A medication for heart problems and high blood pressure may also be effective for treating alcohol use disorder. The study presents converging evidence from experiments in mice and rats, as well as a cohort study in humans, suggesting that the medication, spironolactone, may play a role in reducing alcohol drinking. Currently there are three medications approved for alcohol use disorder in the United States. Given the diverse biological processes that contribute to alcohol use disorder, new medications are needed to provide a broader spectrum of treatment options. Previous research has shown that mineralocorticoid receptors, which are located throughout the brain...
