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Stereotactic body radiotherapy (SBRT) is noninferior to conventional or moderately fractionated radiotherapy for localized prostate cancer (PC), according to a study. Nicholas van As and colleagues assessed whether SBRT is noninferior to conventionally or moderately hypofractionated regimens in patients with localized PC. The analysis included patients randomly assigned to SBRT (36.25 Gy in five fractions over one or two weeks) or control radiotherapy (78 Gy in 39 fractions over 7.5 weeks or 62 Gy in 20 fractions over four weeks). The researchers found that at a median follow-up of 74.0 months, the five-year incidence of freedom from biochemical or clinical...

Researchers have identified a protein that may prevent age-related macular degeneration (AMD), according to a new study published in the Developmental Cell on Oct. 2.AMD is the leading cause of vision loss among older adults, affecting nearly 20 million Americans. As the population ages, this number is expected to rise significantly. Currently, there are no treatments that can stop AMD’s progression.MR.PRAWET THADTHIAM/Shutterstock“I think we identified something that can target early-stage disease. ... That’s a big deal,” the study’s lead author Ruchira Singh, an associate professor of ophthalmology at the University of Rochester in New York, told The Epoch Times.The study...

A substantial number of patients with brain metastases who experience cognitive side effects following radiation therapy may fully regain cognitive function, according to a pooled analysis of three large, Phase III clinical trials. Recovery was more likely for people treated with conformal, or highly targeted, radiation techniques, compared to standard whole-brain treatment. The two most common types of conformal radiation are stereotactic radiosurgery (SRS), which delivers fewer, but higher doses of radiation per treatment to the tumor site, and hippocampal avoidance WBRT, which limits radiation exposure to the parts of the brain known to contribute to neurocognitive side effects that...

Researchers have identified a promising new combination therapy for metastatic colorectal cancer that enhances the effectiveness of existing treatment while reducing harmful side effects. The study focused on regorafenib, a drug that modestly improves survival in mCRC patients but often leads to severe toxicities. By pairing regorafenib with a dual JAK/HDAC inhibitor at low doses, the researchers were able to significantly boost the drug's anticancer activity. For patients with metastatic disease, treatment options are limited and the prognosis is often poor. Regorafenib, a multiple-kinase inhibitor, is one of the few drugs available for these patients; but its use is hampered...

A Minnesota man driving to couple’s therapy with his now-arrested ex-girlfriend told police that after a rocky morning spent arguing at home and then announcing he wanted to break up with her while they were in the car, things really took a turn for the worst when she allegedly forced him out of the vehicle and then “floored it” in order to run him over. Veronica Roleen Gast, 30, faces second-degree assault charges, according to a police affidavit obtained by Law&Crime on Wednesday. She is also charged with criminal vehicular operation – bodily harm, gross negligence, and domestic assault. The...

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system. These drugs eliminate the protein barriers that impede the immune system from recognizing and targeting cancer cells in the body. While there are multiple checkpoint inhibitors approved to treat different types of cancer, many patients don't respond or develop resistance to available regiments. A team has now found that ruxolitinib, an approved immunosuppressive drug, supercharged T-cell responses when used alongside checkpoint inhibitors—boosting their effectiveness in fighting cancer. These findings are supported by a Phase I clinical trial of patients with Hodgkin lymphoma, as well...

Patients with pancreatic cancer who received chemotherapy both before and after surgery experienced longer survival rates than would be expected from surgery followed by chemotherapy, according to a new study. The study included patients with pancreatic ductal adenocarcinoma (PDAC), which accounts for 90% of pancreatic cancers. An aggressive cancer with a high mortality rate, PDAC is predicted to become the second leading cause of cancer-related deaths in the U.S. by 2030. The findings are encouraging for the 15 to 20% of pancreatic cancer patients whose tumors are operable. The single-arm (only one treatment type or regimen) Phase II trial evaluated...

I am the boogeyman. Yes, according to the LGBTQ+ activists and their sympathizers, I am the terror that haunts their dreams. What am I? I’m a psychotherapist that offers help to individuals with undesired same-sex eroticization and want to explore change in their sexual attractions and behaviors. The activists label me a “conversion therapist,” expecting that to be sufficient to vilify me. My supervillain origin story is that God placed a burden on me in college when I saw my peers who struggle with unwanted same-sex attraction and behavior. These men were in a bind. If they shared with our...

For a third time, Sarepta Therapeutics has convinced a top Food and Drug Administration official to overrule the prevailing view of their staff and approve a drug for Duchenne muscular dystrophy. On Thursday evening, the FDA announced it expanded the approval of Elevidys, Sarepta’s Duchenne gene therapy, to cover nearly all patients, regardless of age or wheelchair status, despite the fact that the drug failed a large, Phase 3 trial last year. That decision, documents concurrently released by the agency show, was made almost exclusively by Peter Marks, the agency’s director of the Center for Biologics Evaluation and Research. He...

A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without compromising their safety, according to results of a clinical trial. The findings show the potential benefits of augmenting immunotherapy for this and other forms of cancer. Several years ago, researchers discovered that phosphatidylserine, a fatty substance called a phospholipid sometimes present on the surface of cancer cells, appeared to interact with immune cells to prevent them from attacking tumors. An antibody drug called bavituximab that neutralizes phosphatidylserine showed no effect on tumor response, progression, or survival when administered alone...

A man who was paralyzed from the neck down after a surfing accident seven years ago is now able to stand and walk on his own, thanks in part to a potentially groundbreaking stem cell treatment. Chris Barr was the very first patient in a Mayo Clinic study that collected stem cells from his own stomach fat, expanded them in a laboratory to 100 million cells and then injected the cells into Barr's lumbar spine. Over five years after undergoing the therapy, Barr said he is continuing to gain more independence and get faster at walking. "I never dreamed I...

Ibuprofen works wonders for your headaches, joint pain, muscle aches, and menstrual cramps, so it's probably no surprise that it's the second most common over-the-counter (OTC) drug behind paracetamol (Tylenol), according to a 2023 article https://pubmed.ncbi.nlm.nih.gov/36876700/ in the European Review for Medical and Pharmacological Sciences. You might get a prescription for ibuprofen if you have rheumatoid arthritis or osteoarthritis to reduce the pain and swelling from these conditions. Ibuprofen might also be used for psoriatic arthritis, arthritis of the spine, and gouty arthritis. Like other non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen works by blocking an enzyme that makes prostaglandins that cause...

TALLAHASSEE, Florida — Gov. Ron DeSantis sure seems to be acting like a candidate again — and he’s picking new fights with the most powerful Republican in America.During a lengthy call last week with more than 200 pledged delegates to his former presidential campaign, DeSantis shot down any speculation that he’d be Donald Trump’s vice president, warned the former president against using “identity politics” in choosing a running mate and blamed Trump’s campaign team for relentlessly attacking him before the governor dropped out of the presidential race in January.DeSantis held the call the same week he traveled to Indiana and...

Combining testosterone-blocking drugs in patients with prostate cancer relapse prevents the spread of cancer better than treatment with a single drug, a multi-institution, Phase 3 clinical trial led by researchers has found. The approach can extend the time between debilitating drug treatments without prolonging the time it takes to recover from each treatment. Prostate cancer is usually treated with one of several testosterone-lowering drugs for a set period of time. "This adds to a growing body of evidence in favor of more intensive testosterone-blocking therapy in patients with higher-risk prostate cancer," said Rahul Aggarwal, MD. The new study focused on...

The U.S. Supreme Court has declined to hear an appeal filed by a Christian therapist against Washington state's ban on "gay conversion therapy," allowing the law to remain in effect.In an orders list released Monday morning, the high court declined without comment a petition for a writ of certiorari in the case of Brian Tingley v. Robert W. Ferguson, Attorney General of Washington state, et al.The decision received separate dissenting opinions from Justices Clarence Thomas and Samuel Alito. Thomas claimed that Washington had "silenced one side of this debate" through state law."A law that restricts speech based on its content...

For ambulatory patients on systemic anticancer therapy, anticoagulants do not reduce the risk of arterial thrombotic events (ATEs) and are associated with increased bleeding risk, according to a review. Yan Xu, M.D. and colleagues examined the efficacy and safety of anticoagulants in ATE prevention among ambulatory cancer patients. The researchers performed a systematic review of studies comparing oral or parenteral anticoagulation with no anticoagulation among patients receiving systemic anticancer therapy with no other indication for anticoagulation. Data were included from 14 randomized trials involving low-molecular-weight heparins, direct oral anticoagulants, and warfarin. ATEs (myocardial infarction, ischemic stroke, intra-abdominal arterial embolism, or...

Boston University School of Law students were offered therapy after three controversial Supreme Court decisions this week about affirmative action, religious freedom and student debt forgiveness. The BU Law Student Government Association's (SGA) statement, sent out to law students Friday afternoon, denounced the three Supreme Court decisions of the week: Students for Fair Admissions v. Harvard, 303 Creative LLC. v. Elenis and Biden v. Nebraska. In an email obtained by Fox News Digital, the student board began by lambasting the Supreme Court's decision in the Students for Fair Admissions case, which declared race-based affirmative action in college admissions is unconstitutional....

Low-level laser therapy and associated photobiomodulation is the most effective of the known treatments for tinnitus, according to a study comparing the main therapies in current use. Often described as ringing or hissing in the ears, it is considered a symptom rather than a disease, but is unpleasant and in some cases incapacitating. Its known causes can range from a buildup of earwax and insufficient peripheral irrigation in the inner ear to brain damage and bruxism. Panhóca and his team tested alternative and complementary treatments for idiopathic (with no apparent cause) and refractory tinnitus on more than 100 men and...

Bill Barr has been on every leftwing media Sunday show spewing his poison. He has smeared Trump more than he has ever criticized the worse drug dealers, arms dealers, international terrorists, terrorist states, or the Biden crime family and the millions of dollars they received from our enemies, including communist China. Barr knows he’s lying. He knows the thug prosecutors against Trump have acted appallingly. He knows all this. But on Father’s Day he spends part of his morning on CBS trashing Trump without any serious challenge. I think Barr is sick and getting sicker.

Former Attorney General Bill Barr said Sunday on CBS’s “Face the Nation” that former President Donald Trump’s federal charges can not be turned into a “a therapy session for a troubled man.” Co-host Robert Costa said, “So many Republicans continue to defend him. What will it say if the party, your long-time party, puts them forward as their nominee?”