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  • Small Molecule Compound Developed That Can Degrade the Cancer Promoting Protein SUMO1

    10/14/2021 5:36:37 PM PDT · by nickcarraway
    Medical Xpress ^ | OCTOBER 14, 2021 | Bob Yirka
    A team of researchers working at the Indiana University School of Medicine, has developed a compound that can degrade the cancer-promoting protein SUMO1. In their paper published in the journal Science Translational Medicine, the group describes their work in attempting to find a degrader for what has been described as an undruggable cancer-related protein. Prior research has shown that there are some proteins that change cancer proteins in ways that help it form and spread, but which are considered to be undruggable, meaning that it appears unlikely that a drug could be developed that would prevent it from doing its...