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An Oklahoma woman has filed a lawsuit against Arby’s and a former restaurant manager after alleging the employee intentionally spat into her food while experiencing an active oral herpes outbreak, resulting in the customer contracting the virus. The lawsuit, filed on June 16 in McCurtain County, centers on an incident that allegedly occurred in late March at an Arby’s restaurant in Broken Bow, Oklahoma. According to the civil complaint, Amanda Hendricks, 38, was the manager on duty when Jennica Church visited the drive-thru after finishing a late bartending shift. Church said the wait for her order seemed unusually long. “I...

Herpes simplex virus 1 has an internal pressure eight times higher than a car tire, and uses it to literally blast its DNA into human cells, according to a new study published online in the Journal of the American Chemical Society.Dr Alex Evilevitch and his colleagues provide the first experimental evidence of a high internal pressure of tens of atmospheres within Herpes simplex virus 1, resulting from the confined genome. NPC – nuclear pore complex (Bauer DW et al) The study provides the first experimental evidence of high internal pressure within a virus that infects humans – a phenomenon previously...

New compounds to fight the herpes simplex virus (HSV-1), which causes cold sores, have been made by researchers from Italy. The compounds' antiviral activity could be enhanced further by encapsulating them in a cyclodextrin nanocarrier that acts as a delivery system. Giovanni Grassi and colleagues from the University of Messina made indole-3,4-diones that share structural features with inhibitors of kinase - an enzyme linked to many diseases. The inhibitors were recently reported to prevent viral replication in vitro. 'The diones showed remarkable anti HSV-1 activity in vitro,' says Grassi. They then encapsulated the most effective dione in an amphiphilic - both hydrophilic and lipophilic - cyclodextrin....

Alzheimer's caused by cold sore virus? In a connection that sounds borderline preposterous, links have been accumulating between Alzheimer's disease and cold sores....Cold sores are caused by the herpes simplex virus type 1, a type that should not be confused with herpes symplex virus type 2 which is the cause of genital herpes. A growing body of research, suggests that the HSV-1 may also be responsible for the majority of Alzheimer's cases.... "There's clearly a very strong connection," says British researcher, Ruth Itzhaki, Ph.D., speaking one afternoon in her office at the University of Manchester, in northwestern England. A neurobiologist,...