Critical elements of one of the most cited pieces of Alzheimer’s disease research in the last two decades may have been purposely manipulated, according to a report in Science. **SNIP** The highly influential paper, which was published in Nature in 2006, has helped guide billions of dollars in US federal government research into Alzheimer’s, according to Science. The study, which looked at cognitive decline in mice, proposed that a specific amyloid protein may be responsible for cognitive decline. The hypothesis has since dominated the field, and researchers have worked for years to understand the mechanism by which such proteins may...