Bison are one of over 100 species of hoofed mammals belonging to the Bovidae family, which also includes cattle. While often grouped with buffalo, their anatomical features slightly differ. Historically, bison has been the second most popular type of red meat, with beef being number one. Today, the demand for bison meat is growing due to increased marketing efforts, its widespread availability, and favorable nutritional profile. This article reviews bison’s nutritional profile, benefits, and drawbacks and compares it with beef. Nutrition In terms of nutrient content, bison packs a good amount of several essential nutrients, including protein, iron, zinc, selenium,...