The glymphatic system is the brain's self-cleaning mechanism. It wasn't discovered until 2012. The glymphatic system is tied to the circadian system and sleep architecture, and both are implicated in the pathophysiology of concussions. I'll explain the glymphatic system's nature, how its dysfunction contributes to concussion pathology, and the crucial role of circadian therapy in mitigating this impact. The glymphatic system was nicknamed "the garbage truck of the brain" by its discoverer. Its fundamental role is to remove waste products from the brain. Approximately 80–90% of glymphatic clearance occurs during "deep sleep." As sleep transitions from deep sleep into the...
