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Medications for type 2 diabetes and obesity known as GLP-1 receptor agonists may lower the risk of acute pancreatitis recurrence in people with obesity and those with type 2 diabetes, according to a study. Doctors have been cautious about prescribing these medications in patients with a history of pancreatitis due to the potential risk of worsening the condition, said Mahmoud Nassar, M.D., Ph.D. Acute pancreatitis is a sudden inflammation of the pancreas. The researchers used data from a database called TriNetX, which contains information from about 127 million patients across 15 countries, mainly from the United States. They identified 638,501...

"We find that there is a peptide hormone in the gut called GLP1 that increases the secretion of insulin only when the blood glucose is high. This effectively eliminates the risk of hypoglycemic shock. Another advantage is that GLP1 administration has been found to stimulate weight-loss. The hormone offers the promise of revolutionising the treatment of Type II diabetes and reduce obesity," he said.