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  • Drugs that mimic effects of cigarette smoke reduce SARS-CoV-2's ability to enter cells

    09/11/2021 2:15:29 PM PDT · by LesbianThespianGymnasticMidget · 95 replies
    Medical Xpress ^ | SEPTEMBER 10, 2021 | Hiroshima University
    Researchers have identified a potential reason why lower numbers of COVID cases have appeared amongst smokers compared to non-smokers, even as other reports suggest smoking increases severity of the disease. Researchers have identified two drugs that mimic the effect of chemicals in cigarette smoke to bind to a receptor in mammalian cells that inhibits production of ACE2 proteins, a process that appears to reduce the ability of the SARS-CoV-2 virus to enter the cell. The findings appear in the journal Scientific Reports on 17 August. Something of a paradox exists with respect to smoking cigarettes and COVID-19. Active smoking is...