ they believe Majors may have ingested a fatal amount of fentanyl. An autopsy was scheduled for Monday.

"When any one heareth the word of the kingdom, and understandeth it not, then cometh the wicked one, and catcheth away that which was sown in his heart. This is he which received seed by the way side. "But he that received the seed into stony places, the same is he that heareth the word, and anon with joy receiveth it; Yet hath he not root in himself, but dureth for a while: for when tribulation or persecution ariseth because of the word, by and by he is offended. "He also that received seed among the thorns is he that...

Solid state laser death ray. Be afraid. Be very afraid.

A photo of former Arizona Republican gubernatorial candidate Kari Lake attending Super Bowl LVII has gone viral, but for reasons you might not expect. The former news anchor turned GOP firebrand was seen sitting during the controversial playing of the Black national anthem ahead of the game, which took place Sunday at State Farm Stadium in Glendale, Arizona. A photo of her refusing to stand for the anthem was posted on social media and quickly sparked a frenzy of people praising her decision.

A romance novelist who once trademarked the word “cocky” was arrested after leading police on a high-speed chase through a Wyoming national park — but has been missing ever since her release from jail. Faleena Hopkins, 52, was arrested Jan. 27 after leading cops on a 24-mile pursuit through Grand Teton National Park that only ended when officers used spike strips to deflate her tires. While Hopkins is best known for her raunchy “Cocker brother” romance series that spans 22 titles, she also made national headlines in 2018 when she registered for and received a trademark on the word “cocky.”...

COVID-19 has led to increased focus on a disease with similar hallmarks and symptoms—myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Two studies are taking a closer look at ME/CFS as it relates to the microbiome and the metabolites that microbial species produce. Both studies found that ME/CFS is associated with reduced levels in the gastrointestinal microbiome of microbes known to produce the fatty acid butyrate. ME/CFS is a chronic, complex, and systemic disease associated with neurological, immunological, autonomic, and energy metabolism dysfunctions. It is believed in most cases to be triggered by exposure to viruses or other infectious agents. Oh's analysis showed...

Back in 2019, Democratic Minnesota Rep. Ilhan Omar issued an apology to the Jewish community. “Anti-Semitism is real and I am grateful for Jewish allies and colleagues who are educating me on the painful history of antisemitic tropes,” she said. “My intention is never to offend my constituents or Jewish Americans as a whole. We have to always be willing to step back and think through criticism, just as I expect people to hear me when others attack me for my identity. This is why I unequivocally apologize.” The congresswoman released the statement after she posted a tweet that suggested...

I am a budding options/futures trader with my own sole proprietor investment business. Heading into 2022, I took on a large cash infusion of $500,000 from friends and family under the guise of a promise I made to issue a 10% return on their money. This promise was made via a signed promissory note, and the return was less than the annual return I had been experiencing years before. And then 2022 happened. It was an extremely bad year for the markets, and the worst I’d seen since I had been actively trading. Needless to say, I was not able...

Farmington, N.M. has the fastest-rising housing costs in the United States, according to a new report from the National Association of Realtors scanning home prices across the nation. Communities in Florida and North Carolina took up seven of the top 10 metro areas with the fastest-growing home prices, with the North Port-Sarasota-Bradenton area coming in second. The report found that prices for single-family homes increased in nearly 90 percent of all metro areas, with the median price increasing by 4 percent from the same time last year to $378,700. The report looked at changes in housing prices in 186 metropolitan...

A senior Customs and Border Protection (CBP) source said that apprehensions of nationals from China are up 800% compared to the same period last fiscal year when including January — the numbers for which have not yet been released. The DHS is on the lookout for potential Chinese spies and other national security threats arriving at the southern border. The U.S. southern border is in the throes of a historic migrant crisis, with more than 251,000 migrant encounters in December

TP53 mutant head and neck squamous cell carcinoma (HNSCC) patients exhibit poor clinical outcomes with 50–60% recurrence rates in advanced stage patients. In a recent phase II clinical trial, adjuvant therapy with everolimus (mTOR inhibitor) significantly increased 2-year progression-free survival in p53 mutated patients. TP53-driven mTOR activation in solid malignancies causes upregulation of HIF-1α and its target, downstream effector VEGF, by activating STAT3 cell signaling pathway. In this recent study, Md Maksudul Alam investigated the effects of everolimus on the STAT3/HIF-1α/VEGF pathway in TP53 mutant cell lines and xenograft models. "The role of mTOR inhibitors (mTORi) as potent growth inhibitory...