Free Republic
Browse · Search
News/Activism
Topics · Post Article

Skip to comments.

New Clues to Sex Anomalies in How Y Chromosomes Are Copied
NY Times ^ | September 15, 2009 | NICHOLAS WADE

Posted on 09/15/2009 11:00:27 PM PDT by neverdem

The first words ever spoken, so fable holds, were a palindrome and an introduction: “Madam, I’m Adam.”

A few years ago palindromes — phrases that read the same backward as forward — turned out to be an essential protective feature of Adam’s Y, the male-determining chromosome that all living men have inherited from a single individual who lived some 60,000 years ago. Each man carries a Y from his father and an X chromosome from his mother. Women have two X chromosomes, one from each parent.

The new twist in the story is the discovery that the palindrome system has a simple weakness, one that explains a wide range of sex anomalies from feminization to sex reversal similar to Turner’s syndrome, the condition of women who carry only one X chromosome.

The palindromes were discovered in 2003 when the Y chromosome’s sequence of bases, represented by the familiar letters G, C, T and A, was first worked out by David C. Page of the Whitehead Institute in Cambridge, Mass., and colleagues at the DNA sequencing center at Washington University School of Medicine in St. Louis.

They came as a total surprise but one that immediately explained a serious evolutionary puzzle, that of how the genes on the Y chromosome are protected from crippling mutations.

Unlike the other chromosomes, which can repair one another because they come in pairs, one from each parent, the Y has no evident backup system. Nature has prevented it from recombining with its partner, the X, except at its very tips, lest its male-determining gene should sneak into the X and cause genetic chaos.

Discovery of the palindromes explained how the Y chromosome has managed over evolutionary time to discard bad genes: it recombines with itself. Its essential genes are embedded in a series of eight...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: dna; genetics; godsgravesglyphs; science; sexanomalies; ychromosome
Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes
1 posted on 09/15/2009 11:00:28 PM PDT by neverdem
[ Post Reply | Private Reply | View Replies]

To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
Patient with ulcer collapses and dies after paramedics tell her: 'Stop being a drama queen' -UK

How manuka honey helps fight infection

Piece from childhood virus may save soldiers' lives

How stem cells make skin

FReepmail me if you want on or off my health and science ping list.

2 posted on 09/15/2009 11:23:32 PM PDT by neverdem (Xin loi minh oi)
[ Post Reply | Private Reply | To 1 | View Replies]

To: neverdem

Like a certain hermaphrodite world leader?


3 posted on 09/15/2009 11:24:54 PM PDT by null and void (We are now in day 237 of our national holiday from reality. - 0bama really isn't one of US.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: neverdem

So to cool neverd

Fascinating would be an understatement. The part about the mutual pair repair quality seems a bridge to far, let alone a special case lacking the feature… New vista.

Tanks for the pop. Rab


4 posted on 09/15/2009 11:42:14 PM PDT by Rabin
[ Post Reply | Private Reply | To 1 | View Replies]

To: null and void

“Like a certain hermaphrodite world leader?”

Whom? Thanks in advance.


5 posted on 09/15/2009 11:58:04 PM PDT by awaken2spirit (When one fornicates with ignorance, the result of that union is chaos.)
[ Post Reply | Private Reply | To 3 | View Replies]

To: neverdem

When the Y chromosome is damaged, you get a Democrat.


6 posted on 09/16/2009 12:18:11 AM PDT by OrangeHoof (YES WE CAN have a Depression.)
[ Post Reply | Private Reply | To 2 | View Replies]

To: neverdem

“Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes”

Well - there goes the mood I had when I first saw “sex anomalies” in the title!


7 posted on 09/16/2009 12:29:21 AM PDT by 21twelve (Drive Reality out with a pitchfork if you want , it always comes back.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: neverdem
The new twist in the story is the discovery that the palindrome system has a simple weakness, one that explains a wide range of sex anomalies from feminization to sex reversal similar to Turner’s syndrome, the condition of women who carry only one X chromosome.

Turner syndrome(XO), poly-x syndrome(XXX), Jacob syndrome(XYY) and Klinefelter syndrome (XXY)

8 posted on 09/16/2009 1:21:51 AM PDT by Sir Francis Dashwood (Arjuna, why have you have dropped your bow???)
[ Post Reply | Private Reply | To 1 | View Replies]

To: OrangeHoof
When the Y chromosome is damaged, you get a Democrat.

And this explains Nancy Pelosi how?

ML/NJ

9 posted on 09/16/2009 4:45:11 AM PDT by ml/nj
[ Post Reply | Private Reply | To 6 | View Replies]

To: awaken2spirit

The ‘One’ is all sexes, all beliefs, and all personal redemptions.


10 posted on 09/16/2009 5:24:53 AM PDT by allmost
[ Post Reply | Private Reply | To 5 | View Replies]

To: awaken2spirit

Akhenaten.


11 posted on 09/16/2009 7:36:25 AM PDT by null and void (We are now in day 237 of our national holiday from reality. - 0bama really isn't one of US.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: allmost
Hey, would you release your birth certificate if it said you were born undecided?

Voting "present" from day one?

12 posted on 09/16/2009 7:38:35 AM PDT by null and void (We are now in day 237 of our national holiday from reality. - 0bama really isn't one of US.)
[ Post Reply | Private Reply | To 10 | View Replies]

To: Rabin

This is a cool discovery. Ain’t this stuff fascinating?


13 posted on 09/16/2009 9:40:28 AM PDT by AFPhys ((Praying for our troops, our citizens, that the Bible and Freedom become basis of the US law again))
[ Post Reply | Private Reply | To 4 | View Replies]

To: neverdem; StayAt HomeMother; Ernest_at_the_Beach; 1ofmanyfree; 21twelve; 24Karet; 2ndDivisionVet; ..

· join list or digest · view topics · view or post blog · bookmark · post a topic · subscribe ·

 
Gods
Graves
Glyphs
Hey, if there aren't some anomalies, ya just ain't doin' it right.

Thanks neverdem.

To all -- please ping me to other topics which are appropriate for the GGG list.
GGG managers are SunkenCiv, StayAt HomeMother, and Ernest_at_the_Beach
 

·Dogpile · Archaeologica · ArchaeoBlog · Archaeology · Biblical Archaeology Society ·
· Discover · Nat Geographic · Texas AM Anthro News · Yahoo Anthro & Archaeo · Google ·
· The Archaeology Channel · Excerpt, or Link only? · cgk's list of ping lists ·


14 posted on 09/16/2009 6:20:52 PM PDT by SunkenCiv (https://secure.freerepublic.com/donate/__Since Jan 3, 2004__Profile updated Monday, January 12, 2009)
[ Post Reply | Private Reply | To 1 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
News/Activism
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson