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Monoclonal antibody can change Covid scenario: Gangaram Hospital
The Pioneer ^ | IANS

Posted on 06/09/2021 9:18:07 AM PDT by Jyotishi

New Delhi -- At a time when the country is passing through the second wave of Covid-19, Delhi-based Sir Gangaram Hospital claims that monoclonal antibody can be a game changer with its better hold on the deadly pandemic.

As per the hospital, the monoclonal antibodies will change the scenario of Covid-19 pandemic very soon.

The healthcare facility came with new findings after treatment of two patients recently at its centre by successfully using monoclonal antibody which showed fast progression of symptoms within first seven days and changed the outcome.

A 36-year-old healthcare worker with high grade fever, cough, myalgia, severe weakness and leucopenia was administered REGCov2 (CASIRIVIMAB Plus IMDEVIMAB) on day six of disease, the hospital said in a statement.

"Patient's parameter improved within 12 hours and was discharged," said the hospital.

The second case was of R.K. Razdan, an 80-year-old male diabetic and hypertensive patient, who was presented with high grade fever, cough and toxic look.

Razdan's oxygen saturation was more than 95 per cent on room air. "CT Scan confirmed mild disease. He was given REGCov2 on Day 5 of disease. Patient's parameter improved with next 12 hours."

According to Pooja Khosla, Senior Consultant, Department of Medicine, Sir Ganga Ram Hospital, "Monoclonal antibody could prove to be a game changer in times to come if used at appropriate time."

"It can avoid hospitalization in high-risk group and progression to severe disease. It can help escaping or reducing the usage of steroids and immunomodulation which would further reduce the risk of fatal infections like Mucormycosis, secondary bacterial and viral infections like CMV."

Khosla said this awareness about early identification of high-risk category in our population and timely therapy with monoclonal antibody as day care treatment may reduce the burden of cost on healthcare sector.


TOPICS: Culture/Society; Foreign Affairs; News/Current Events
KEYWORDS: anthonyfauci; antibody; bacteria; casirivimab; coronavirus; covid; covid19; covidstooges; diabetes; disease; fever; health; hospital; hypertension; imdevimab; india; infection; leucopenia; medical; medicine; monoclonal; monoclonalantibodies; monoclonalantibody; mucormycosis; pain; regcov2; steroid; therapy; toxc; treatment; virus
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1 posted on 06/09/2021 9:18:07 AM PDT by Jyotishi
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To: Jyotishi

It was a game changer for my pts. Thank you President Trump


2 posted on 06/09/2021 9:23:06 AM PDT by arkfreepdom
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To: Jyotishi

There are many different varieties of monoclonal antibodies. They - like the vaccines - are EUA.

I had Bamlanivimab infused in March. Pain level went from a 7 to a 3 in hours.

It’s still experimental. They took Bamlanivimab off the market already.


3 posted on 06/09/2021 9:26:03 AM PDT by Responsibility2nd (I love my country. It’s my government that I hate.)
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To: Jyotishi
Gangaram Hospital Style
4 posted on 06/09/2021 9:27:43 AM PDT by Berlin_Freeper
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To: arkfreepdom

Both the Regeneron and Eli Lilly MABs have been written about as game-changers for maybe nine months now and STILL there is no widespread press coverage.

What’s the view in the medical profession? Are MABs widely prescribed for early- and mid-stage COVID? Are they widely known as effective treatment?

What do you think of the news that half-dose Regeneron MAB can be administered via injection and not require infusion?


5 posted on 06/09/2021 9:29:17 AM PDT by ProtectOurFreedom ("Pour les vaincre il faut de l'audace, encore de l'audace, toujours de l'audace")
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To: ProtectOurFreedom

Both the Regeneron and Eli Lilly MABs have been written about as game-changers for maybe nine months now and STILL there is no widespread press coverage.

_________________________________________________

Big Gov and Big Pharma don’t wants us sheeple knowing about the effectiveness of the infusions. They certainly don’t want us to knock out Covid with tried and true trusted meds like HCQ and Ivermectin.

No way. They want to push push PUSH non FDA vaccines on us. Use us like the Nazis used the Jews for medical experimentations.


6 posted on 06/09/2021 9:36:44 AM PDT by Responsibility2nd (I love my country. It’s my government that I hate.)
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To: Responsibility2nd
You wrote They took Bamlanivimab off the market already.

That is only partially true (if I may be allowed to do some "fact-checking"). Here is the FDA revocation dated 16 April 2021:

In response to a request from Eli Lilly and Company, the U.S. Food and Drug Administration (FDA) has revoked the Emergency Use Authorization (EUA) of bamlanivimab alone for the treatment of mild to moderate coronavirus disease 2019 (COVID-19) (EUA 90). Lilly made this request because there is now adequate supply of etesevimab for administration with bamlanivimab, and the combination neutralizes more of the emerging COVID-19 variants in the U.S. than bamlanivimab alone.

As a result, bamlanivimab alone is no longer authorized for use in the U.S., given the availability of authorized monoclonal antibody combinations. Importantly, revocation of the bamlanivimab alone (EUA 90) is not due to any new safety concerns.

Here is the replacement EUA for combined injection of bamlanivimab 700 mg/20 mL and etesevimab 700 mg / 20 mL.

I'm glad it worked so well for you!

7 posted on 06/09/2021 9:37:43 AM PDT by ProtectOurFreedom ("Pour les vaincre il faut de l'audace, encore de l'audace, toujours de l'audace")
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To: Responsibility2nd

It’s almost as if the pharma companies captured the regulator. But, no, that couldn’t happen.


8 posted on 06/09/2021 9:40:06 AM PDT by ProtectOurFreedom ("Pour les vaincre il faut de l'audace, encore de l'audace, toujours de l'audace")
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To: arkfreepdom

A game changer in our patients too. This is the state of the treatment art. Need to stop with the weakly effective ivermectin theories and get patients to the monoclonals.


9 posted on 06/09/2021 9:43:40 AM PDT by gas_dr (Conditions of Socratic debate: Intelligence, Candor, and Good Will. )
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To: ProtectOurFreedom

You are correct. Bonus points for you for being so thorough!

They did just that. Combined two into one.

And when my infusion was over, they gave me written instruction to NOT be vaccinated until 90 days had passed.

But knowing what we know now - I’ll never get a vaccine. Don’t need one. I’ve now got natural and chemically created antibodies.

Does that mean I’ll not get Covid again? No. I might.

But I’ll certainly not be putting myself at risk of those EUA vaccines.


10 posted on 06/09/2021 9:45:04 AM PDT by Responsibility2nd (I love my country. It’s my government that I hate.)
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To: Jyotishi

It seems to me that a large percent of medical doctors in the USA today are from India. Thus, I would respect the opinions of these medical doctors still in India more than many of the homegrown doctors in the USA.


11 posted on 06/09/2021 9:45:38 AM PDT by Presbyterian Reporter
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To: Responsibility2nd

You would sentence people to death by withholding actual efficacious treatment? Ivermectin and HCQ are not cures and at best weak treatments. They are not targeted to the pathogen like these meds are. If you don’t like vaccines these are the therapeutics that would threaten the EUA although I suspect the fda will fully approve vaccines in the next several months.


12 posted on 06/09/2021 9:46:02 AM PDT by gas_dr (Conditions of Socratic debate: Intelligence, Candor, and Good Will. )
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To: gas_dr

Good afternoon,

“Monoclonal antibody can change Covid scenario.”

If I understand correctly, this therapy would be used when patients are in either in-patient settings. Perhaps would expand to outpatient for further use?

From your vantage point of working with patients who have succumbed to the virus to the degree that they are in some sort of hospital setting, perhaps ivermectin is not the treatment of choice.*

That said, as a preventative combined with Vit D3, C, B, and Zinc Quercetin, melatonin, there seem to be evidence it has success. From some of the publications I have seen posted here, areas in India that use it are seeing positive results. Not sure about the country as a whole—rather large population.

*In Elmhurst IL, a family sued the hospital to allow a family member who had been on a vent and in a coma to be treated with Ivermectin.
https://www.webmd.com/lung/news/20210506/covid-patient-in-coma-gets-ivermectin-after-court-order

And she is improving:

https://kevinbae.com/2021/update-nurije-fype-slowly-improving-after-court-ordered-illinois-hospital-to-administer-ivermectin/

Seems to me the more tools we have in the toolbox, the better.


13 posted on 06/09/2021 10:10:45 AM PDT by Freedom56v2 (If I wanted to live in China, I would move there!)
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To: Jyotishi

It took a year to approve and release the mRNA vaccines. It took only a few weeks to release Remdesivir monoclonal antibody vaccine. If the United States had committed to mass-producing Remdesivir before it was approved then it could have stopped the COVID-19 epidemic in its tracks. mRNA long-term immunity could follow months later.


14 posted on 06/09/2021 10:17:37 AM PDT by nagant
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To: ProtectOurFreedom

They are given as outpatient infusion and we set up an area in covid er to give. It’s not 100 % but I haven’t had any require admission and some much to dramatic improvement after receiving.


15 posted on 06/09/2021 11:13:54 AM PDT by arkfreepdom
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To: Jyotishi

“Oppa Gangaram Style”


16 posted on 06/09/2021 11:22:19 AM PDT by yefragetuwrabrumuy ("Poor kids are just as bright, just as talented, as white kids." - Joe Biden Aug 8, 2019)
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To: nagant
It took only a few weeks to release Remdesivir monoclonal antibody vaccine.

I think you meant Regeneron.  Gilead's Remdesivir efficacy was less than 30% positive, if I recall correctly.

17 posted on 06/09/2021 11:38:10 AM PDT by Silent One ( )
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To: ransomnote; null and void; aragorn; AZ .44 MAG; Baynative; bgill; bitt; Black Agnes; blueyon; ...
.

PING

Monoclonal antibody can change Covid scenario: Gangaram Hospital

18 posted on 06/09/2021 12:35:26 PM PDT by LucyT
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To: ProtectOurFreedom

bookmark


19 posted on 06/09/2021 12:43:18 PM PDT by Irish Eyes
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To: arkfreepdom

The big news a couple days ago was that Regeneron sees the same improvement with a half-dose administered via injection rather than infusion.


20 posted on 06/09/2021 1:10:46 PM PDT by ProtectOurFreedom ("Pour les vaincre il faut de l'audace, encore de l'audace, toujours de l'audace")
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