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Keyword: inflammatorydisease

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  • How one inflammatory disorder exacerbates another

    04/29/2022 3:07:11 PM PDT · by ConservativeMind · 27 replies
    Medical Xpress / University of Pennsylvania / Cell / Nature Reviews Immunology ^ | Apr. 27, 2022 | Katherine Unger Baillie / Xiaofei Li et al / George Hajishengallis et al
    The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, perpetuating a misguided immune response. In a new paper, researchers demonstrated that recipients of a bone marrow transplant were predisposed to more severe arthritis if their donor had inflammatory gum disease. The researchers note that this mechanism may also prompt a reconsideration of how bone marrow donors are selected. …To put the whole picture together regarding the link between inflammatory conditions, the "critical experiment,"...