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Posted on 07/16/2025 11:35:34 AM PDT by Red Badger
A mouse study has found the sugar 2-deoxy-D-ribose stimulates hair regrowth.
Put down the rosemary oil and pause the red light therapy, research suggests the secret to curing male pattern baldness could lie in a sugar that occurs naturally in our bodies.
In a mouse model of testosterone-driven hair loss, the sugar, called 2-deoxy-D-ribose, stimulated hair regrowth just as effectively as existing treatment minoxidil – the active ingredient in Rogaine.
Though commonly referred to as male pattern baldness, the condition, also known as hereditary-patterned baldness or androgenetic alopecia, affects women too. In fact, up to 40 percent of people experience it, making it the most common cause of hair loss worldwide. Symptoms typically begin in a person's 20s and 30s, or after menopause. We still don’t know for sure what causes it, but it’s thought that a combination of genetics, hormones, and aging all play a part.
Treatment options are currently limited, so breakthroughs like this one, even if they’re limited to mice for now, are very promising.
“Male pattern baldness is such a common condition, affecting men all over the world, but at the moment there are only two FDA licensed drugs to treat it,” Professor Sheila MacNeil, Emeritus Professor of Tissue Engineering at the University of Sheffield, said in a statement.
“Our research suggests that the answer to treating hair loss might be as simple as using a naturally occurring deoxy ribose sugar to boost the blood supply to the hair follicles to encourage hair growth.”
You might remember the name deoxyribose from science class – it’s the sugar that, along with phosphate, makes up the backbone of DNA. As a result, it plays an important role in DNA stability, replication, and repair.
The team were initially investigating its capacity to speed up wound healing by promoting blood vessel formation, before noticing that mice treated with the sugar had much faster hair regrowth.
Pivoting to study its potential as a hair loss treatment, the researchers smeared a small dose of the sugar, in gel form, onto balding male mice. They also tested some mice using minoxidil, and some with both deoxyribose and minoxidil.
Within weeks, minoxidil and the sugar gel promoted a similar level of hair regrowth (80 to 90 percent), however no significant benefit was observed by applying the two in combination.
The scientists still don’t understand quite how the deoxyribose gel stimulates longer and thicker hair growth in mice, though they suggest it could have something to do with increased blood supply to the hair follicles. Because of this, it may also work on other causes of hair loss, such as chemotherapy-induced alopecia.
It remains to be seen if the same effects can be replicated in humans, but if they can, this could prove an inexpensive alternative to the current treatment options for male pattern baldness.
"This is a badly under-researched area, and hence new approaches are needed," write the authors.
“The research we have done is very much early stage, but the results are promising and warrant further investigation,” concluded MacNeil. “This could offer another approach to treating this condition which can affect men’s self-image and confidence.”
The study is published in Frontiers in Pharmacology.
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God created a few perfect heads, the rest he had to cover with hair.
Grow mouse hair on men?
2-Deoxy-D-Ribose Sugar Gel, Deoxyribose Sugar Gel Hair Growth: A hair growth product that claims to prevent hair loss and promote growth, while also inhibiting oiliness. It is applied directly on the scalp using a micro-spray and left overnight for best results.
Ribogrow Hair Booster Tonic - 3 x 50ml: A hair loss treatment that contains 2-deoxy-D-ribose as an active ingredient. It is designed to stimulate the hair root in cases of hereditary hair loss and promote hair growth at the root. The tonic is applied morning and evening onto the areas affected by hair loss and massaged in gently.
Pure D-Ribose Powder, 1 KG (2.2 Pound & 200 Servings): A dietary supplement that contains D-ribose, a simple sugar molecule naturally produced within the body. It is used for cellular energy support and is popular among athletes for energy enhancement and muscle recovery.
2-Deoxy-D-Ribose (Chem-Impex): A product used in research focused on energy production, genetic research, medical applications, supplement industry, and pharmaceutical development. It is a vital sugar in energy metabolism, essential for ATP production.
2-Deoxy-D-Ribose Alginate Gel: A gel prepared from sodium alginate, propylene glycol, 2-phenoxyethanol, and 2dDR. It is used for the delivery of bioactive agents that promote wound healing and has antimicrobial activity against various bacteria.
You can buy it on E-bay for 10 bucks.
Why does male pattern baldness need a cure?
Just because.
“Grow mouse hair on men?”
I have one friend who would gladly take it.
I must have the opposite condition. I’ve been on chemo and radiation so much I’ve lost all my body hair over the last ten years or so. Except for scalp and beard.
I found shaving my head cured my male pattern baldness.
Truer words were never written or stated.
Can you use the oral supplement or does it have to be applied to the scalp?
Not really, but I do remember Karen Schemansky.......She had the biggest...
Because guys are unhappy with having their head sunburned?
deoxyribose nucleic acid..................
Fuzzy gray stuff .... LOL
That is unusual, CG. Of course, losing body hair is normal after 70. Are you past the seven-0? Ask your Doctors about a Niacinimide supplement. My wife and I started using it and it has thickened our hair, apparently.
I turned 79 last week. I still have a full head of hair, but that’s about it.
Post #4 has some information.
Who cares, I learned more from Karen Schemansky than I ever learned about DNA.......
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