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Alzheimer's Association Supplemental thiamine [vitamin B-1] as a practical, potential way to prevent Alzheimer's disease from commencingFirst published: 28 July 2021 Author: Jeffrey Fessel “… In brief: it is easier to prevent Alzheimer's than to try to reverse it after it has developed. The data supporting the prophylactic use of thiamine are robust. In order to validate its use, a clinical trial is advocated that would enroll persons aged 65 or older who have evidence of depositions of amyloid or tau in their brains, and randomly assign them to take, for as long as 5 years, either thiamine 100 mgs...

GALVESTON, Texas — University of Texas Medical Branch at Galveston researchers have discovered that a form of vitamin B1 could become a new and effective treatment for one of the world's leading causes of blindness. Scientists believe that uveitis, an inflammation of the tissue located just below the outer surface of the eyeball, produces 10 to 15 percent of all cases of blindness in the United States, and causes even higher rates of blindness globally. The inflammation is normally treated with antibiotics or steroid eye drops. In a paper appearing in the May issue of the journal Investigative Ophthalmology and...

Vitamin supplement little more than 'snake oil'June 12,2008 A popular vitamin supplement is being advertised with claims that are demonstrably untrue, as revealed by research published in the open access journal BMC Pharmacology. Benfotiamine is a synthetic derivative of thiamine (vitamin B1). It is marketed heavily as a dietary supplement using a selection of unsubstantiated, 'not-quite-medical' claims that tend to characterize this field. A large part of this campaign has been built around the belief that benfotiamine is lipid-soluble and, therefore, more physiologically active. Scientific research led by Dr Lucien Bettendorff of the Center for Cellular and Molecular Neurobiology at...

Diabetes damage linked to vitamin B1 shortage Last Updated: 1:43am BST 08/08/2007 Diabetics have three-quarters less vitamin B1 in their blood than healthy people, research has shown. A study by the University of Warwick has linked this shortfall, which occurs in sufferers with both type one and two of the disease, to damage to the kidneys, retina and nerves in the arms and legs that are all common symptoms of the disease. Prof Paul Thornalley, from the university, said that vitamin supplements could be taken by all diabetics and would work alongside conventional glucose controls. The study is published in...