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Keyword: cvd

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  • Combo therapy cuts risk of heart attacks and strokes in half

    08/30/2021 6:14:58 PM PDT · by george76 · 30 replies
    Medical Xpress ^ | AUGUST 29, 2021 | McMaster University
    A combination therapy of aspirin, statins and at least two blood pressure medications given in fixed doses can slash the risk of fatal cardiovascular disease (CVD) by more than half, says an international study led by Hamilton researchers. The fixed-dose combination (FDC) therapies were examined both with and without aspirin versus control groups in a combined analysis of more than 18,000 patients without prior CVD from three large clinical trials. FDCs including aspirin cut the risk of heart attacks by 53 percent, stroke by 51 percent, and deaths from cardiovascular causes by 49 percent. The results were welcomed by international...
  • Reducing Cholesterol Yields Inconsistent Benefits Despite Guidelines

    08/14/2020 11:10:10 AM PDT · by Pining_4_TX · 40 replies
    American Council on Science and Health ^ | 08/05/20 | Chuck Dinerstein
    “Between 2002 and 2013 statin use in the US nearly doubled, cholesterol levels are falling, yet cardiovascular deaths appear to be on the rise.”
  • CPAP provides relief from depression

    07/05/2019 1:48:23 PM PDT · by ConservativeMind · 23 replies
    Medical XPress ^ | July 1, 2019 | Flinders University
    Researchers have found that continuous positive airway pressure (CPAP) treatment of obstructive sleep apnea (OSA) can improve depression symptoms in patients suffering from cardiovascular diseases. Using data from the Sleep Apnea Cardiovascular Endpoints (SAVE) trial led by Flinders University, the new study has found a significant decrease in cases of depression after patients received CPAP treatment for their sleep apnea. This is by far the largest trial of its type and one of very few studies reporting such an effect, says Professor Doug McEvoy from Flinders University. From detailed analysis of the SAVE data, Flinders University experts and collaborators at...
  • A New Reason Why Red Meat, and Some Energy Drinks, May Be Bad for Our Heart

    04/09/2013 2:35:06 PM PDT · by neverdem · 59 replies
    ScienceNOW ^ | 7 April 2013 | Jennifer Couzin-Frankel
    Our guts are awash in bacteria, and now a new study fingers them as culprits in heart disease. A complicated dance between the microbes and a component of red meat could help explain how the food might cause atherosclerosis. The work also has implications for certain energy drinks and energy supplements, which contain the same nutrient that these bacteria like chasing after. Red meat is considered bad news when it comes to heart health, although studies aren't consistent about how much can hurt and whether it always does. Furthermore, it's not clear which components of meat are doing harm. Various...
  • Scientists Spot How Cox-2 Painkillers Raise Heart Risks

    05/07/2012 4:08:49 AM PDT · by neverdem · 27 replies ^ | May 2, 2012 | NA
    New research has uncovered how some cox-2 painkillers increase the risk for both heart attacks and stroke. The once popular cox-2 drugs, Vioxx and Bextra, were pulled off the market in 2004 and 2005, respectively, after research showed that both raised the chances of cardiovascular trouble. Meanwhile, Celebrex, a painkiller in the same drug class that remains on the market, carries a "black box" warning alerting patients to potential heart risks. Now, a team of scientists from the University of Pennsylvania in Philadelphia say that, although cox-2 inhibitors are very good at inhibiting the workings of the cox-2 enzyme --...
  • The Washington Diet - Following the government’s nutritional advice can make you fat and sick.

    05/25/2011 7:15:33 PM PDT · by neverdem · 13 replies
    City Journal ^ | Spring 2011 | Steven Malanga
    Last October, embarrassing e-mails leaked from New York City’s Department of Health and Mental Hygiene disclosed that officials had stretched the limits of credible science in approving a 2009 antiobesity ad, which depicted a stream of soda pop transforming into human fat as it left the bottle. “The idea of a sugary drink becoming fat is absurd,” a scientific advisor warned the department in one of the e-mails, a view echoed by other experts whom the city consulted. Nevertheless, Gotham’s health commissioner, Thomas Farley, saw the ad as an effective way to scare people into losing weight, whatever its scientific...
  • Researchers find link between common dietary fat, intestinal microbes and heart disease

    04/08/2011 1:19:41 PM PDT · by decimon · 48 replies
    Lerner Research Institute ^ | April 6, 2011 | Unknown
    How specific digestive tract microbes react to a dietary lipid increases risk of heart attack, stroke and deathA new pathway has been discovered that links a common dietary lipid and intestinal microflora with an increased risk of heart disease, according to a Cleveland Clinic study published in the latest issue of Nature. The study shows that people who eat a diet containing a common nutrient found in animal products (such as eggs, liver and other meats, cheese and other diary products, fish, shellfish) are not predisposed to cardiovascular disease solely on their genetic make-up, but rather, how the micro-organisms that...
  • Atherosclerotic plaques formed during a late and limited time period in life

    04/08/2011 1:10:22 PM PDT · by decimon · 8 replies
    Karolinska Institutet ^ | April 8, 2011 | Katarina Sternudd
    In a new study performed in humans, researchers from Karolinska Institutet have determined the age of atherosclerotic plaques by taking advantage of Carbon-14 (14C) residues in the atmosphere, prevailing after the extensive atomic bomb tests in the 50ties and 60ties. The findings, published in the scientific online journal PLoS ONE, suggest that in most people plaque formation occurs during a relatively short and late time period in life of 3-5 years. > "We suspected that the plaque would be substantially younger than the patients, who were on average were 68 years old at surgery, but we were surprised when we...
  • The Cholesterol Myths: Exposing the Fallacy that Saturated Fat and Cholesterol Cause Heart Disease

    10/30/2001 9:25:13 AM PST · by sourcery · 45 replies · 13,962+ views ^ | Review: [Joel M. Kauffman, Research Professor Chemistry]; Book: [Uffe Ravnskov, M. D., Ph. D.]
    <p>With courage and care Dr. Ravnskov exposes the lack of experimental evidence for the diet-heart theory, which claims that eating less fat and cholesterol will prevent atheroslcerosis (hardening of the arteries) and myocardial infarctions (heart attacks). By examining original peer-reviewed literature, the author finds no support for the diet-heart theory. He gives examples of scientific fraud among efforts to support the theory, including the deliberate selective omission of data points, and the deliberate assignment of subjects in a clinical trial to treatment or to control groups by physicians with the subject's medical records in hand. He shows how the abstract or conclusions of a number of papers are at odds with the actual data in the papers. He demonstrates how the use of one statistical method in preference to another can give a false impression that there is an effect, where there is, in fact, none. He shows how the reporting of differences in fatality rates by per cent reduction (say, a 50% reduction in relative risk) is actually misleading when the actual death rates are quite small in both the treatment and control groups of subjects in diet or drug studies. For example, a treatment that changes the absolute survival rate over a multi-year period from 99.0% to 99.5% represents a 50% reduction in relative risk, from 1% to 0.5% absolute. This is often described in papers as a 50% reduction in death rate. However, when the difference is barely significant statistically, as was often the case, Ravnskov points out that there is no real reason to recommend adoption of the treatment, especially if there are serious side-effects.</p>
  • Meta-analysis evaluating the association of saturated fat with cardiovascular disease

    01/25/2010 10:04:28 PM PST · by Coleus · 27 replies · 969+ views
    American Society for Clinical Nutrition ^ | January 13, 2010 | Patty W Siri-Tarino, Qi Sun, Frank B Hu and Ronald M Krauss
    Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease1,2,3,4,5Patty W Siri-Tarino, Qi Sun, Frank B Hu and Ronald M Krauss1 From the Children's Hospital Oakland Research Institute Oakland CA (PWS-TRMK)the Departments of Nutrition (QSFBH)Epidemiology (FBH) Harvard School of Public Health Boston MA. 2 PWS-T and QS contributed equally to this work. 3 The contents of this article are solely the responsibility of the authors and do not necessarily represent the official view of the National Center for Research Resources ( or the National Institutes of Health. 4 Supported by the National Dairy Council (PWS-T and...
  • Nanotubes to soak up oil spills

    11/13/2009 10:03:13 PM PST · by neverdem · 5 replies · 531+ views
    Chemistry World ^ | 11 November 2009 | Lewis Brindley
    Chinese chemists have made sturdy nanotube sponges that can selectively absorb oil and volatile chemicals in preference to water. The sponges float on water and can absorb up almost 180 times their own weight in oil, giving them great potential for mopping up industrial spillages. 'We are very excited about the potential of our material,' says Anyuan Cao, who led the work at Peking University, Beijing, China. 'The sponges can absorb a variety of oils - from volatile solvents to thick and sticky oil - but they are also elastic and robust. They can be wrung out like towels and re-used,...
  • BUSM researchers propose a relationship between androgen deficiency and cardiovascular disease

    09/25/2009 12:41:59 PM PDT · by decimon · 4 replies · 345+ views
    Boston University Medical Center ^ | Sep 25, 2009 | Unknown
    (Boston) - Researchers from Boston University School of Medicine (BUSM) in collaboration with researchers from Lahey Clinic Northshore, Peabody, Mass., believe that androgen deficiency might be the underlying cause for a variety of common clinical conditions, including diabetes, erectile dysfunction, metabolic syndrome and cardiovascular disease (CVD). These findings appear in the September/October issue of the Journal of Andrology. Androgens are a steroid hormone, such as testosterone, that controls the development and maintenance of male characteristics. In a number of studies, androgen deficiency has been linked to an increased mortality in men. Testosterone (T) is an anabolic hormone with a wide...
  • Cardiovascular disease gets personal

    08/22/2009 12:03:18 AM PDT · by neverdem · 14 replies · 655+ views
    Nature News ^ | 19 August 2009 | Erika Check Hayden
    Gene-association studies hint at better ways of treating the leading cause of death, but capitalizing on them is proving to be a slow and difficult process. Erika Check Hayden reports. Cardiovascular conditions are the leading cause of death worldwide.A. MASSEE/SPL As personalized cancer treatment edges into the clinic, doctors and scientists are hoping that cardiovascular disease — the world's top killer — will be next to benefit from genomics.An avalanche of studies has linked genetic variants to various cardiovascular conditions and to patients' responses to commonly prescribed drugs. First up could be genetic guidance for the anti-clotting agents warfarin and...
  • RA, Others Join Diabetes as Major CVD Risk Factors: Consensus on management reached.

    07/21/2009 1:02:32 AM PDT · by neverdem · 8 replies · 456+ views
    Family Practice News ^ | 1 July 2009 | MITCHEL L. ZOLER
    COPENHAGEN — Rheumatoid arthritis and two other rheumatic diseases are as strong as diabetes as risk factors for cardiovascular disease, prompting a European League Against Rheumatism task force to issue the group's first consensus recommendations for managing cardiovascular risk in patients with rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. “In our view, rheumatoid arthritis [RA], ankylosing spondylitis [AS], and psoriatic arthritis [PsA] should be seen as new, independent cardiovascular risk factors,” Dr. Michael T. Nurmohamed said at the annual European Congress of Rheumatology. “Very importantly, the risk is comparable to type 2 diabetes,” added Dr. Nurmohamed, a rheumatologist at the...
  • Huge study boosts disappointment on multivitamins

    02/09/2009 5:53:28 PM PST · by neverdem · 16 replies · 961+ views
    San Luis Obispo Tribune ^ | Feb. 09, 2009 | LINDSEY TANNER
    AP Medical Writer The largest study ever of multivitamin use in older women found the pills did nothing to prevent common cancers or heart disease. The eight-year study in 161,808 postmenopausal women echoes recent disappointing vitamin studies in men. Millions of Americans spend billions of dollars on vitamins to boost their health. Research has focused on cancer and heart disease in particular because of evidence that diets full of vitamin-rich foods may protect against those illnesses. But that evidence doesn't necessarily mean pills are a good substitute...
  • Study: Stem Cells Used To Fix Your Broken Heart

    07/01/2008 6:59:11 PM PDT · by Coleus · 3 replies · 244+ views
    cbs ^ | 06.30.08
    Study: Stem Cells Used To Fix Your Broken Heart It's Called The Marvel Study The Largest Clinical Trial Investigating Adult Stem Cells To Treat Congestive Heart Failure For More Info, Call Jim Moran Heart & Vascular Center At (954) 229-8400 MIAMI (CBS4) ― Doctors are discovering a new way to fix your broken heart. A study is underway in South Florida that could revolutionize the way heart attack patients help their damaged hearts by using their own stem cells. It's called The Marvel Study and under the direction of Dr. Alan Neiderman with the Jim Moran Heart & Vascular Research...
  • Stem cells – hope or hype? Adult Stem Cells from leg used to treat heart disease

    06/27/2008 8:33:23 PM PDT · by Coleus · 2 replies · 170+ views
    After 21 years of unsuccessful heart treatments, including several heart procedures, 68-year-old Coenie de Jongh was desperate. So when his cardiologist suggested a last-resort experimental therapy, it represented a literal life line.  Coenie, from Bloubergstrand near Cape Town, had his first heart attack at the young age of 40. A bypass operation followed and his condition improved, but seven years later Coenie’s health started deteriorating again. More operations and more intense treatment followed, but in 2002 his health took a real turn for the worse.  His condition was so bad he struggled to find a cardiologist who was willing to...
  • Participants in lower limb ischemia Experiencing Remarkable Results (Adult Stem Cells)

    06/28/2008 8:26:38 PM PDT · by Coleus · 3 replies · 251+ views
    pharmalive ^ | 05,29.08
    Participants in a Federal Drug Administration (FDA) protocol at TCA Cellular Therapy utilizing stem cells to treat lower limb ischemia are experiencing increased mobility and decreased pain in lower legs. Lower limb ischemia is a condition where plaque build-up causes decreased circulation in the lower leg. Symptoms of the condition include intense pain and swelling. Study participants may have had different factors that contributed to their condition: a family history of Peripheral Artery Disease (PAD), history of smoking and other vascular conditions. Common among them however, were that more traditional treatments (utilizing stents and grafts) were ineffectual and that the...
  • Adult stem cells to repair hearts damaged by severe coronary artery disease investigated

    03/03/2007 6:26:36 PM PST · by Coleus · 159+ views
    EurekAlert ^ | 02.01.07 | Mary Ann Schultz
    Trial involves injecting patients' own (autologous) stem cells into areas of their hearts with poor blood flow CHICAGO - Rush University Medical Center is one of the first medical centers in the country, and currently the only site in Illinois, participating in a novel clinical trial to determine if a subject’s own stem cells can treat a form of severe coronary artery disease. The Autologous Cellular Therapy CD34-Chronic Myocardial Ischemia (ACT34-CMI) Trial is the first human, Phase II adult stem cell therapy study in the U.S. designed to investigate the efficacy, tolerability, and safety of blood-derived selected CD34+ stem cells...
  • Could a dose of vitamin B save you from a heart attack?

    03/04/2007 6:07:28 PM PST · by Coleus · 19 replies · 1,125+ views
    Daily Mail ^ | 12.05.06 | JEROME BURNE
    Amino acids: Key to a healthier heart? Could taking a few B vitamins cut your risk of a heart attack or a stroke? That's the suggestion from a study published last week in the British Medical Journal (BMJ).  The key is an amino acid called homocysteine, a substance made when the protein we eat is digested — already there is growing evidence to link it with cardiovascular disease, and even stroke. Homocysteine — with the help of the B vitamins including B12 and folate — is rapidly turned into other useful compounds such as the amino acids cysteine and...