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Immunotherapy has been shown to greatly improve survival rates for certain types of cancer. However, in some cases, it can lead to an over-activation of the immune system, which can be dangerous. In a recent review by researchers, potential therapies have been identified, which might make it possible to continue with immunotherapy even when facing severe side effects. For certain types of cancer, immunotherapy has greatly improved survival rates. However, in some patients, it can lead to a dangerous over-activation of the immune system. This rare side effect was only clinically recognized during regular clinical use rather than in clinical...

Controversies surrounding hormone therapy (HT) and its benefits and risks have dominated the women's health field for more than 2 decades. A large new study demonstrates that, despite some commonly held misperceptions, HT doesn't increase a woman's risk of developing lung cancer, and it could actually help reduce the risk. Lung cancer remains one of the most common malignancies and the leading cause of cancer mortality worldwide. After breast cancer, it is the most common cancer in women, with its incidence increasing in women over the past few decades. Although smoking remains the number-one risk factor for developing lung cancer,...

Patients with resectable non–small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes, according to results. Forde, Rosner, and colleagues previously reported safety and efficacy results from a phase II clinical trial in which patients with stage I-III resectable NSCLC were treated with two doses of neoadjuvant nivolumab. Major pathological responses were observed in 45% of patients, independent of tumor PD-L1 expression, and 73% of patients whose tumors were surgically resected were recurrence-free 18 months following surgery. The latest publication reports the final analyses from this trial,...