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Inconsistencies With Neanderthal Genomic DNA Sequences
Science Daily ^ | 10-14-2007 | Public Library of Science

Posted on 10/15/2007 10:45:59 AM PDT by blam

Source: Public Library of Science
Date: October 14, 2007

Inconsistencies With Neanderthal Genomic DNA Sequences

Science Daily — Were Neanderthals direct ancestors of contemporary humans or an evolutionary side branch that eventually died out?

This is one of the enduring questions in human evolution as scientists explore the relationship of fossil groups, such as Neanderthals, with people alive today. Two recent papers describing the sequencing of Neanderthal nuclear DNA from fossil bone held promise for finally answering this question [1, 2].

However, the two studies came to very different conclusions regarding the ancestral role of Neanderthals. Jeffrey D. Wall and Sung K. Kim from University of California San Francisco now reveal in PLoS Genetics what they found when they reanalyzed the data from the two original studies.

Wall and Kim's reanalysis reveals inconsistencies between them and they believe that possible contamination with modern human DNA and/or a high rate of sequencing errors compromised the findings of one of the original Neanderthal DNA studies.

The authors therefore recommend that we carefully evaluate published and future data before arriving at any firm conclusions about human evolution.

References

1. Noonan JP, Coop G, Kudaravalli S, Smith D, Krause J, et al. (2006) Sequencing and analysis of Neanderthal genomic DNA. Science 314: 1113-1118.

2. Green RE, Krause J, Ptak SE, Briggs AW, Ronan MT, et al. (2006) Analysis of one million base pairs of Neanderthal DNA. Nature 16: 330-336.

Citation: Wall JD, Kim SK (2007) Inconsistencies in Neanderthal genomic DNA sequences. PLoS Genet 3(10): e175. doi:10.1371/journal.pgen.0030175


TOPICS: News/Current Events
KEYWORDS: dna; evolution; genomic; godsgravesglyphs; helixmakemineadouble; neandertal; neandertals; neanderthal; neanderthals; sequences
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1 posted on 10/15/2007 10:46:02 AM PDT by blam
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To: SunkenCiv

GGG Ping.


2 posted on 10/15/2007 10:46:31 AM PDT by blam (Secure the border and enforce the law)
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To: blam
But they still don't answer the history-changing, 10 quadrillion dollar question: how do species evolve?
3 posted on 10/15/2007 10:50:28 AM PDT by wastedyears (I don't wanna grow up, help : /)
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To: blam

Makes you kind of wonder about the accuracy of any gene sequencing....


4 posted on 10/15/2007 11:04:21 AM PDT by Adder (hialb)
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To: blam

Some interesting observations:

http://www.amazon.com/gp/product/0890512388/

Buried Alive: The Startling Truth About Neanderthal Man
by Jack Cuozzo


5 posted on 10/15/2007 11:05:57 AM PDT by Ozone34
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To: blam

Anyone who has met my ex mother-in-law would know that the Neanderthal species is still alive


6 posted on 10/15/2007 11:08:43 AM PDT by Old Seadog (Inside every old person is a young person saying "WTF happened?".)
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To: Adder

Or the results didn’t match what they wanted to find.


7 posted on 10/15/2007 11:08:49 AM PDT by Tut
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To: Adder
Makes you kind of wonder about the accuracy of any gene sequencing....

Not really. The older you go the more difficult it gets.

Living individuals are easy.

8 posted on 10/15/2007 11:13:51 AM PDT by Coyoteman (Religious belief does not constitute scientific evidence, nor does it convey scientific knowledge.)
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To: Old Seadog

lol


9 posted on 10/15/2007 11:15:40 AM PDT by martin_fierro (< |:)~)
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To: caryatid; CobaltBlue; Jessarah; Ol' Sox; Old Student; Pharmboy; RikaStrom; StayAt HomeMother

Partial-”I’m Missing My GGG Ping List Today” Ping


10 posted on 10/15/2007 11:17:31 AM PDT by martin_fierro (< |:)~)
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To: blam

What, no GEICO cavemen pictures??

That show is pretty funny BTW. I was surprised at how lowkey the humor is and very very dry wit. But some really funny references/jokes for thirty something’s.


11 posted on 10/15/2007 11:38:50 AM PDT by Southerngl
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To: Southerngl

Were Neanderthals direct ancestors of contemporary humans or an evolutionary side branch that eventually died out?

“What, no GEICO cavemen pictures??”

A picture of Harry Reid would convince me that Neaderthals still roam the globe


12 posted on 10/15/2007 11:43:37 AM PDT by AlphaOneAlpha
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and with a big smile...
The Neandertal Enigma
by James Shreeve
Frayer's own reading of the record reveals a number of overlooked traits that clearly and specifically link the Neandertals to the Cro-Magnons. One such trait is the shape of the opening of the nerve canal in the lower jaw, a spot where dentists often give a pain-blocking injection. In many Neandertal, the upper portion of the opening is covered by a broad bony ridge, a curious feature also carried by a significant number of Cro-Magnons. But none of the alleged 'ancestors of us all' fossils from Africa have it, and it is extremely rare in modern people outside Europe." [pp 126-127]

13 posted on 10/15/2007 12:23:46 PM PDT by SunkenCiv (Profile updated Friday, October 5, 2007. https://secure.freerepublic.com/donate/)
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To: Adder
Makes you kind of wonder about the accuracy of any gene sequencing....

Not really. I used to work in a DNA sequencing lab. You're not going to contaminate the sample unless you're pretty sloppy.
14 posted on 10/15/2007 12:26:46 PM PDT by mysterio
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To: blam; StayAt HomeMother; Ernest_at_the_Beach; 1ofmanyfree; 24Karet; 3AngelaD; 49th; ...

· join list or digest · view topics · view or post blog · bookmark · post a topic ·

 
Gods
Graves
Glyphs
Thanks Blam. Of course, the myth that a study was done showing Neandertal is an extinct cousin will persist.

To all -- please ping me to other topics which are appropriate for the GGG list.

The quarterly FReepathon is underway.
GGG managers are Blam, StayAt HomeMother, and Ernest_at_the_Beach
 

· Google · Archaeologica · ArchaeoBlog · Archaeology magazine · Biblical Archaeology Society ·
· Mirabilis · Texas AM Anthropology News · Yahoo Anthro & Archaeo ·
· History or Science & Nature Podcasts · Excerpt, or Link only? · cgk's list of ping lists ·


15 posted on 10/15/2007 12:27:20 PM PDT by SunkenCiv (Profile updated Friday, October 5, 2007. https://secure.freerepublic.com/donate/)
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To: SunkenCiv

So where do Adam and Eve come into things?


16 posted on 10/15/2007 12:31:11 PM PDT by Monkey Face (It's time for Halloween, so practice safe hex.)
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To: Old Seadog

Oh Yeah...I keep seeing vestigial neanderthals all the time too.

They are with us.


17 posted on 10/15/2007 1:42:47 PM PDT by eleni121 (+ En Touto Nika! By this sign conquer! + Constantine the Great)
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To: wastedyears
"how"? Through metaphysically induced dysplasia and hygeraphobia.

It's all intuitively obvious.

Now, sit down and be good. The Creos only claim the last 6500 years, if that, and all the rest of time is left to the Evos.

The Evos are working on the answer. The Creos are not concerned.

18 posted on 10/15/2007 2:28:34 PM PDT by muawiyah
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To: muawiyah

I’m only buzzed, but I have no idea what you’re talking about.

=D


19 posted on 10/15/2007 4:05:55 PM PDT by wastedyears (I don't wanna grow up, help : /)
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To: wastedyears
Give it some time. It'll come to you.

Chips? (holds out bag).

20 posted on 10/15/2007 4:46:37 PM PDT by muawiyah
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