Posted on 01/21/2026 6:52:41 AM PST by daniel1212
Many people who successfully lost weight on Ozempic and other GLP-1 agonist drugs are having trouble weaning themselves off the injectables, according to the BBC, because the hunger for food comes roaring back with a vengeance — and hence the pounds start creeping up again, hinting that patients are likely to develop life-long dependencies on the substances.
“For the first 38 years of my life, I was overweight — now I’m six stone (38kg) [83 pounds] lighter,” Tanya Hall, a Wegovy user who can’t get off the drug, told the news organization. “Therefore, there’s part of me that feels like there’s an addiction to keep it going because it makes me feel the way that I feel, it makes me feel in control.”
This is borne out by research that found patients who stop using these medications often gain much of their weight back....
For patients who do get off the drugs, they tend to gain two thirds of their lost weight back, according to research by Ozempic maker Novo Nordisk. Physician Hussain Al-Zubaidi told the BBC that he’s seen patients gain 60 to 80 percent back of the weight they lost.
(Excerpt) Read more at futurism.com ...
1/3 loss is great but sadly it seems it’s the muscle that is largely lost which is nt at all great.
If gaining a lot of stone back, use smaller stones.
The discipline to restrict calories is where it’s at.
A spoonful of peanut butter takes a couple hours of moderate exercise to burn off. It’s like a rounding error in terms of portion size.
You are so right, anyone with half a brain could see this coming from a mile away, the drug companies don’t make drugs for a one-time use, they make drugs that you get hooked on and can’t get off of.
Except of course there’s a lot more that goes into weight than self-discipline. Genetics is big.
How izat GLP-1 nitemare feeling this morning? How much pain can you endure today from the medication before you collapse in bed completely exhausted. And you cant eat because YOU WILL VOMIT your guts out because your stomach shrunk down to 1/4 its normal size. If you cant eat, you will lose weight.
I screamed at my doctor every cramp I got from that crap. GLP-1 meds are not allowed in the house. And I have a new doctor.
I don’t know anyone on these drugs - but I can’t imagine the long-term effects, especially (I imagine) to liver and kidneys.
My doc says the FDA set the dosage MUCH higher than it should be for GLP...others prob too...gee...wonder why...he says the dosage should be much lower.
Its 90% muscle that goes. Your body shape will change. I cant get anything back. I’m 60.
As we age, we tend to experience age-related, progressive loss of muscle mass ,(Sarcopenia).
If you take weight loss drugs, I recommend you start walking, and lifting a few weights. Doesn't have to be anything crazy.
having trouble weaning themselves off the injectables, according to the BBC, because the hunger for food comes roaring back with a vengeance — exactly as designed for maximum profitability.
Excellent advice and true.
Eh, I come from healthy peasant stock. I will eat whatever is on a plate in front of me until it is gone, both because of that was how I was raised (3/4 grandparents in the Shoah) and because I have a strong appetite, which is probably genetic due to it being a survival trait that helped my ancestors survive hard times.
To add to this, I am extremely tall (hence “Jewbacca”) and a mesomorph (just big, physically).
I wouldn’t be “fat” medically if I ate what I wanted (I work out a lot), but I would not be lean.
Unfortunately, I am a career pilot and have to be under a certain weight to make physical for the ejection seat. At 15% body fat, I won’t make weight. And I would get grounded.
So, through sheer force of will (and an helpful/understanding wife) I’ve maintained weight. It’s been extremely difficult. Basically I eat fish and vegetables and have since I was a kid.
It’s unpleasant and expensive, so I get why most won’t do it.
On the bright side, my wife thinks I look amazing naked, which explains the 9 daughters!
“For patients who do get off the drugs, they tend to gain two thirds of their lost weight back”
That’s no different than most diets without the drugs. People lose the weight and then gain a lot of it back again. I’ve been through that cycle three times in my 74 years.
I’m on cycle #4 now and have lost 28 pounds since last July (no drugs). This time I’m determined to not let it come back.
Hear me out on this because I have very close secondhand experience with it. Hypnotism... My dad could NOT stop smoking. He tried everything, but the stress of his job was too much and he always started up again. A buddy of his from the mill stopped and dad asked him what he did. The guy told him he went to see a hypnotist and hadn’t smoked since. Dad went to the same guy and quit for almost fifteen years until he started again after a really bad motorcycle accident damn near killed him. Could work for some of these folks.
Bless you and yours
This is also true for many people who have gastric surgery.
Not sure it is about the drug.
Interesting observations and story, Jim.
“I thought about food like an addict thinks about meth or crack”
I understand that completely. You stop eating to live and just live to eat. It’s a hard cycle to stop. I’m down 28 pounds since last July and still think about what to eat.
You win the internets for the day.
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