Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Fentanyl Vaccine [?] Potential ‘Game Changer’ for Opioid Epidemic
neurosciencenews.com ^ | November 14, 2022 | University of Houston

Posted on 11/14/2022 4:12:28 PM PST by BenLurkin

A research team led by the University of Houston has developed a vaccine targeting the dangerous synthetic opioid fentanyl that could block its ability to enter the brain, thus eliminating the drug’s “high.”

The breakthrough discovery could have major implications for the nation’s opioid epidemic by becoming a relapse prevention agent for people trying to quit using opioids. While research reveals Opioid Use Disorder (OUD) is treatable, an estimated 80% of those dependent on the drug suffer a relapse.

The findings, published in the journal Pharmaceutics, could not be timelier or more in demand: Over 150 people die every day from overdoses of synthetic opioids including fentanyl, which is 50 times stronger than heroin and 100 times stronger than morphine. Consumption of about 2 milligrams of fentanyl (the size of two grains of rice) is likely to be fatal depending on a person’s size.

In another positive finding, the vaccine did not cause any adverse side effects in the immunized rats involved in lab studies. The team plans to start manufacturing clinical-grade vaccine in the coming months with clinical trials in humans planned soon.

“The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,” said Haile.

(Excerpt) Read more at neurosciencenews.com ...


TOPICS: Science
KEYWORDS: fentanyl; fentanylvaccine; vaccine
Navigation: use the links below to view more comments.
first previous 1-2021-37 last
To: George from New England

I foresee a great increase in overdoses if they try this on addicts. The normal response of an addict is to increase the dose as the body becomes tolerate to the drug.


21 posted on 11/14/2022 4:50:59 PM PST by Kadric
[ Post Reply | Private Reply | To 3 | View Replies]

To: Kadric

That’s a feature not a flaw.


22 posted on 11/14/2022 4:53:07 PM PST by BipolarBob (I was born into this world with nothing . . and I still have most of it .)
[ Post Reply | Private Reply | To 21 | View Replies]

To: Hammerhead

Why bother. It is cleaning the gene pool. Give all the druggies an overdose. Problem solved in many areas.


23 posted on 11/14/2022 4:57:50 PM PST by oldasrocks
[ Post Reply | Private Reply | To 12 | View Replies]

To: dynachrome

“How about if you get a shot of narcan for an overdose, the EMT gives you the fentanyl ‘vaccine’ right afterward?”

how about NO.

I this is a super slippery slope. But I think if you ask the person when they recover if they want to be protected from fenty, but the fix will not preclude heroin highs the odds are that they will agree.

Always ask before using force as it gives better optics.

P.S. we are having a gun buyback please come and give us your guns. p.s. bring your assault weapon ammo too and we will donate it to the needy Ukrainians.


24 posted on 11/14/2022 4:59:24 PM PST by algore
[ Post Reply | Private Reply | To 6 | View Replies]

To: monkeyshine

I had a colonoscopy earlier this year and they used fentanyl as a light sedative before the anesthetic. I was really surprised at that, but let them go ahead. Things turned out fine.


25 posted on 11/14/2022 5:09:34 PM PST by ProtectOurFreedom (If you're not part of the solution, you're just scumming up the bottom of the beaker!)
[ Post Reply | Private Reply | To 19 | View Replies]

To: George from New England

Maybe they are doing cocaine or heroin and don’t want to die from an accidental overdose of fentanyl that has been mixed in.


26 posted on 11/14/2022 5:11:33 PM PST by Blood of Tyrants (Inside every leftist is a blood-thirsty fascist yearning to be free of current societal constraints.)
[ Post Reply | Private Reply | To 3 | View Replies]

To: BenLurkin

If the vaccine is only specific or it’s derivative, but not other opiates, the addict is just gonna use the opiates that get to the brain.....the addicts always find something else.
The drug distributors will make a more potent opiate derivative. False hope is a strong addiction also.


27 posted on 11/14/2022 5:22:12 PM PST by Getready (Wisdom is more valuable than gold and harder to find.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BenLurkin

“The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,” said Haile.

So the addict will switch to meth, coke, or heroin.


28 posted on 11/14/2022 5:25:13 PM PST by Flick Lives (Cui bono)
[ Post Reply | Private Reply | To 1 | View Replies]

To: dvan
SAFE

EFFECTIVE

PREVENTS OVERDOSE

HALTS ADDICTION

IN RARE CAUSES A SECOND NOSE TO GROW OUT OF YOUR FOREHEAD (But this is usually rare.)

.

/sarc

29 posted on 11/14/2022 5:28:24 PM PST by GaltAdonis
[ Post Reply | Private Reply | To 4 | View Replies]

To: hinckley buzzard

Exactly. And fat and carb absorption blockers...still got overweight diabetics. Chantix for tobacco smoking didn’t work too well either.


30 posted on 11/14/2022 5:29:14 PM PST by Getready (Wisdom is more valuable than gold and harder to find.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: BenLurkin

I have another idea. Don’t take fentanyl.


31 posted on 11/14/2022 5:59:51 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BenLurkin

“The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,” said Haile.
-

So they take heroin or OxyContin instead. Etc…


32 posted on 11/14/2022 6:01:20 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
[ Post Reply | Private Reply | To 1 | View Replies]

To: George from New England

Is it just me... or would a valid hypothesis of this will lead to more overdoses as people will simply try and take more?


33 posted on 11/14/2022 6:15:24 PM PST by rwilson99 (How exactly would John 3:16 not apply to Mary?)
[ Post Reply | Private Reply | To 3 | View Replies]

To: rwilson99

You are absolutely correct. Already, addicts are given pills to block them from feeling high.
Sometimes they will use drugs while on those pills. Because they don’t feel the high, they can accidentally overdose.


34 posted on 11/14/2022 7:17:30 PM PST by Tired of Taxes
[ Post Reply | Private Reply | To 33 | View Replies]

To: BenLurkin

Big pharma and their sycophants have forever made me extremely wary of any and all vaccines


35 posted on 11/14/2022 7:22:04 PM PST by BlueMondaySkipper (Involuntarily subsidizing the parasite class since 1981)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Hammerhead

You forget the real reason for these remedies. This is not about helping the junkies. It’s about getting more money out of the system under the guise of helping the junkies. Just like rehab clinics, it’s the cash flow they are looking for.


36 posted on 11/15/2022 4:33:06 AM PST by dgbrown
[ Post Reply | Private Reply | To 12 | View Replies]

To: BenLurkin

Well one fentanyl didn’t work, let’s try another and another and another.


37 posted on 11/16/2022 6:10:25 PM PST by Zack Attack
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-37 last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson